Most-cited papers on evaluation pharmacological properties compounds efficacy

Ranked by citation count via OpenAlex. Citations update on a rolling basis; list regenerates every 24h.

1. A Molecular Docking Approach to Evaluate the Pharmacological Properties of Natural and Synthetic Treatment Candidates for Use against Hypertension

   2019 · International Journal of Environmental Research and Public Health · Attique, Syed Awais, Hassan, Muhammad, Usman, Muhammad et al.

   178 cited

2. Evaluation Of The Pharmacological Properties Of Nutmeg Oil In Rats And Mice

   2000 · Pharmaceutical Biology · Olajide, Olumayokun A., Makinde, J. M., Awe, S. O.

   178 cited

3. Evaluation of the pharmacological properties and clinical results of the synthetic pentasaccharide (fondaparinux)

   2003 · Thrombosis Research · Samama, Meyer‐Michel, Gerotziafas, Grigoris

   159 cited

4. Characterization of Pharmacologic and Pharmacokinetic Properties of CCX168, a Potent and Selective Orally Administered Complement 5a Receptor Inhibitor, Based on Preclinical Evaluation and Randomized Phase 1 Clinical Study

   2016 · PLoS ONE · Bekker, Pirow, Dairaghi, Daniel J., Seitz, Lisa et al.

   148 cited

5. Synthesis, Structure-Activity Relationships, and Pharmacological Evaluation of Pyrrolo[3,2,1-ij]quinoline Derivatives: Potent Histamine and Platelet Activating Factor Antagonism and 5-Lipoxygenase Inhibitory Properties. Potential Therapeutic Application in Asthma

   1995 · Journal of Medicinal Chemistry · Paris, Dominique, Cottin, Michel, Demonchaux, Patrice et al.

   120 cited

6. MEDICINAL PROPERTIES IN THE DIET OF GORILLAS: AN ETHNO-PHARMACOLOGICAL EVALUATION

   2002 · Kyoto University Research Information Repository (Kyoto University) · Cousins, Don, Huffman, Michael A.

   109 cited

7. Design, synthesis and pharmacological evaluation of hybrid molecules out of quinazolinimines and lipoic acid lead to highly potent and selective butyrylcholinesterase inhibitors with antioxidant properties

   2008 · Bioorganic & Medicinal Chemistry · Decker, Michael, Kraus, Birgit, Heilmann, Jörg

   94 cited

8. Homomeric beta 1 gamma-aminobutyric acid A receptor-ion channels: evaluation of pharmacological and physiological properties.

   1996 · Molecular Pharmacology · Krishek, Belinda J., Moss, Stephen J., Smart, Trevor G.

   90 cited

9. Synthesis and pharmacological evaluation of amide conjugates of NSAIDs with L-cysteine ethyl ester, combining potent antiinflammatory and antioxidant properties with significantly reduced gastrointestinal toxicity

   2004 · Bioorganic & Medicinal Chemistry Letters · Galanakis, Dimitrios, Kourounakis, Angeliki P., Tsiakitzis, Karyophyllis C. et al.

   77 cited

10. Pharmacological evaluation of N-allynormetazocine (SKF 10,047) on the basis of its discriminative stimulus properties in the rat.

    1983 · Journal of Pharmacology and Experimental Therapeutics · Shannon, H E

    73 cited

11. Physicochemical and Pharmacological Properties of Palm Oil: an Approach for Quality, Safety, and Nutrition Evaluation of Palm Oil

    2022 · Food Analytical Methods · Edo, Great Iruoghene, Makinde, Mamoke Glory, Nwosu, Laurine Chikodiri et al.

    71 cited

12. Clozapine (Leponex) compared with chlorpromazine: a double-blind evaluation of pharmacological and clinical properties.

    1974 · PubMed · Ekblom, Bengt, Je, Häggström

    70 cited

13. Plant composition, pharmacological properties and mutagenic evaluation of a commercial Zulu herbal mixture: Imbiza ephuzwato

    2010 · Journal of Ethnopharmacology · Ndhlala, A.R., Finnie, J.F., Staden, J. Van

    67 cited

14. Pharmacological evaluation of aqueous extract of syzigium cumini for its antihyperglycemic and antidyslipidemic properties in diabetic rats fed a high cholesterol diet—Role of PPARγ and PPARα

    2017 · Biomedicine & Pharmacotherapy · Sharma, Sandhya, Pathak, Sachchidanand, Gupta, Gaurav et al.

    67 cited

15. Re-evaluation of lisuride pharmacology: 5-hydroxytryptamine 1A receptor-mediated behavioral effects overlap its other properties in rats

    2002 · Psychopharmacology · Marona‐Lewicka, Danuta, Kurrasch‐Orbaugh, Deborah, Selken, Jennifer et al.

