Most-cited papers on clinical translation patients therapeutic interventions

Ranked by citation count via OpenAlex. Citations update on a rolling basis; list regenerates every 24h.

1. Why clinical trial outcomes fail to translate into benefits for patients

   2017 · Trials · Heneghan, Carl, Goldacre, Ben, Mahtani, Kamal R

   420 cited

2. Translating Patient‐Oriented Eczema Measure ( <scp>POEM</scp> ) scores into clinical practice by suggesting severity strata derived using anchor‐based methods

   2013 · British Journal of Dermatology · Charman, Carolyn, Venn, Andrea, Ravenscroft, Jane et al.

   287 cited

3. Prospective pan-cancer germline testing using MSK-IMPACT informs clinical translation in 751 patients with pediatric solid tumors

   2021 · Nature Cancer · Fiala, Elise, Jayakumaran, Gowtham, Mauguen, Audrey et al.

   164 cited

4. Resveratrol and inflammation: Challenges in translating pre-clinical findings to improved patient outcomes

   2015 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · Poulsen, Morten Møller, Fjeldborg, Karen, Ørnstrup, Marie Juul et al.

   130 cited

5. The development of a clinical management algorithm for early physical activity and mobilization of critically ill patients: synthesis of evidence and expert opinion and its translation into practice

   2011 · Clinical Rehabilitation · Hanekom, Susan, Gosselink, Rik, Dean, Elizabeth et al.

   129 cited

6. Early Mobilization of Patients in Intensive Care: Organization, Communication and Safety Factors that Influence Translation into Clinical Practice

   2018 · Critical Care · Hodgson, Carol, Capell, Elizabeth, Tipping, Claire J.

   118 cited

7. Translating the Science of Patient-Reported Outcomes Assessment Into Clinical Practice

   2007 · JNCI Monographs · Osoba, David

   111 cited

8. Pain relief in a neuropathy patient by lacosamide: Proof of principle of clinical translation from patient-specific iPS cell-derived nociceptors

   2018 · EBioMedicine · Namer, Barbara, Schmidt, Diana, Eberhardt, Esther et al.

   107 cited

9. Quantifying the clinical virulence of Klebsiella pneumoniae producing carbapenemase Klebsiella pneumoniae with a Galleria mellonellamodel and a pilot study to translate to patient outcomes

   2014 · BMC Infectious Diseases · McLaughlin, Milena M., Advincula, Maria R., Malczynski, Michael et al.

   95 cited

10. Incidence and clinical significance of hepatitis B virus precore gene translation initiation mutations in e antigen‐negative patients

    1998 · Journal of Viral Hepatitis · Laras, A., Koskinas, John, Avgidis, K. et al.

    94 cited

11. Patient-mediated knowledge translation (PKT) interventions for clinical encounters: a systematic review

    2015 · Implementation Science · Gagliardi, Anna R., Légaré, France, Brouwers, Melissa et al.

    93 cited

12. From patient-specific induced pluripotent stem cells to clinical translation in long QT syndrome Type 2

    2019 · European Heart Journal · Schwartz, Peter J., Gnecchi, Massimiliano, Dagradi, Federica et al.

    88 cited

13. Clinical translation of a patient-specific scaffold-guided bone regeneration concept in four cases with large long bone defects

    2022 · Journal of Orthopaedic Translation · Laubach, Markus, Suresh, Sinduja, Herath, Buddhi et al.

    88 cited

14. Clinical translation of patient-derived tumour organoids- bottlenecks and strategies

    2022 · Biomarker Research · Foo, Malia Alexandra, You, Ming, Chan, Shing Leng et al.

    82 cited

15. ASAS40 and ASDAS clinical responses in the ABILITY-1 clinical trial translate to meaningful improvements in physical function, health-related quality of life and work productivity in patients with non-radiographic axial spondyloarthritis

    2015 · Lara D. Veeken · Heijde, Désirée van der, Joshi, Avani, Pangan, Aileen L. et al.

