Most-cited papers on Efficacy and Formulation

Ranked by citation count via OpenAlex. Citations update on a rolling basis; list regenerates every 24h.

1. Clinical development of liposome based drugs: formulation, characterization, and therapeutic efficacy

   2011 · International Journal of Nanomedicine · Yeh, Ming‐Kung, Chang, Hsin‐I, Cheng, Ming−Yen

   789 cited

2. Amphotericin B Formulations: A Comparative Review of Efficacy and Toxicity

   2013 · Drugs · Hamill, Richard J.

   773 cited

3. Antifungal Susceptibility of<i>Candida</i>Biofilms: Unique Efficacy of Amphotericin B Lipid Formulations and Echinocandins

   2002 · Antimicrobial Agents and Chemotherapy · Kuhn, Duncan M., George, Tracy P., Chandra, J. et al.

   757 cited

4. In vivo evaluation of polymeric micellar paclitaxel formulation: toxicity and efficacy

   2001 · Journal of Controlled Release · Kim, Sung Chul, Kim, Dong Wook, Shim, Yong‐Ho et al.

   728 cited

5. Efficacy and Safely of a Topical Gel Formulation of Recombinant Human Platelet-Derived Growth Factor-BB (Becaplermin) in Patients With Chronic Neuropathic Diabetic Ulcers: A phase III randomized placebo-controlled double-blind study

   1998 · Diabetes Care · Wieman, T. Jeffery, Smiell, Janice M., Su, Yachin

   678 cited

6. Lipid Formulations of Amphotericin B: Clinical Efficacy and Toxicities

   1998 · Clinical Infectious Diseases · Wong‐Beringer, Annie, Jacobs, Robert A., Guglielmo, B. Joseph

   397 cited

7. Comparative Efficacy and Distribution of Lipid Formulations of Amphotericin B in Experimental<i>Candida albicans</i>Infection of the Central Nervous System

   2000 · The Journal of Infectious Diseases · Groll, Andreas H., Giri, Neelam, Petraitis, Vidmantas et al.

   370 cited

8. The pharmacology of palmitoylethanolamide and first data on the therapeutic efficacy of some of its new formulations

   2016 · British Journal of Pharmacology · Petrosino, Stefania, Marzo, Vincenzo Di

   323 cited

9. Prospective, Randomized, Double-Blind Study of the Efficacy and Tolerability of the Extended-Release Formulations of Oxybutynin and Tolterodine for Overactive Bladder: Results of the OPERA Trial

   2003 · Mayo Clinic Proceedings · Diokno, Ananias C., Appell, Rodney A., Sand, Peter K. et al.

   316 cited

10. Cholesterol-lowering efficacy of a microencapsulated bile salt hydrolase-active<i>Lactobacillus reuteri</i>NCIMB 30242 yoghurt formulation in hypercholesterolaemic adults

    2011 · British Journal Of Nutrition · Jones, Mitchell, Martoni, Christopher, Parent, Mathieu et al.

    314 cited

11. Efficacy and Safety of Vedolizumab Subcutaneous Formulation in a Randomized Trial of Patients With Ulcerative Colitis

    2019 · Gastroenterology · Sandborn, William J., Baert, Filip, Danese, Silvio et al.

    310 cited

12. Efficacy and safety of a targeted-release formulation of budesonide in patients with primary IgA nephropathy (NefIgArd): 2-year results from a randomised phase 3 trial

    2023 · The Lancet · Lafayette, Richard, Kristensen, Jens, Stone, Andrew et al.

    270 cited

13. Efficacy response of inhaled beclomethasone dipropionate in asthma is proportional to dose and is improved by formulation with a new propellant☆☆☆★

    1999 · Journal of Allergy and Clinical Immunology · Busse, William W., Brazinsky, Shari A., Jacobson, Kraig W. et al.

    261 cited

14. Safety and Efficacy of Chimeric Yellow Fever-Dengue Virus Tetravalent Vaccine Formulations in Nonhuman Primates

    2004 · Journal of Virology · Guirakhoo, Farshad, Пугачев, К. В., Zhang, Z. et al.

    253 cited

15. Development, Characterization, Efficacy and Mode of Action of Ambisome, A Unilamellar Liposomal Formulation of Amphotericin B

    1993 · Journal of Liposome Research · Adler‐Moore, Jill, Proffitt, Richard T.