    61 cited

16. Synthesis and pharmacological evaluation of 2(3H)-furanones and 2(3H)-pyrrolones, combining analgesic and anti-inflammatory properties with reduced gastrointestinal toxicity and lipid peroxidation

    2008 · European Journal of Medicinal Chemistry · Alam, Mohammad Mumtaz, Husain, Asif, Hasan, S. S. et al.

    51 cited

17. Synthesis and Evaluation of Pharmacological Properties of Novel Annelated 2,3-Benzodiazepine Derivatives

    2003 · Journal of Medicinal Chemistry · Gitto, Rosaria, Orlando, Valérie, Quartarone, Silvana et al.

    50 cited

18. Nifekalant and Disopyramide in a Patient with Short QT Syndrome: Evaluation of Pharmacological Effects and Electrophysiological Properties

    2008 · Pacing and Clinical Electrophysiology · Mizobuchi, Masahiro, Enjoji, Yoshihisa, Yamamoto, Ryûji et al.

    43 cited

19. Synthesis and Evaluation of Pharmacological and Pharmacokinetic Properties of 11<i>H</i>-[1,2,4]Triazolo[4,5-<i>c</i>][2,3]benzodiazepin-3(2<i>H</i>)-ones

    2000 · Journal of Medicinal Chemistry · Zappalà, Maria, Gitto, Rosaria, Bevacqua, Francesca et al.

    42 cited

20. Synthesis and pharmacological evaluation of some new tetrahydroisoquinoline derivatives inhibiting dopamine uptake and/or possessing a dopaminomimetic property

    1986 · Journal of Medicinal Chemistry · ZARA‐KACZIAN, E., György, L, DEÁK, G. et al.

    41 cited

21. Synthesis and preliminary evaluation of pharmacological properties of some piperazine derivatives of xanthone

    2012 · Bioorganic & Medicinal Chemistry · Szkaradek, Natalia, Rapacz, Anna, Pytka, Karolina et al.

    41 cited

22. Preliminary evaluation of pharmacological properties of some xanthone derivatives

    2008 · Bioorganic & Medicinal Chemistry · Marona, Henryk, Szkaradek, Natalia, Rapacz, Anna et al.

    40 cited

23. Design, Synthesis, and Evaluation of Pharmacological Properties of Cinnamic Derivatives as Antiatherogenic Agents

    2005 · Journal of Medicinal Chemistry · Lapeyre, Caroline, Delomenède, Mélanie, Bedos‐Belval, Florence et al.

    39 cited

24. Synthesis and evaluation of pharmacological properties of some new xanthone derivatives with piperazine moiety

    2013 · Bioorganic & Medicinal Chemistry Letters · Waszkielewicz, Anna M., Gunia, A., Szkaradek, Natalia et al.

    37 cited

25. Synthesis and Preliminary Pharmacological Evaluation of Aryl Dithiolethiones with Cyclooxygenase-2-Selective Inhibitory Activity and Hydrogen Sulfide-Releasing Properties

    2010 · Australian Journal of Chemistry · Zanatta, Shannon D., Jarrott, Bevyn, Williams, Spencer J.

    36 cited

26. A Multi-Biochemical and In Silico Study on Anti-Enzymatic Actions of Pyroglutamic Acid against PDE-5, ACE, and Urease Using Various Analytical Techniques: Unexplored Pharmacological Properties and Cytotoxicity Evaluation

    2019 · Biomolecules · Šudomová, Miroslava, Hassan, Sherif T. S., Khan, Haroon et al.

    36 cited

27. PEG-Modified Protamine with Improved Pharmacological/Pharmaceutical Properties as a Potential Protamine Substitute:  Synthesis and in Vitro Evaluation

    2004 · Bioconjugate Chemistry · Chang, Li-Chien, Lee, Hsiao-Feng, Chung, Meng-Ju et al.

    35 cited

28. Design, synthesis and evaluation of novel 16-imidazolyl substituted steroidal derivatives possessing potent diversified pharmacological properties

    2012 · Steroids · Bansal, Ranju, Guleria, Sheetal, Thota, Sridhar et al.

    35 cited

29. Evaluation of Pelargonium extract and oil as eco-friendly corrosion inhibitor for steel in acidic chloride solutions and pharmacological properties

    2014 · Research on Chemical Intermediates · Ouadi, Y. El, Bouyanzer, A., Majidi, L. et al.

    35 cited

30. Rhamnus alaternus Plant: Extraction of Bioactive Fractions and Evaluation of Their Pharmacological and Phytochemical Properties

    2021 · Antioxidants · Nekkaa, Amine, Benaissa, Akila, Mutelet, Fabrice et al.

    33 cited