    66 cited

16. Evaluation of Serum Trace Element Levels and Superoxide Dismutase Activity in Patients with Inflammatory Bowel Disease: Translating Basic Research into Clinical Application

    2016 · Biological Trace Element Research · Mohammadi, Erfan, Qujeq, Durdi, Taheri, Hassan et al.

    65 cited

17. Integrating Image-Based Design and 3D Biomaterial Printing To Create Patient Specific Devices within a Design Control Framework for Clinical Translation

    2016 · ACS Biomaterials Science & Engineering · Hollister, Scott J., Flanagan, Colleen L., Morrison, R. J. et al.

    62 cited

18. How to translate clinical trial results into gain in healthy life expectancy for individual patients

    2016 · BMJ · Dorresteijn, Jannick A N, Kaasenbrood, Lotte, Cook, Nancy R. et al.

    61 cited

19. Patient‐centered, evidence‐based, and cost‐conscious cancer care across the continuum: Translating the Institute of Medicine report into clinical practice

    2014 · CA A Cancer Journal for Clinicians · Nekhlyudov, Larissa, Levit, Laura A., Hurria, Arti et al.

    58 cited

20. Translating Scientific Advancement into Clinical Benefit for Castration-Resistant Prostate Cancer Patients

    2011 · Clinical Cancer Research · Attard, Gerhardt, Bono, Johann S. de

    52 cited

21. Quantification of dynamic posterior translation in modified bilateral Alexander views and correlation with clinical and radiological parameters in patients with acute acromioclavicular joint instability

    2017 · Archives of Orthopaedic and Trauma Surgery · Minkus, Marvin, Hann, Carmen, Scheibel, Markus et al.

    51 cited

22. Clinical Translation and Validation of a Predictive Biomarker for Patritumab, an Anti-human Epidermal Growth Factor Receptor 3 (HER3) Monoclonal Antibody, in Patients With Advanced Non-small Cell Lung Cancer

    2015 · EBioMedicine · Mendell, Jeanne, Freeman, Daniel J., Feng, Wenqin et al.

    49 cited

23. Translation and validation of the Korean version of the clinical frailty scale in older patients

    2021 · BMC Geriatrics · Ko, Ryoung‐Eun, Moon, Seong Mi, Kang, Danbee et al.

    39 cited

24. Translating clinical and patient-reported data to tailored shared decision reports with predictive analytics for knee and hip arthritis

    2020 · Quality of Life Research · Franklin, Patricia D., Zheng, Hua, Bond, Christina et al.

    38 cited

25. A non-randomized clinical control trial of Harrison mirror image methods for correcting trunk list (lateral translations of the thoracic cage) in patients with chronic low back pain

    2004 · European Spine Journal · Harrison, Deed E., Cailliet, René, Betz, Joseph W. et al.

    37 cited

26. Understanding the place for <scp>GLP‐1RA</scp> therapy: Translating guidelines for treatment of type 2 diabetes into everyday clinical practice and patient selection

    2021 · Diabetes Obesity and Metabolism · Andreasen, Christine R., Andersen, Andreas, Knop, Filip K. et al.

    36 cited

27. Developing theory-informed knowledge translation strategies to facilitate the use of patient-reported outcome measures in interdisciplinary low back pain clinical practices in Quebec: mixed methods study

    2020 · BMC Health Services Research · Eilayyan, Owis, Visca, Regina, Zidarov, Diana et al.

    36 cited

28. Shift in translations: Data work with patient-generated health data in clinical practice

    2019 · Health Informatics Journal · Íslind, Anna Sigríður, Lindroth, Tomas, Lundin, Johan et al.

    35 cited

29. Clinical translation of 177Lu-labeled PSMA-617: Initial experience in prostate cancer patients

    2016 · Nuclear Medicine and Biology · Das, Tapas, Guleria, Mohini, Parab, Anil et al.

    34 cited

30. Every urologist and oncologist should know about treating sexual and gender minority prostate cancer patients: translating research findings into clinical practice

    2021 · Translational Andrology and Urology · Rosser, B. R. Simon, Rider, G. Nic, Kapoor, Aditya et al.

    30 cited