Most-cited papers on controlled randomized trials trial pilot

Ranked by citation count via OpenAlex. Citations update on a rolling basis; list regenerates every 24h.

1. A Pilot Study and Randomized Controlled Trial of the Mindful Self‐Compassion Program

   2012 · Journal of Clinical Psychology · Neff, Kristin D., Germer, Christopher K.

   2,149 cited

2. Randomized, Double-Blind, Placebo-Controlled, Pilot Trial of Infliximab, a Chimeric Monoclonal Antibody to Tumor Necrosis Factor-α, in Patients With Moderate-to-Severe Heart Failure

   2003 · Circulation · Chung, Eugene S., Packer, Milton, Lo, Kim Hung et al.

   1,625 cited

3. Adherence to a Smartphone Application for Weight Loss Compared to Website and Paper Diary: Pilot Randomized Controlled Trial

   2013 · Journal of Medical Internet Research · Carter, Michelle C., Burley, V. J., Nykjaer, Camilla et al.

   706 cited

4. Meaning‐centered group psychotherapy for patients with advanced cancer: a pilot randomized controlled trial

   2009 · Psycho-Oncology · Breitbart, William, Rosenfeld, Barry, Gibson, C. G. et al.

   690 cited

5. Task-related circuit training improves performance of locomotor tasks in chronic stroke: A randomized, controlled pilot trial

   2000 · Archives of Physical Medicine and Rehabilitation · Dean, Catherine M., Richards, Carol L., Malouin, Francine

   667 cited

6. Six-Month Randomized, Placebo-Controlled, Double-Blind, Pilot Clinical Trial of Curcumin in Patients With Alzheimer Disease

   2008 · Journal of Clinical Psychopharmacology · Baum, Larry, Lam, Christopher Wai Kei, Cheung, Stanley K. K. et al.

   584 cited

7. Goal-directed fluid management based on pulse pressure variation monitoring during high-risk surgery: a pilot randomized controlled trial

   2007 · Critical Care · Lopes, Marcel Rezende, Oliveira, Marcos Antônio de, Pereira, Vanessa Oliveira Silva et al.

   453 cited

8. Pilot Randomized Controlled Trial of Individual Meaning-Centered Psychotherapy for Patients With Advanced Cancer

   2012 · Journal of Clinical Oncology · Breitbart, William, Poppito, Shannon R., Rosenfeld, Barry et al.

   418 cited

9. Randomized, controlled pilot trial of a smartphone app for smoking cessation using acceptance and commitment therapy

   2014 · Drug and Alcohol Dependence · Bricker, Jonathan B., Mull, Kristin E., Kientz, Julie A. et al.

   395 cited

10. Dialectical behavior therapy skills for transdiagnostic emotion dysregulation: A pilot randomized controlled trial

    2014 · Behaviour Research and Therapy · Neacsiu, Andrada D., Eberle, Jeremy William, Kramer, Rachel et al.

    391 cited

11. A pilot randomized controlled trial of Dialectical Behavior Therapy with and without the Dialectical Behavior Therapy Prolonged Exposure protocol for suicidal and self-injuring women with borderline personality disorder and PTSD

    2014 · Behaviour Research and Therapy · Harned, Melanie S., Korslund, Kathryn E., Linehan, Marsha M.

    374 cited

12. A Pilot Prospective, Randomized, Placebo-Controlled Trial of Bilevel Positive Airway Pressure in Acute Asthmatic Attack

    2003 · CHEST Journal · Soroksky, Arie, Stav, David, Shpirer, Isaac

    340 cited

13. Aerobic exercise for Alzheimer's disease: A randomized controlled pilot trial

    2017 · PLoS ONE · Morris, Jill K., Vidoni, Eric D., Johnson, David K. et al.

    321 cited

14. Mindfulness Training Modifies Cognitive, Affective, and Physiological Mechanisms Implicated in Alcohol Dependence: Results of a Randomized Controlled Pilot Trial

    2010 · Journal of Psychoactive Drugs · Garland, Eric L., Gaylord, Susan, Boettiger, Charlotte A. et al.

    320 cited

15. Exploring the Effect of Companion Robots on Emotional Expression in Older Adults with Dementia: A Pilot Randomized Controlled Trial

    2013 · Journal of Gerontological Nursing · Moyle, Wendy, Cooke, Marie, Beattie, Elizabeth et al.

