Most-cited papers on Pharmacological Evaluation

Ranked by citation count via OpenAlex. Citations update on a rolling basis; list regenerates every 24h.

1. Drug Discovery and Evaluation: Pharmacological Assays

   2014 · 1946-, Hock, Franz Jakob

   1,421 cited

2. An evaluation of R2 as an inadequate measure for nonlinear models in pharmacological and biochemical research: a Monte Carlo approach

   2010 · BMC Pharmacology · Spiess, Andrej‐Nikolai, Neumeyer, Natalie

   943 cited

3. A clinical-pharmacological evaluation of hepatic arterial infusions of 5-fluoro-2'-deoxyuridine and 5-fluorouracil.

   1978 · PubMed · Ensminger, William D., Rosowsky, A., Raso, Vic et al.

   524 cited

4. Preclinical pharmacologic evaluation of geldanamycin as an antitumor agent

   1995 · Cancer Chemotherapy and Pharmacology · Supko, Jeffrey G., Hickman, Robert L., Grever, Michael R. et al.

   494 cited

5. Sobol Sensitivity Analysis: A Tool to Guide the Development and Evaluation of Systems Pharmacology Models

   2015 · CPT Pharmacometrics & Systems Pharmacology · Zhang, X‐Y, Trame, MN, Lesko, LJ et al.

   462 cited

6. PHARMACOLOGICAL ESTIMATION OF DRUG-RECEPTOR DISSOCIATION CONSTANTS. STATISTICAL EVALUATION. I. AGONISTS

   1971 · Journal of Pharmacology and Experimental Therapeutics · Parker, Robert B., Waud, D. R.

   446 cited

7. The role of technical, biological and pharmacological factors in the laboratory evaluation of anticonvulsant drugs. III. Pentylenetetrazole seizure models

   1991 · Epilepsy Research · Löscher, Wolfgang, Hönack, Dagmar, Fassbender, C. P. et al.

   404 cited

8. Pharmacological Evaluation of Cannabinoid Receptor Ligands in a Mouse Model of Anxiety: Further Evidence for an Anxiolytic Role for Endogenous Cannabinoid Signaling

   2006 · Journal of Pharmacology and Experimental Therapeutics · Patel, Sachin, Hillard, Cecilia J.

   391 cited

9. Pharmacological and clinical evaluation of l-asparaginase in the treatment of leukemia

   2006 · Critical Reviews in Oncology/Hematology · Narta, Umesh Kumar, Kanwar, Shamsher S., Azmi, Wamik

   384 cited

10. Mechanistic Investigations of the Mitochondrial Complex I Inhibitor Rotenone in the Context of Pharmacological and Safety Evaluation

    2017 · Scientific Reports · Heinz, Sabrina, Freyberger, Alexius, Lawrenz, Bettina et al.

    321 cited

11. Selection, preparation and pharmacological evaluation of plant material

    1997 · General Pharmacology The Vascular System

    316 cited

12. Lipopolysaccharide-induced changes in plasma nitrite and nitrate concentrations in rats and mice: pharmacological evaluation of nitric oxide synthase inhibitors.

    1995 · Journal of Pharmacology and Experimental Therapeutics · Tracey, W. Ross, Tse, Jenny, Carter, G

    310 cited

13. α-Linolenic acid: Nutraceutical, pharmacological and toxicological evaluation

    2014 · Food and Chemical Toxicology · Kim, Kyu‐Bong, Nam, Yoon A, Kim, Hyung Sik et al.

    307 cited

14. Synthesis and pharmacological evaluation of some 3-phenyl-2-substituted-3H-quinazolin-4-one as analgesic, anti-inflammatory agents

    2006 · Bioorganic & Medicinal Chemistry · Alagarsamy, V., Solomon, V. Raja, Dhanabal, K.

    278 cited

15. Dihydropyridines: evaluation of their current and future pharmacological applications

    2009 · Drug Discovery Today · Edraki, Najmeh, Mehdipour, Ahmad Reza, Khoshneviszadeh, Mehdi et al.