    246 cited

16. Long-term safety and efficacy of a once-daily niacin/lovastatin formulation for patients with dyslipidemia**A complete list of participants in the Research Group and Publication Committee appears in the Appendix.

    2002 · The American Journal of Cardiology · Kashyap, Moti L., McGovern, Mark E., Berra, Kathleen et al.

    234 cited

17. Advances in nutraceutical delivery systems: From formulation design for bioavailability enhancement to efficacy and safety evaluation

    2018 · Trends in Food Science & Technology · Gonçalves, Raquel F.S., Martins, Joana T., Duarte, Catarina M.M. et al.

    234 cited

18. Coenzyme Q10 supplementation: Efficacy, safety, and formulation challenges

    2020 · Comprehensive Reviews in Food Science and Food Safety · Arenas‐Jal, Marta, Suñé‐Negre, Josep M., García‐Montoya, Encarna

    225 cited

19. Efficacy and Safety of a Once-Daily Morphine Formulation in Chronic, Moderate-to-Severe Osteoarthritis Pain

    2002 · Journal of Pain and Symptom Management · Caldwell, Jacques R., Rapoport, Ronald J., Davis, Jeffrey C. et al.

    222 cited

20. Efficacy and Safety of the 3-Month Formulation of Paliperidone Palmitate vs Placebo for Relapse Prevention of Schizophrenia

    2015 · JAMA Psychiatry · Berwaerts, Joris, Liu, Yanning, Gopal, Srihari et al.

    221 cited

21. Increased RNAi Efficacy in Spodoptera exigua via the Formulation of dsRNA With Guanylated Polymers

    2018 · Frontiers in Physiology · Christiaens, Olivier, Tardajos, Myriam G., Reyna, Zarel L. Martinez et al.

    212 cited

22. DYSBOT: A single‐blind, randomized parallel study to determine whether any differences can be detected in the efficacy and tolerability of two formulations of botulinum toxin type A—Dysport and Botox—assuming a ratio of 4:1

    1997 · Movement Disorders · Sampaio, Cristina, Ferreira, Joaquim J., Simões, Fernanda et al.

    207 cited

23. Efficacy and efficiency of new <i>Bacillus thuringiensis</i> var. <i>israelensis</i> and <i>Bacillus sphaericus</i> formulations against Afrotropical anophelines in Western Kenya

    2003 · Tropical Medicine & International Health · Fillinger, Ulrike, Knols, Bart GJ, Becker, Norbert

    206 cited

24. Paclitaxel and curcumin coadministration in novel cationic PEGylated niosomal formulations exhibit enhanced synergistic antitumor efficacy

    2018 · Journal of Nanobiotechnology · Alemi, Ashraf, Reza, Javad Zavar, Haghiralsadat, Fateme et al.

    192 cited

25. A new lipid emulsion formulation with high antimicrobial efficacy using chitosan

    2002 · European Journal of Pharmaceutics and Biopharmaceutics · Jumaa, Muhannad, Furkert, Franz H., Müller, Bernd W.

    186 cited

26. Efficacy of the New Long-Acting Formulation of Lanreotide (Lanreotide Autogel) in the Management of Acromegaly

    2002 · The Journal of Clinical Endocrinology & Metabolism · Caron, P., Beckers, Albert, Cullen, D. R. et al.

    185 cited

27. Advances in Controlled-Release Pesticide Formulations with Improved Efficacy and Targetability

    2021 · Journal of Agricultural and Food Chemistry · Li, Ningjun, Sun, Changjiao, Jiang, Jiajun et al.

    182 cited

28. Apomorphine for Parkinson’s Disease: Efficacy and Safety of Current and New Formulations

    2019 · CNS Drugs · Carbone, Federico, Djamshidian, Atbin, Seppi, Klaus et al.

    178 cited

29. Ultrasound-mediated Delivery of Paclitaxel for Glioma: A Comparative Study of Distribution, Toxicity, and Efficacy of Albumin-bound Versus Cremophor Formulations

    2019 · Clinical Cancer Research · Zhang, Daniel Y., Dmello, Crismita, Chen, Li et al.

    177 cited

30. Factors affecting the insecticidal efficacy of the diatomaceous earth formulation SilicoSec against adults and larvae of the confused flour beetle, Tribolium confusum DuVal (Coleoptera: Tenebrionidae)

    2004 · Crop Protection · Vayias, Basileios J., Athanassiou, Christos G.

    175 cited