Most-cited papers on Concentration dependent effects

Ranked by citation count via OpenAlex. Citations update on a rolling basis; list regenerates every 24h.

1. Dose-dependent effects of folic acid on blood concentrations of homocysteine: a meta-analysis of the randomized trials

   2005 · American Journal of Clinical Nutrition · Clarke, R

   453 cited

2. Ginseng Therapy in Non-Insulin-Dependent Diabetic Patients: Effects on psychophysical performance, glucose homeostasis, serum lipids, serum aminoterminalpropeptide concentration, and body weight

   1995 · Diabetes Care · Sotaniemi, Eero A., Haapakoski, Eila, Rautio, Arja

   376 cited

3. Concentration-dependent Effects of Nitric Oxide on Mitochondrial Permeability Transition and Cytochrome cRelease

   2000 · Journal of Biological Chemistry · Brookes, Paul S., Salinas, Emmanuel Padilla, Darley-Usmar, Kenta et al.

   323 cited

4. Characterization of orientation-dependent etching properties of single-crystal silicon: effects of KOH concentration

   1998 · Sensors and Actuators A Physical · Sato, Kazuo, Shikida, Mitsuhiro, Matsushima, Yoshihiro et al.

   321 cited

5. Effects of Buprenorphine Maintenance Dose on μ-Opioid Receptor Availability, Plasma Concentrations, and Antagonist Blockade in Heroin-Dependent Volunteers

   2003 · Neuropsychopharmacology · Greenwald, Mark K., Johanson, Chris‐Ellyn, Moody, David E. et al.

   313 cited

6. Concentration‐ and composition‐dependent effects of metal ions on human MG‐63 osteoblasts

   2002 · Journal of Biomedical Materials Research · Hallab, Nadim J., Vermes, Csaba, Messina, Carlo et al.

   275 cited

7. Concentration-dependent effects of cytochalasin D on tight junctions and actin filaments in MDCK epithelial cells

   1994 · Journal of Cell Science · Stevenson, Bruce R., Begg, David A.

   242 cited

8. Glucocorticoids exert opposing effects on macrophage function dependent on their concentration

   2007 · Immunology · Lim, Hee‐Young, Müller, Nora, Herold, Marco J. et al.

   212 cited

9. Concentration-dependent effects of tolbutamide, meglitinide, glipizide, glibenclamide and diazoxide on ATP-regulated K+ currents in pancreatic B-cells

   1988 · Naunyn-Schmiedeberg s Archives of Pharmacology · Z�nkler, B. J., Lenzen, Sigurd, Männer, K. et al.

   210 cited

10. Effects of concentration-dependent plasma protein binding on ceftriaxone kinetics

    1981 · Clinical Pharmacology & Therapeutics · Stoeckel, K., McNamara, Patrick J., Brandt, Roger D. et al.

    204 cited

11. Concentration-dependent effects of sodium butyrate in Chinese hamster cells: cell-cycle progression, inner-histone acetylation, histone H1 dephosphorylation, and induction of an H1-like protein

    1980 · Biochemistry · D'Anna, Joseph A., Tobey, Robert A., Gurley, L.R.

    199 cited

12. Randomized, Double-Blind, Placebo-Controlled Study on Effects of Raloxifene and Hormone Replacement Therapy on Plasma NO Concentrations, Endothelin-1 Levels, and Endothelium-Dependent Vasodilation in Postmenopausal Women

    2001 · Arteriosclerosis Thrombosis and Vascular Biology · Saitta, Antonino, Altavilla, Domenica, Cucinotta, Domenico et al.

    188 cited

13. Concentration-dependent effects of dentin phosphophoryn in the regulation of in vitro hydroxyapatite formation and growth

    1990 · Bone and Mineral · Boskey, Adele L., Maresca, Michael, Doty, Steven et al.

    187 cited

14. Antibacterial effects of iron oxide (Fe3O4) nanoparticles: distinguishing concentration-dependent effects with different bacterial cells growth and membrane-associated mechanisms

    2019 · Applied Microbiology and Biotechnology · Gabrielyan, Lilit, Hovhannisyan, Ashkhen, Gevorgyan, Vladimir et al.

    168 cited

15. Effects of Concentration-Dependent Elastic Modulus on Diffusion-Induced Stresses for Battery Applications

    2010 · Journal of The Electrochemical Society · Deshpande, Rutooj D., Qi, Yue, Cheng, Yang‐Tse

    167 cited

16. Dissection of antigenic and irritative effects of epicutaneously applied haptens in mice. Evidence that not the antigenic component but nonspecific proinflammatory effects of haptens determine the concentration-dependent elicitation of allergic contact dermatitis.

