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Most-cited papers on concentration dose cell concentrations viability

Ranked by citation count via OpenAlex. Citations update on a rolling basis; list regenerates every 24h.

Dose- and time-dependent effect of high glucose concentration on viability of notochordal cells and expression of matrix degrading and fibrotic enzymes
2013 · International Orthopaedics · Park, Eun‐Young, Park, Jong-Beon
50 cited
Histone Deacetylase Inhibitor Romidepsin Induces HIV Expression in CD4 T Cells from Patients on Suppressive Antiretroviral Therapy at Concentrations Achieved by Clinical Dosing
2014 · PLoS Pathogens · Wei, Datsen G., Chiang, Vicki, Fyne, Elizabeth et al.
280 cited
Lycopene and<i>β</i>-carotene protect against oxidative damage in HT29 cells at low concentrations but rapidly lose this capacity at higher doses
1999 · Free Radical Research · Lowe, Gordon, Booth, Laurence, Young, Andrew et al.
208 cited
Dose-dependent cell growth in response to concentration modulated patterns of FGF-2 printed on fibrin
2005 · Biomaterials · Miller, Eric D., Fisher, Gregory W., Weiss, Lee E. et al.
114 cited
The bimodal effect of interleukin 1 on rat pancreatic beta-cells – stimulation followed by inhibition – depends upon dose, duration of exposure, and ambient glucose concentration
1988 · European Journal of Endocrinology · Spinas, Giatgen A., Palmer, Jerry P., Mandrup‐Poulsen, Thomas et al.
100 cited
Dose-Dependent ATP Depletion and Cancer Cell Death following Calcium Electroporation, Relative Effect of Calcium Concentration and Electric Field Strength
2015 · PLoS ONE · Hansen, Emilie Louise, Sözer, Esin B., Romeo, Stefania et al.
95 cited
Phase II Study of Area Under the Plasma-Concentration-Versus-Time Curve–Based Carboplatin Plus Standard-Dose Intravenous Etoposide in Elderly Patients With Small-Cell Lung Cancer
1999 · Journal of Clinical Oncology · Okamoto, Hiroaki, Watanabe, Koshiro, Nishiwaki, Yutaka et al.
90 cited
Recombinant Human Thrombopoietin in Combination With Granulocyte Colony-Stimulating Factor Enhances Mobilization of Peripheral Blood Progenitor Cells, Increases Peripheral Blood Platelet Concentration, and Accelerates Hematopoietic Recovery Following High-Dose Chemotherapy
1999 · Blood · Somlo, George, Sniecinski, Irena, Veer, Anna ter et al.
85 cited
Low dose ionizing radiation produces too few reactive oxygen species to directly affect antioxidant concentrations in cells
2012 · Biology Letters · Smith, J.T., Willey, Neil, Hancock, John T.
80 cited
High dose concentration administration of ascorbic acid inhibits tumor growth in BALB/C mice implanted with sarcoma 180 cancer cells via the restriction of angiogenesis
2009 · Journal of Translational Medicine · Yeom, Chang‐Hwan, Lee, Gunsup, Park, Jin‐Hee et al.
80 cited
Microfluidic Serial Dilution Cell-Based Assay for Analyzing Drug Dose Response over a Wide Concentration Range
2010 · Analytical Chemistry · Sugiura, Shinji, Hattori, Koji, Kanamori, Toshiyuki
78 cited
Exposure of aerosols and nanoparticle dispersions to in vitro cell cultures: A review on the dose relevance of size, mass, surface and concentration
2010 · Journal of Aerosol Science · Grass, Robert N., Limbach, Ludwig K., Athanassiou, Evagelos K. et al.
57 cited
Late dosing with ethacrynic acid can reduce gentamicin concentration in perilymph and protect cochlear hair cells
2003 · Hearing Research · Ding, Dalian, McFadden, Sandra L., Browne, Richard W. et al.
44 cited
Manipulation of prothrombin concentration improves response to high‐dose factor VIIa in a cell‐based model of haemophilia
2006 · British Journal of Haematology · Allen, Geoffrey, Hoffman, Maureane, Roberts, Harold R. et al.
40 cited
Interindividual differences in chlorthalidone concentration in plasma and red cells of man after single and multiple doses
1976 · European Journal of Clinical Pharmacology · Collste, P., Garle, Mats, Rawlins, M. D. et al.
37 cited
Concentrations of cyclosporin A and FK506 that inhibit IL-2 induction in human T cells do not affect TGF-β1 biosynthesis, whereas higher doses of cyclosporin A trigger apoptosis and release of preformed TGF-β1
2005 · Journal of Leukocyte Biology · Minguillón, Jordi, Morancho, Beatriz, Kim, Seong‐Jin et al.
