Most-cited papers on Extracellular Vesicle Research Gaps

Ranked by citation count via OpenAlex. Citations update on a rolling basis; list regenerates every 24h.

1. Mapping bacterial extracellular vesicle research: insights, best practices and knowledge gaps

   2024 · Nature Communications · Langhe, Nele De, Dorpe, Sofie Van, Guilbert, Niké et al.

   43 cited

2. A perspective from the National Eye Institute Extracellular Vesicle Workshop: Gaps, needs, and opportunities for studies of extracellular vesicles in vision research

   2024 · Journal of Extracellular Vesicles · Lee, Sun Young, Klingeborn, Mikael, Bulte, Jeff W. M. et al.

   9 cited

3. Standardization of sample collection, isolation and analysis methods in extracellular vesicle research

   2013 · Journal of Extracellular Vesicles · Witwer, Kenneth W., Buzás, Edit I., Bemis, Lynne et al.

   2,398 cited

4. EV-TRACK: transparent reporting and centralizing knowledge in extracellular vesicle research

   2017 · Nature Methods · Deun, Jan Van, Mestdagh, Pieter, Agostinis, Patrizia et al.

   1,279 cited

5. Technologies and Standardization in Research on Extracellular Vesicles

   2020 · Trends in biotechnology · Gandham, Srujan, Su, Xianyi, Wood, Jacqueline et al.

   486 cited

6. Confounding factors of ultrafiltration and protein analysis in extracellular vesicle research

   2017 · Scientific Reports · Vergauwen, Glenn, Dhondt, Bert, Deun, Jan Van et al.

   271 cited

7. A call for Rigor and standardization in plant extracellular vesicle research

   2021 · Journal of Extracellular Vesicles · Pinedo, Marcela, Canal, Laura de la, Lousa, Carine De Marcos

   199 cited

8. Plasmonic Sensors for Extracellular Vesicle Analysis: From Scientific Development to Translational Research

   2020 · ACS Nano · Chin, L. K., Son, Taehwang, Hong, Jae‐Sang et al.

   128 cited

9. Extracellular vesicle-based drug overview: research landscape, quality control and nonclinical evaluation strategies

   2025 · Signal Transduction and Targeted Therapy · Xu, Gangling, Jin, Jing, Fu, Zhihao et al.

   128 cited

10. MIBlood‐EV: Minimal information to enhance the quality and reproducibility of blood extracellular vesicle research

    2023 · Journal of Extracellular Vesicles · Lucien, Fabrice, Gustafson, Dakota, Lenassi, Metka et al.

    122 cited

11. EVpedia: A community web resource for prokaryotic and eukaryotic extracellular vesicles research

    2015 · Seminars in Cell and Developmental Biology · Kim, Dae‐Kyum, Lee, Jae‐Wook, Simpson, Richard J. et al.

    115 cited

12. Extracellular vesicles as a source of prostate cancer biomarkers in liquid biopsies: a decade of research

    2021 · British Journal of Cancer · Ramírez‐Garrastacho, Manuel, Bajo-Santos, Cristina, Linē, Aija et al.

    115 cited

13. The protein and microRNA cargo of extracellular vesicles from parasitic helminths – current status and research priorities

    2020 · International Journal for Parasitology · Sotillo, Javier, Robinson, Mark W., Kimber, Michael J. et al.

    113 cited

14. Exosomes and Extracellular Vesicles as Emerging Theranostic Platforms in Cancer Research

    2020 · Cells · Ailuno, Giorgia, Baldassari, Sara, Lai, Francesco et al.

    88 cited

15. Growing pains: addressing the pitfalls of plant extracellular vesicle research

    2020 · New Phytologist · Rutter, Brian D., Innes, Roger W.

    86 cited

16. Reproducibility of extracellular vesicle research

    2022 · European Journal of Cell Biology · Nieuwland, Rienk, Siljander, Pia, Falcón‐Pérez, Juan Manuel et al.

    80 cited

17. A Novel Strategy to Increase the Yield of Exosomes (Extracellular Vesicles) for an Expansion of Basic Research

    2018 · Biological and Pharmaceutical Bulletin · Emam, Sherif E., Ando, Hidenori, Lila, Amr S. Abu et al.

    78 cited

18. The Impact of Extracellular Vesicle-Encapsulated Circulating MicroRNAs in Lung Cancer Research

    2014 · BioMed Research International · Fujita, Yu, Kuwano, Kazuyoshi, Ochiya, Takahiro et al.

    71 cited

19. Comparison of urinary extracellular vesicle isolation methods for transcriptomic biomarker research in diabetic kidney disease

    2020 · Journal of Extracellular Vesicles · Barreiro, Karina, Dwivedi, Om Prakash, Leparc, Germán et al.

    71 cited

20. Sphingolipid-Enriched Extracellular Vesicles and Alzheimer’s Disease: A Decade of Research

    2016 · Journal of Alzheimer s Disease · Dinkins, Michael B., Wang, Guanghu, Bieberich, Erhard

    70 cited

21. Rigor and standardization of extracellular vesicle research: Paving the road towards robustness

    2020 · Journal of Extracellular Vesicles · Nieuwland, Rienk, Falcón‐Pérez, Juan Manuel, Théry, Clotilde et al.

    70 cited

22. Comparing small urinary extracellular vesicle purification methods with a view to RNA sequencing—Enabling robust and non-invasive biomarker research

    2019 · Biomolecular Detection and Quantification · Mussack, Veronika, Wittmann, G., Pfaffl, Michael W.

    66 cited

23. Urinary extracellular vesicles: Assessment of pre‐analytical variables and development of a quality control with focus on transcriptomic biomarker research

    2021 · Journal of Extracellular Vesicles · Barreiro, Karina, Dwivedi, Om Prakash, Valkonen, Sami et al.

    60 cited

24. Extracellular Vesicles: A New Frontier for Research in Acute Respiratory Distress Syndrome

    2020 · American Journal of Respiratory Cell and Molecular Biology · Mahida, Rahul Y., Matsumoto, Shotaro, Matthay, Michael A.

    58 cited

25. Research progress on the role of extracellular vesicles in neurodegenerative diseases

    2023 · Translational Neurodegeneration · Li, Zhengzhe, Wang, Xiaoling, Wang, Xiaoxing et al.

    56 cited

26. Research progress of extracellular vesicles and exosomes derived from mesenchymal stem cells in the treatment of oxidative stress-related diseases

    2023 · Frontiers in Immunology · Zhang, Wenwen, Wang, Tingyu, Xue, Yuanye et al.

    55 cited

27. Comparative analysis of the minimal information for studies of extracellular vesicles guidelines: Advancements and implications for extracellular vesicle research

    2024 · Seminars in Cancer Biology · Vaiaki, Elisavet Maria, Falasca, Marco

    53 cited

28. Removal of platelets from blood plasma to improve the quality of extracellular vesicle research

    2022 · Journal of Thrombosis and Haemostasis · Bettin, Britta, Gąsecka, Aleksandra, Li, Bo et al.

    52 cited

29. Advanced research on extracellular vesicles based oral drug delivery systems

    2022 · Journal of Controlled Release · Song, Mengdi, Cui, Mingxiao, Fang, Zhou et al.

    48 cited

30. Consensus statement on research and application of Chinese herbal medicine derived extracellular vesicles-like particles (2023 edition)

    2023 · Chinese Herbal Medicines · Zhao, Qing, Wang, Tong, Wang, Hongbin et al.

    48 cited