Most-cited papers on Diagnostic and Prognostic Markers

Ranked by citation count via OpenAlex. Citations update on a rolling basis; list regenerates every 24h.

1. Limitations of the Odds Ratio in Gauging the Performance of a Diagnostic, Prognostic, or Screening Marker

   2004 · American Journal of Epidemiology · Pepe, M. S.

   1,251 cited

2. Matrix metalloproteinases in cancer: their value as diagnostic and prognostic markers and therapeutic targets

   2013 · Tumor Biology · Hadler‐Olsen, Elin, Winberg, Jan‐Olof, Uhlin‐Hansen, Lars

   358 cited

3. Ki-67 and other proliferation markers useful for immunohistological diagnostic and prognostic evaluations in human malignancies.

   1990 · PubMed · Gerdes, Johannes

   307 cited

4. Circulating miR‐221 directly amplified from plasma is a potential diagnostic and prognostic marker of colorectal cancer and is correlated with p53 expression

   2010 · Journal of Gastroenterology and Hepatology · Pu, Xingxiang, Huang, Guoliang, Guo, Hongqiang et al.

   290 cited

5. Molecular pathology in adult gliomas: diagnostic, prognostic, and predictive markers

   2010 · The Lancet Neurology · Jansen, Michael, Yip, Stephen, Louis, David N.

   275 cited

6. Biomarkers in respiratory tract infections: diagnostic guides to antibiotic prescription, prognostic markers and mediators

   2007 · European Respiratory Journal · Christ‐Crain, Mirjam, Müller, Christian

   247 cited

7. Diagnostic and prognostic value of hematological and immunological markers in COVID-19 infection: A meta-analysis of 6320 patients

   2020 · PLoS ONE · Elshazli, Rami M., Toraih, Eman A., Elgaml, Abdelaziz et al.

   231 cited

8. Comparison of 10 serum bone turnover markers in prostate carcinoma patients with bone metastatic spread: Diagnostic and prognostic implications

   2004 · International Journal of Cancer · Jung, Klaus, Lein, Michael, Stephan, Carsten et al.

   226 cited

9. Diagnostic and Prognostic Utility of the Synaptic Marker Neurogranin in Alzheimer Disease

   2016 · JAMA Neurology · Tarawneh, Rawan, D’Angelo, Gina, Crimmins, Dan L. et al.

   222 cited

10. Assessing the incremental value of diagnostic and prognostic markers: a review and illustration

    2011 · European Journal of Clinical Investigation · Steyerberg, Ewout W., Pencina, Michael, Lingsma, Hester F. et al.

    210 cited

11. Adjusting for Covariates in Studies of Diagnostic, Screening, or Prognostic Markers: An Old Concept in a New Setting

    2008 · American Journal of Epidemiology · Janes, Holly, Pepe, M. S.

    203 cited

12. Role of PD-L1 Expression in Non-Small Cell Lung Cancer and Their Prognostic Significance according to Clinicopathological Factors and Diagnostic Markers

    2019 · International Journal of Molecular Sciences · Pawełczyk, Konrad, Piotrowska, Aleksandra, Ciesielska, Urszula et al.

    200 cited

13. Noninvasive Urinary Metabolomic Profiling Identifies Diagnostic and Prognostic Markers in Lung Cancer

    2014 · Cancer Research · Mathé, Ewy A., Patterson, Andrew D., Haznadar, Majda et al.

    196 cited

14. Cardiac troponin I as diagnostic and prognostic marker in severe heart failure

    2000 · The Journal of Heart and Lung Transplantation · Vecchia, Luigi La, Mezzena, Gabriella, Zanolla, Luisa et al.

    193 cited

15. Matrix metalloproteinases as diagnostic (MMP-13) and prognostic (MMP-2, MMP-9) markers of prostate cancer

    2004 · Urological Research · Morgia, Giuseppe, Falsaperla, Mario, Malaponte, Grazia et al.