37 cited
Variability of voriconazole concentrations in patients with hematopoietic stem cell transplantation and hematological malignancies: influence of loading dose, procalcitonin, and pregnane X receptor polymorphisms
2020 · European Journal of Clinical Pharmacology · Zeng, Guangting, Wang, Linlin, Shi, Lihong et al.
35 cited
Impact of CYP3A5, POR, and CYP2C19 Polymorphisms on Trough Concentration to Dose Ratio of Tacrolimus in Allogeneic Hematopoietic Stem Cell Transplantation
2019 · International Journal of Molecular Sciences · Suetsugu, Kimitaka, Mori, Yasuo, Yamamoto, Nanae et al.
35 cited
Pharmacokinetics and Buccal Mucosal Concentrations of a 15 Milligram per Kilogram of Body Weight Total Dose of Liposomal Amphotericin B Administered as a Single Dose (15 mg/kg), Weekly Dose (7.5 mg/kg), or Daily Dose (1 mg/kg) in Peripheral Stem Cell Transplant Patients
2009 · Antimicrobial Agents and Chemotherapy · Gubbins, Paul O., Amsden, Jarrett R., McConnell, Scott A. et al.
33 cited
Repeat and single dose administration of gadodiamide to rats to investigate concentration and location of gadolinium and the cell ultrastructure
2021 · Scientific Reports · Davies, Julie, Marino, Michael, Smith, Adrian et al.
32 cited
A low dose of ethidium bromide leads to an increase of total mitochondrial DNA while higher concentrations induce the mtDNA 4997 deletion in a human neuronal cell line
2006 · Mutation research. Fundamental and molecular mechanisms of mutagenesis · Wurmb‐Schwark, Nicole von, Cavelier, Lucia, Cortopassi, Gino
30 cited
Environmentally Relevant Concentrations of Arsenite Induce Dose-Dependent Differential Genotoxicity Through Poly(ADP-Ribose) Polymerase Inhibition and Oxidative Stress in Mouse Thymus Cells
2015 · Toxicological Sciences · Xu, Huan, Zhou, Xixi, Xia, Wen et al.
28 cited
Low dose calcium heparin in horses: plasma heparin concentrations, effects on red blood cell mass and on coagulation variables
1991 · Equine Veterinary Journal · Gerhards, H
27 cited
In vitro biokinetics of chlorpromazine and the influence of different dose metrics on effect concentrations for cytotoxicity in Balb/c 3T3, Caco-2 and HepaRG cell cultures
2013 · Toxicology in Vitro · Broeders, Jessica J.W., Blaauboer, Bas J., Hermens, Joop L. M.
26 cited
Estimating the concentration of therapeutic range using disease-specific iPS cells: Low-dose rapamycin therapy for Pendred syndrome
2018 · Regenerative Therapy · Hosoya, Makoto, Saeki, Tsubasa, Saegusa, Chika et al.
24 cited
Methylene blue and photodynamic therapy for melanomas: Inducing different rates of cell death (necrosis and apoptosis) in B16-F10 melanoma cells according to methylene blue concentration and energy dose
2021 · Photodiagnosis and Photodynamic Therapy · Grande, Murilo Penteado Del, Miyake, Andréa Midory, Nagamine, Márcia Kazumi et al.
24 cited
Correction: Dose-Dependent ATP Depletion and Cancer Cell Death following Calcium Electroporation, Relative Effect of Calcium Concentration and Electric Field Strength
2015 · PLoS ONE · Hansen, Emilie Louise, Sözer, Esin B., Romeo, Stefania et al.
22 cited
Cell killing by the novel imidazoacridinone antineoplastic agent, C-1311, is inhibited at high concentrations coincident with dose-differentiated cell cycle perturbation
1996 · British Journal of Cancer · Lamb, Justin, Wheatley, DN
20 cited
Photodynamic toxicity of porphyrins and chlorins for a human tumor cell line: Combined light and concentration dose responses for the retained fraction
1988 · Biochemical and Biophysical Research Communications · Nourse, W.Logan, Parkhurst, R. M., Skinner, W. A. et al.
19 cited
A Phase I study of the combined hypoxic cell radiosensitisers, Ro 03–8799 and SR 2508: a preliminary report of single-dose toxicity, pharmacokinetics and tumour concentrations
1986 · British Journal of Radiology · Newman, H, Bleehen, Norman M., Workman, Paul
19 cited