Most-cited papers on Scalability of Industrial Production

Ranked by citation count via OpenAlex. Citations update on a rolling basis; list regenerates every 24h.

1. Industrial choices for protein production by large-scale cell culture

   2001 · Current Opinion in Biotechnology · Chu, Lily, Robinson, David K.

   547 cited

2. Carbon-negative production of acetone and isopropanol by gas fermentation at industrial pilot scale

   2022 · Nature Biotechnology · Liew, Fungmin, Nogle, Robert, Abdalla, Tanus et al.

   467 cited

3. Industrial-Scale Production and Applications of Bacterial Cellulose

   2020 · Frontiers in Bioengineering and Biotechnology · Zhong, Chunyan

   351 cited

4. CO2-based methanol and DME – Efficient technologies for industrial scale production

   2011 · Catalysis Today · Pontzen, F., Liebner, Waldemar, Gronemann, Veronika et al.

   350 cited

5. A process model to estimate the cost of industrial scale biodiesel production from waste cooking oil by supercritical transesterification

   2006 · Resources Conservation and Recycling · Kasteren, J.M.N. van, Nisworo, A.P.

   300 cited

6. Industrial scale production of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate)

   2001 · Applied Microbiology and Biotechnology · Chen, Gang, Zhang, G., Park, Sanghoo et al.

   294 cited

7. Cost evaluation of cellulase enzyme for industrial-scale cellulosic ethanol production based on rigorous Aspen Plus modeling

   2015 · Bioprocess and Biosystems Engineering · Liu, Gang, Zhang, Jian, Bao, Jie

   282 cited

8. Bifunctional ionomers for efficient co-electrolysis of CO2 and pure water towards ethylene production at industrial-scale current densities

   2022 · Nature Energy · Li, Wenzheng, Yin, Zhenglei, Gao, Zeyu et al.

   268 cited

9. Industrial scale production of fibre batteries by a solution-extrusion method

   2022 · Nature Nanotechnology · Liao, Meng, Wang, Chuang, Hong, Yang et al.

   231 cited

10. Scale-up concept of single-channel microreactors from process development to industrial production

    2010 · Chemical Engineering Journal · Kockmann, Norbert, Gottsponer, Michael, Roberge, Dominique M.

    227 cited

11. Industrial scale production of plasmid DNA for vaccine and gene therapy: plasmid design, production, and purification

    2003 · Enzyme and Microbial Technology · Prather, Kristala Jones, Sagar, Sangeetha L., Murphy, Jason C. et al.

    221 cited

12. An overview of industrial scalable production of graphene oxide and analytical approaches for synthesis and characterization

    2020 · Journal of Materials Research and Technology · Ikram, Rabia, Jan, Badrul Mohamed, Ahmad, Waqas

    220 cited

13. Brick production with dredged harbour sediments. An industrial-scale experiment

    2002 · Waste Management · Hamer, Kay, Karius, Volker

    213 cited

14. Interpretable machine learning for predicting biomethane production in industrial-scale anaerobic co-digestion

    2019 · The Science of The Total Environment · Clercq, Djavan De, Wen, Zongguo, Fan, Fei et al.

    206 cited

15. Production of bio-ethanol from soybean molasses by Saccharomyces cerevisiae at laboratory, pilot and industrial scales

    2008 · Bioresource Technology · Siqueira, Paula F., Karp, Susan Grace, Carvalho, Júlio César de et al.

    206 cited

16. Predicting the environmental impact of a future nanocellulose production at industrial scale: Application of the life cycle assessment scale-up framework

    2017 · Journal of Cleaner Production · Piccinno, Fabiano, Hischier, Roland, Seeger, Stefan et al.

    189 cited

17. Industrial-scale steam explosion pretreatment of sugarcane straw for enzymatic hydrolysis of cellulose for production of second generation ethanol and value-added products

    2012 · Bioresource Technology · Oliveira, Fernando Moreira Vasconcelos de, Pinheiro, Irapuan Oliveira, Souto-Maior, Ana Maria et al.

    188 cited

18. Industrial Scale-Up of pH-Controlled Liquid Hot Water Pretreatment of Corn Fiber for Fuel Ethanol Production

    2005 · Applied Biochemistry and Biotechnology · Mosier, Nathan S., Hendrickson, Richard, Brewer, Mark et al.

    180 cited

19. Toward Industrial-Scale Production of Perovskite Solar Cells: Screen Printing, Slot-Die Coating, and Emerging Techniques

    2018 · The Journal of Physical Chemistry Letters · Rong, Yaoguang, Ming, Yue, Ji, Wenxian et al.

    172 cited

20. Scalable Production and Isolation of Extracellular Vesicles: Available Sources and Lessons from Current Industrial Bioprocesses

    2019 · Biotechnology Journal · Paganini, Carolina, Palmiero, Umberto Capasso, Pòcsfalvi, Gabriella et al.

    151 cited

21. Enrichment of Plasticicumulans acidivorans at pilot-scale for PHA production on industrial wastewater

    2014 · Journal of Biotechnology · Tamis, Jelmer, Lužkov, Kätlin, Jiang, Yang et al.

    150 cited

22. Application of simultaneous saccharification and fermentation (SSF) from viscosity reducing of raw sweet potato for bioethanol production at laboratory, pilot and industrial scales

    2011 · Bioresource Technology · Zhang, Liang, Zhao, Hai, Gan, Mingzhe et al.

    144 cited

23. Use of recycled concrete aggregates from precast block for the production of new building blocks: An industrial scale study

    2020 · Resources Conservation and Recycling · Zhao, Zengfeng, Courard, Luc, Groslambert, Sylvie et al.

    140 cited

24. Engineering microbial cell factories for the production of plant natural products: from design principles to industrial-scale production

    2017 · Microbial Cell Factories · Liu, Xiaonan, Ding, Wentao, Jiang, Huifeng

    139 cited

25. Large-Scale Selection and Breeding To Generate Industrial Yeasts with Superior Aroma Production

    2014 · Applied and Environmental Microbiology · Steensels, Jan, Meersman, Esther, Snoek, Tim et al.

    136 cited

26. Production Scheduling of a Large-Scale Industrial Batch Plant. II. Reactive Scheduling

    2006 · Industrial & Engineering Chemistry Research · Janak, Stacy L., Floudas, Christodoulos A., Kallrath, Josef et al.

    135 cited

27. Large-scale droplet production in microfluidic devices—an industrial perspective

    2013 · Journal of Physics D Applied Physics · Holtze, Christian

    126 cited

28. Machine learning powered software for accurate prediction of biogas production: A case study on industrial-scale Chinese production data

    2019 · Journal of Cleaner Production · Clercq, Djavan De, Jalota, Devansh, Shang, Ruoxi et al.

    123 cited

29. Scale-Up of Photochemical Reactions: Transitioning from Lab Scale to Industrial Production

    2023 · Annual Review of Chemical and Biomolecular Engineering · Zondag, Stefan D. A., Mazzarella, Daniele, Noël, Timothy

    122 cited

30. An industrial scale multiple supercritical carbon dioxide apparatus and its eco-friendly dyeing production

    2016 · Journal of CO2 Utilization · Zheng, Huanda, Zhang, Juan, Yan, Jun et al.

    121 cited