    191 cited

16. Procalcitonin as a diagnostic marker and IL-6 as a prognostic marker for sepsis

    2013 · Diagnostic Microbiology and Infectious Disease · Jekarl, Dong Wook, Lee, Soyoung, Lee, Jehoon et al.

    182 cited

17. Machine learning classification with confidence: Application of transductive conformal predictors to MRI-based diagnostic and prognostic markers in depression

    2010 · NeuroImage · Nouretdinov, Ilia, Costafreda, Sergi G., Gammerman, Alex et al.

    171 cited

18. c-Met and PD-L1 on Circulating Exosomes as Diagnostic and Prognostic Markers for Pancreatic Cancer

    2019 · International Journal of Molecular Sciences · Lux, Alexander, Kahlert, Christoph, Grützmann, Robert et al.

    169 cited

19. Invasiveness of breast carcinoma cells and transcript profile: Eph receptors and ephrin ligands as molecular markers of potential diagnostic and prognostic application

    2004 · Biochemical and Biophysical Research Communications · Fox, Brian P, Kandpal, Raj P.

    166 cited

20. Diagnostic and Prognostic Molecular Markers for Renal Cell Carcinoma: A Critical Appraisal of the Current State of Research and Clinical Applicability

    2009 · European Urology · Eichelberg, Christian, Junker, Kerstin, Ljungberg, Börje et al.

    152 cited

21. Splenic marginal zone lymphoma: proposal of new diagnostic and prognostic markers identified after tissue and cDNA microarray analysis

    2005 · Blood · Ruíz-Ballesteros, Elena, Mollejo, Manuela, Rodríguez, Antonia et al.

    149 cited

22. Protein Glycosylation as a Diagnostic and Prognostic Marker of Chronic Inflammatory Gastrointestinal and Liver Diseases

    2019 · Gastroenterology · Verhelst, Xavier, Dias, Ana M., Colombel, Jean‐Frédéric et al.

    147 cited

23. Novel Glioblastoma Markers with Diagnostic and Prognostic Value Identified through Transcriptome Analysis

    2008 · Clinical Cancer Research · Reddy, Sreekanth P., Britto, Ramona, Vinnakota, Katyayni et al.

    146 cited

24. TRPM8 in prostate cancer cells: a potential diagnostic and prognostic marker with a secretory function?

    2006 · Endocrine Related Cancer · Zhang, Lei, Barritt, Greg J.

    137 cited

25. Anti-Sa antibody is an accurate diagnostic and prognostic marker in adult rheumatoid arthritis.

    1999 · PubMed · Hayem, Gilles, Chazerain, Pascal, Combe, Bernard et al.

    132 cited

26. Serum procalcitonin measurement as diagnostic and prognostic marker in febrile adult patients presenting to the emergency department

    2007 · Critical Care · Hausfater, Pierre, Juillien, Gaëlle, Madonna-Py, B. et al.

    131 cited

27. Intravoxel Incoherent Motion and Quantitative Non-Gaussian Diffusion MR Imaging: Evaluation of the Diagnostic and Prognostic Value of Several Markers of Malignant and Benign Breast Lesions

    2017 · Radiology · Iima, Mami, Kataoka, Masako, Kanao, Shotaro et al.

    130 cited

28. Human Heart-Type Fatty Acid-Binding Protein as an Early Diagnostic and Prognostic Marker in Acute Coronary Syndrome

    2003 · Cardiology · Nakata, Tomoaki, Hashimoto, Akiyoshi, Hase, Mamoru et al.

    129 cited

29. Serum Calprotectin: A Novel Diagnostic and Prognostic Marker in Inflammatory Bowel Diseases

    2016 · The American Journal of Gastroenterology · Kalla, Rahul, Kennedy, Nicholas A., Ventham, Nicholas T. et al.

    126 cited

30. Hematological and biochemical parameters as diagnostic and prognostic markers in SARS-COV-2 infected patients of Pakistan: a retrospective comparative analysis

    2021 · Hematology · Khalid, Atiqa, Jaffar, Muhammad Ali, Khan, Tabinda et al.

    122 cited