    272 cited

16. Current Evaluation of the Millennium Phytomedicine- Ginseng (II): Collected Chemical Entities, Modern Pharmacology, and Clinical Applications Emanated from Traditional Chinese Medicine

    2009 · Current Medicinal Chemistry · Jia, Lee, Zhao, Yuqing, Liang, Xing‐Jie

    270 cited

17. Preliminary pharmacologic and clinical evaluation of camptothecin sodium (NSC-100880).

    1970 · PubMed · Ja, Gottlieb, Am, Guarino, Jb, Call et al.

    250 cited

18. Pharmacological Evaluation of the Anti-inflammatory Activity of a Citrus Bioflavonoid, Hesperidin, and the Isoflavonoids, Duartin and Claussequinone, in Rats and Mice

    1994 · Journal of Pharmacy and Pharmacology · Emim, José Artur da Silva, Oliveira, Alaı́de Braga de, Lapa, Antônio José

    249 cited

19. Pharmacological evaluation of novel Alzheimer's disease therapeutics: acetylcholinesterase inhibitors related to galanthamine.

    1996 · Journal of Pharmacology and Experimental Therapeutics · Bores, Gina M., Huger, Francis P., Petko, Wayne W. et al.

    248 cited

20. Synthesis and pharmacological evaluation of pyrazoline derivatives as new anti-inflammatory and analgesic agents

    2008 · Bioorganic & Medicinal Chemistry Letters · Amir, Mohd, Kumar, Harish, Khan, Suroor A.

    244 cited

21. Coptidis rhizoma and its main bioactive components: recent advances in chemical investigation, quality evaluation and pharmacological activity

    2018 · Chinese Medicine · Meng, Fancheng, Wu, Zheng-Feng, Yin, Zhi‐Qi et al.

    244 cited

22. Evaluation of the Causes and Accuracy of Pharmacologic Localization in Horner's Syndrome

    1980 · American Journal of Ophthalmology · Maloney, William F., Younge, Brian R., Moyer, Norma J.

    235 cited

23. The potential of anti-malarial compounds derived from African medicinal plants. Part I: A pharmacological evaluation of alkaloids and terpenoids

    2013 · Malaria Journal · Onguéné, Pascal Amoa, Ntie‐Kang, Fidele, Lifongo, Lydia L. et al.

    231 cited

24. Evaluation of pharmacological activities and assessment of intraocular penetration of an ayurvedic polyherbal eye drop (Itone™) in experimental models

    2013 · BMC Complementary and Alternative Medicine · Velpandian, Thirumurthy, Gupta, Pankaj, Ravi, Alok Kumar et al.

    228 cited

25. Network Pharmacology Evaluation Method Guidance - Draft

    2021 · World Journal of Traditional Chinese Medicine · Li, Shao

    223 cited

26. Integrating Network Pharmacology and Pharmacological Evaluation for Deciphering the Action Mechanism of Herbal Formula Zuojin Pill in Suppressing Hepatocellular Carcinoma

    2019 · Frontiers in Pharmacology · Guo, Wei, Huang, Jihan, Wang, Ning et al.

    217 cited

27. Photochemical and pharmacological evaluation of 7-nitroindolinyl-and 4-methoxy-7-nitroindolinyl-amino acids as novel, fast caged neurotransmitters

    2001 · Journal of Neuroscience Methods · Canepari, Marco, Nelson, Lawrence M., Papageorgiou, George et al.

    215 cited

28. Pharmacological evaluation of a new Ca2+ antagonist, 8-(N,N-diethylamino)-octyl-3,4,5-trimethoxybenzoate hydrochloride (TMB-8): Studies in smooth muscles

    1974 · European Journal of Pharmacology · Malagodi, Marjorie H., Chiou, C.Y.

    214 cited

29. Design, synthesis, and pharmacological evaluation of ultrashort- to long-acting opioid analgesics

    1991 · Journal of Medicinal Chemistry · Feldman, Paul L., James, McKerrow, Brackeen, Marcus F. et al.

    204 cited