Most-cited papers on Clinical Translation

Ranked by citation count via OpenAlex. Citations update on a rolling basis; list regenerates every 24h.

1. Motor Control: Translating Research into Clinical Practice

   2006 · Touro Scholar (Touro College) · Shumway‐Cook, Anne, Woollacott, Marjorie

   1,991 cited

2. Targeted polymeric therapeutic nanoparticles: design, development and clinical translation

   2012 · Chemical Society Reviews · Kamaly, Nazila, Xiao, Zeyu, Valencia, Pedro M. et al.

   1,694 cited

3. The Onpattro story and the clinical translation of nanomedicines containing nucleic acid-based drugs

   2019 · Nature Nanotechnology · Akinc, Akin, Maier, Martin A., Manoharan, Muthiah et al.

   1,537 cited

4. Clinical translation of angiogenesis inhibitors

   2002 · Nature reviews. Cancer · Kerbel, Robert S., Folkman, Judah

   1,511 cited

5. mRNA vaccines for infectious diseases: principles, delivery and clinical translation

   2021 · Nature Reviews Drug Discovery · Chaudhary, Namit, Weissman, Drew, Whitehead, Kathryn A.

   1,449 cited

6. Translating guidelines into practice. A systematic review of theoretic concepts, practical experience and research evidence in the adoption of clinical practice guidelines.

   1997 · PubMed · Davis, Dave A., Taylor‐Vaisey, Anne

   1,227 cited

7. Glutamine: Metabolism and Immune Function, Supplementation and Clinical Translation

   2018 · Nutrients · Cruzat, Vínicius Fernandes, Rogero, Marcelo Macedo, Keane, Kevin N. et al.

   1,131 cited

8. Preclinical Development and Clinical Translation of a PSMA-Targeted Docetaxel Nanoparticle with a Differentiated Pharmacological Profile

   2012 · Science Translational Medicine · Hrkach, Jeffrey S., Hoff, Daniel D. Von, Ali, Mir Mukkaram et al.

   1,115 cited

9. IL-10 Family Cytokines IL-10 and IL-22: from Basic Science to Clinical Translation

   2019 · Immunity · Ouyang, Wenjun, O’Garra, Anne

   1,043 cited

10. Lost in translation: animal models and clinical trials in cancer treatment.

    2014 · PubMed · Mak, Isabella W.Y., Evaniew, Nathan, Ghert, Michelle

    970 cited

11. Current Trends and Challenges in the Clinical Translation of Nanoparticulate Nanomedicines: Pathways for Translational Development and Commercialization

    2018 · Frontiers in Pharmacology · Hua, Susan, Matos, María, Metselaar, Josbert M. et al.

    931 cited

12. Clinical Research to Clinical Practice — Lost in Translation?

    2003 · New England Journal of Medicine · Lenfant, Claude

    916 cited

13. Translation of microarray data into clinically relevant cancer diagnostic tests using gene expression ratios in lung cancer and mesothelioma.

    2002 · PubMed · Gordon, Gavin J., Jensen, Roderick V., Hsiao, Li-Li et al.

    881 cited

14. Behavioral models of impulsivity in relation to ADHD: Translation between clinical and preclinical studies

    2006 · Clinical Psychology Review · Winstanley, Catharine A., Eagle, Dawn M., Robbins, Trevor W.

    845 cited

15. DNA damage repair: historical perspectives, mechanistic pathways and clinical translation for targeted cancer therapy

    2021 · Signal Transduction and Targeted Therapy · Huang, Ruixue, Zhou, Ping‐Kun

    840 cited

16. Translating RNA sequencing into clinical diagnostics: opportunities and challenges

    2016 · Nature Reviews Genetics · Byron, Sara A., Keuren‐Jensen, Kendall Van, Engelthaler, David M. et al.

    836 cited

17. Translating Clinical Research into Clinical Practice: Impact of Using Prediction Rules To Make Decisions

    2006 · Annals of Internal Medicine · Reilly, Brendan M., Evans, Arthur T.

    803 cited

18. Design of biodegradable, implantable devices towards clinical translation

    2019 · Nature Reviews Materials · Li, Chunmei, Guo, Chengchen, Fitzpatrick, Vincent et al.

    769 cited

19. Stimuli-responsive polymers: Biomedical applications and challenges for clinical translation

    2012 · Advanced Drug Delivery Reviews · Hoffman, Allan S.

    745 cited

20. Clinical Translation of Nanomedicine

    2015 · Chemical Reviews · Min, Yuanzeng, Caster, Joseph M., Eblan, Michael J. et al.

    743 cited

21. Literature Review of Methods to Translate Health-Related Quality of Life Questionnaires for Use in Multinational Clinical Trials

    2008 · Value in Health · Acquadro, C., Conway, Katrin, Hareendran, Asha et al.

    703 cited

22. Lost in translation: the valley of death across preclinical and clinical divide – identification of problems and overcoming obstacles

    2019 · Translational Medicine Communications · Seyhan, Attila A.

    695 cited

23. Clinical translation of an ultrasmall inorganic optical-PET imaging nanoparticle probe

    2014 · Science Translational Medicine · Phillips, Evan H., Medina, Oula Peñate, Zanzonico, Pat et al.

    691 cited

24. Genetics of coronary artery disease: discovery, biology and clinical translation

    2017 · Nature Reviews Genetics · Khera, Amit V., Kathiresan, Sekar

    684 cited

25. Microfluidic technologies for accelerating the clinical translation of nanoparticles

    2012 · Nature Nanotechnology · Valencia, Pedro M., Farokhzad, Omid C., Karnik, Rohit et al.

    677 cited

26. Analysis of Cancer Metabolism by Imaging Hyperpolarized Nuclei: Prospects for Translation to Clinical Research

    2011 · Neoplasia · Kurhanewicz, John, Vigneron, Daniel B., Brindle, Kevin M. et al.

    674 cited

27. Nanogels: An overview of properties, biomedical applications and obstacles to clinical translation

    2015 · Journal of Controlled Release · Soni, Kruti S., Desale, Swapnil S., Bronich, Tatiana K.

    648 cited

28. The gut microbiome and liver cancer: mechanisms and clinical translation

    2017 · Nature Reviews Gastroenterology & Hepatology · Yu, Le‐Xing, Schwabe, Robert F.

    633 cited

29. Inflammation in intracerebral hemorrhage: From mechanisms to clinical translation

    2013 · Progress in Neurobiology · Zhou, Yu, Wang, Yanchun, Wang, Jian et al.

    621 cited

30. Stem cells in human neurodegenerative disorders — time for clinical translation?

    2010 · Journal of Clinical Investigation · Lindvall, Olle, Kokaia, Zaal

    610 cited