    320 cited

16. Etanercept in Sjögren's syndrome: A twelve‐week randomized, double‐blind, placebo‐controlled pilot clinical trial

    2004 · Arthritis & Rheumatism · Sankar, Vidya, Brennan, Michael T., Kok, Marc R. et al.

    303 cited

17. A Pilot Randomized Controlled Trial of Combined Trauma-Focused CBT and Sertraline for Childhood PTSD Symptoms

    2007 · Journal of the American Academy of Child & Adolescent Psychiatry · Cohen, Judith A., Mannarino, Anthony P., Perel, James M. et al.

    296 cited

18. Riluzole for relapse prevention following intravenous ketamine in treatment-resistant depression: a pilot randomized, placebo-controlled continuation trial

    2009 · The International Journal of Neuropsychopharmacology · Mathew, Sanjay J., Murrough, James W., Rot, Marije aan het et al.

    293 cited

19. Conservative versus Liberal Oxygenation Targets for Mechanically Ventilated Patients. A Pilot Multicenter Randomized Controlled Trial

    2015 · American Journal of Respiratory and Critical Care Medicine · Panwar, Rakshit, Hardie, M.J., Bellomo, Rinaldo et al.

    291 cited

20. A Randomized Controlled Pilot Trial of Modified Whole Blood versus Component Therapy in Severely Injured Patients Requiring Large Volume Transfusions

    2013 · Annals of Surgery · Cotton, Bryan A., Podbielski, Jeanette M., Camp, Elizabeth A. et al.

    288 cited

21. A Randomized Controlled Pilot Trial of Oral N-Acetylcysteine in Children with Autism

    2012 · Biological Psychiatry · Hardan, Antonio Y., Fung, Lawrence K., Libove, Robin A. et al.

    286 cited

22. A Randomized Placebo-Controlled Pilot Trial of Omega-3 Fatty Acids and Alpha Lipoic Acid in Alzheimer's Disease

    2013 · Journal of Alzheimer s Disease · Shinto, Lynne, Quinn, Joseph F., Montine, Thomas J. et al.

    283 cited

23. Low‐fat versus ketogenic diet in Parkinson's disease: A pilot randomized controlled trial

    2018 · Movement Disorders · Phillips, Matthew, Murtagh, Deborah K. J., Gilbertson, Linda J. et al.

    282 cited

24. A pilot randomized controlled trial of the Yoga of Awareness program in the management of fibromyalgia

    2010 · Pain · Carson, James W., Carson, Kimberly M., Jones, Kim Dupree et al.

    280 cited

25. A randomized, 48-week, placebo-controlled trial of intensive lifestyle modification and/or metformin therapy in overweight women with polycystic ovary syndrome: A pilot study

    2004 · Fertility and Sterility · Hoeger, Kathleen M., Kochman, Lynda, Wixom, Nellie et al.

    280 cited

26. Metformin in Amnestic Mild Cognitive Impairment: Results of a Pilot Randomized Placebo Controlled Clinical Trial

    2016 · Journal of Alzheimer s Disease · Luchsinger, José A., Perez, Thania, Chang, Helena et al.

    278 cited

27. An Open Label, Pilot, Randomized Controlled Trial of Noradrenaline<i>Versus</i>Terlipressin in the Treatment of Type 1 Hepatorenal Syndrome and Predictors of Response

    2008 · The American Journal of Gastroenterology · Sharma, Praveen, Kumar, Ashish, Shrama, Brajesh C. et al.

    277 cited

28. Safety and pharmacokinetics of pravastatin used for the prevention of preeclampsia in high-risk pregnant women: a pilot randomized controlled trial

    2015 · American Journal of Obstetrics and Gynecology · Costantine, Maged M., Cleary, Kirsten, Hébert, Mary F. et al.

    271 cited

29. Passionflower in the treatment of generalized anxiety: a pilot double-blind randomized controlled trial with oxazepam

    2001 · Journal of Clinical Pharmacy and Therapeutics · Akhondzadeh, Shahin, Naghavi, Hamid Reza, Vazirian, Mohsen et al.

    262 cited

30. A Binational Multicenter Pilot Feasibility Randomized Controlled Trial of Early Goal-Directed Mobilization in the ICU*

    2016 · Critical Care Medicine · Hodgson, Carol, Bailey, Michael, Bellomo, Rinaldo et al.

    261 cited