    1996 · Journal of Clinical Investigation · Grabbe, Stephan, Steinert, Meike, Mahnke, Karsten et al.

    155 cited

17. Effects of dietary daidzein and its metabolite, equol, at physiological concentrations on the growth of estrogen-dependent human breast cancer (MCF-7) tumors implanted in ovariectomized athymic mice

    2006 · Carcinogenesis · Ju, Young H., Fultz, Jodi, Allred, Kimberly F. et al.

    154 cited

18. Concentration- and Time-dependent Effects of the Synthetic Estrogen, 17α-ethinylestradiol, on Reproductive Capabilities of the Zebrafish,<i>Danio rerio</i>

    2007 · Journal of Toxicology and Environmental Health · Schäfers, Christoph, Teigeler, Matthias, Wenzel, Andrea et al.

    150 cited

19. Concentration-dependent cytotoxicity of copper ions on mouse fibroblasts in vitro: effects of copper ion release from TCu380A vs TCu220C intra-uterine devices

    2012 · Biomedical Microdevices · Cao, Bianmei, Zheng, Yudong, Xi, Tingfei et al.

    147 cited

20. Effects of 1 and 3 g cinnamon on gastric emptying, satiety, and postprandial blood glucose, insulin, glucose-dependent insulinotropic polypeptide, glucagon-like peptide 1, and ghrelin concentrations in healthy subjects

    2009 · American Journal of Clinical Nutrition · Hlebowicz, Joanna, Hlebowicz, Anna, Lindstedt, Sandra et al.

    147 cited

21. Effects of Cr concentrations on the microstructure, hardness, and temperature-dependent tribological properties of Cr-DLC coatings

    2013 · Applied Surface Science · Zou, C.W., Wang, H.J., Feng, L. et al.

    145 cited

22. Sex Reversal Effects of Environmentally Relevant Xenobiotic Concentrations on the Red-Eared Slider Turtle, a Species with Temperature-Dependent Sex Determination

    1999 · General and Comparative Endocrinology · Willingham, Emily, Crews, David

    141 cited

23. Structure-Dependent Charge Transport and Storage in Self-Assembled Monolayers of Compounds of Interest in Molecular Electronics:  Effects of Tip Material, Headgroup, and Surface Concentration

    2004 · Journal of the American Chemical Society · Fan, Fu-Ren F., Yao, Yuxing, Cai, Lintao et al.

    138 cited

24. Soluble Neuregulin-1 Has Bifunctional, Concentration-Dependent Effects on Schwann Cell Myelination

    2010 · Journal of Neuroscience · Syed, Neeraja, Reddy, Kavya, Yang, David P. et al.

    136 cited

25. Chloroquine serum concentration and side effects: Evidence for dose‐dependent kinetics

    1979 · Clinical Pharmacology & Therapeutics · Frisk‐Holmberg, Marianne, Bergkvist, Yngve, Domeij-Nyberg, B. et al.

    134 cited

26. Distinct Concentration-Dependent Effects of the Polo-like Kinase 1–Specific Inhibitor GSK461364A, Including Differential Effect on Apoptosis

    2009 · Cancer Research · Gilmartin, Aidan G., Bleam, Maureen R., Richter, Mark C. et al.

    133 cited

27. Time- and Concentration-Dependent Effects of Dissolution Products of 58S Sol–Gel Bioactive Glass on Proliferation and Differentiation of Murine and Human Osteoblasts

    2004 · Tissue Engineering · Bielby, Robert C., Christodoulou, Ioannis, Pryce, Russell S. et al.

    130 cited

28. Dose-dependent effects of rosmarinic acid on formation of oxidatively stressed myofibrillar protein emulsion gel at different NaCl concentrations

    2017 · Food Chemistry · Wang, Shuangxi, Zhang, Yumeng, Chen, Lin et al.

    125 cited

29. Modeling Multibody Effects in Ionic Solutions with a Concentration Dependent Dielectric Permittivity

    2006 · Physical Review Letters · Hess, Berk, Holm, Christian, Vegt, Nico F. A. van der

    123 cited

30. Concentration-dependent effects of CSF1R inhibitors on oligodendrocyte progenitor cells ex vivo and in vivo

    2019 · Experimental Neurology · Liu, Yiting, Given, Katherine S., Dickson, Erin L. et al.

    117 cited