Most-cited papers on treatment protocols patients prioritize preventive

Ranked by citation count via OpenAlex. Citations update on a rolling basis; list regenerates every 24h.

1. Skin Toxicity Evaluation Protocol With Panitumumab (STEPP), a Phase II, Open-Label, Randomized Trial Evaluating the Impact of a Pre-Emptive Skin Treatment Regimen on Skin Toxicities and Quality of Life in Patients With Metastatic Colorectal Cancer

   2010 · Journal of Clinical Oncology · Lacouture, Mario E., Mitchell, Edith P., Piperdi, Bilal et al.

   470 cited

2. Selective bladder preservation by combined modality protocol treatment: long-term outcomes of 190 patients with invasive bladder cancer

   2002 · Urology · Shipley, William U., Kaufman, Donald S., Zehr, Elizabeth M et al.

   325 cited

3. A randomized study comparing cisplatin or carboplatin with etoposide in patients with advanced non-small-cell lung cancer: European Organization for Research and Treatment of Cancer Protocol 07861.

   1990 · Journal of Clinical Oncology · Klášterský, Jean, Sculier, Jean‐Paul, Lacroix, H. et al.

   246 cited

4. A randomized phase iii protocol for the evaluation of misonidazole combined with radiation in the treatment of patients with brain metastases (RTOG-7916)

   1991 · International Journal of Radiation Oncology*Biology*Physics · Komarnicky, Lydia, Phillips, Theodore L., Martz, Karen et al.

   237 cited

5. Electroencephalographic and perceptual asymmetry differences between responders and nonresponders to an SSRI antidepressant21Data from two treatment protocols were combined so as to yield sufficient samples of female and male fluoxetine responders and nonresponders. With the exception of the initial placebo period in one study, the treatment protocols were comparable in terms of both fluoxetine doses and the raters evaluating treatment response. Most importantly, the differences between fluoxetine responders and nonresponders reported for the total samples were also evident when only the data for the placebo-controlled protocol were analyzed; however, the larger total sample allowed us to also take patient gender into account.22The 18 healthy women were screened for psychopathology using a structured interview schedule and were excluded if they had a hearing loss, substance abuse, a history of head trauma, or other neurologic disorder. They did not differ significantly from the female patients in education (mean = 15.8, SD = 1.3) or handedness (LQ = 84.7, SD = 20.6), but they were somewhat younger than the female patients [mean age = 27.6, SD = 6.9;t(35) = 3.21,p = .001]. Age was not, however, related to perceptual asymmetry scores of either female patients (r = −.01, ns) or male patients (r = −.02, ns) on the fused words test. Nor was age significantly correlated with alpha asymmetry scores of female patients (r = −.09, ns) or male patients (r = .11, ns).

   2001 · Biological Psychiatry · Bruder, Gerard E., Stewart, Jonathan W., Tenke, Craig E. et al.

   224 cited

6. Rehabilitation treatment of gait in patients with Parkinson's disease with freezing: A comparison between two physical therapy protocols using visual and auditory cues with or without treadmill training

   2009 · Movement Disorders · Frazzitta, Giuseppe, Maestri, Roberto, Uccellini, Davide et al.

   224 cited

7. Early rehabilitation in post-acute COVID-19 patients: data from an Italian COVID-19 Rehabilitation Unit and proposal of a treatment protocol

   2020 · European Journal of Physical and Rehabilitation Medicine · Curci, Claudio, Pisano, Fabrizio, Bonacci, Eleonora et al.

   218 cited

8. Good Outcome Associated with a Standardized Treatment Protocol Using Selective Postoperative Radiation in Patients with Clinical Stage I Adenocarcinoma of the Endometrium

   1995 · Gynecologic Oncology · Carey, Mark, OʼConnell, G., Johanson, Curtis R. et al.

   163 cited

9. Site of disease and treatment protocol as correlates of swallowing function in patients with head and neck cancer treated with chemoradiation

   2005 · Head & Neck · Logemann, Jeri A., Rademaker, Alfred, Pauloski, Barbara Roa et al.

   163 cited

10. Treatment of hairy cell leukemia with 2-chlorodeoxyadenosine via the Group C protocol mechanism of the National Cancer Institute: a report of 979 patients.

    1998 · Journal of Clinical Oncology · Cheson, Bruce D., Sorensen, John M., Vena, D. et al.

    156 cited

11. The influence of tumor- and treatment-related factors on the development of local recurrence in osteosarcoma after adequate surgery. An analysis of 1355 patients treated on neoadjuvant Cooperative Osteosarcoma Study Group protocols

    2010 · Annals of Oncology · Andreou, Dimosthenis, Bielack, Stefan, Carrle, D. et al.

    152 cited

12. Anemia in patients with cancer: Incidence, causes, impact, management, and use of treatment guidelines and protocols

    2007 · American Journal of Health-System Pharmacy · Schwartz, Rowena

    138 cited

13. BFM-oriented treatment for children with acute lymphoblastic leukemia without cranial irradiation and treatment reduction for standard risk patients: results of DCLSG protocol ALL-8 (1991–1996)

    2002 · Leukemia · Kamps, WA, Bökkerink, J.P.M., Hakvoort-Cammel, FGAJ et al.

    136 cited

14. Treatment of glioma patients with ketogenic diets: report of two cases treated with an IRB-approved energy-restricted ketogenic diet protocol and review of the literature

    2015 · Cancer & Metabolism · Schwartz, Kenneth A., Chang, Howard T., Nikolai, Michele et al.

    136 cited

15. Evaluation of a standardized treatment regimen of anti-tuberculosis drugs for patients with multi-drug-resistant tuberculosis (STREAM): study protocol for a randomized controlled trial

    2014 · Trials · Nunn, Andrew, Rusen, I. D., Deun, Armand Van et al.

    130 cited

16. Conventional and advanced implant treatment in the type II diabetic patient: surgical protocol and long-term clinical results.

    2008 · PubMed · Tawil, Georges, Younan, Roland, Azar, Pierre et al.

    129 cited

17. Dysfunctional patients with temporomandibular disorders: Evaluating the efficacy of a tailored treatment protocol.

    1996 · Journal of Consulting and Clinical Psychology · Turk, Dennis C., Rudy, Thomas E., Kubinski, John A. et al.

    129 cited

18. International phase I study protocol to develop a patient-reported outcome measure for adolescents and adults receiving gender-affirming treatments (the GENDER-Q)

    2018 · BMJ Open · Klassen, Anne F., Kaur, Manraj, Johnson, Natasha et al.

    128 cited

19. Do treatment protocols improve end results? A study of survival of patients with multiple myeloma in Finland.

    1989 · BMJ · Karjalainen, Sakari, Palva, I. P.

    127 cited

20. Multimodal Treatment of Malignant Sacrococcygeal Germ Cell Tumors: A Prospective Analysis of 66 Patients of the German Cooperative Protocols MAKEI 83/86 and 89

    2001 · Journal of Clinical Oncology · Göbel, U., Schneider, Dominik T., Calaminus, Gabriele et al.

    125 cited

21. Masticatory function in patients with an extremely resorbed mandible restored with mandibular implant‐retained overdentures: comparison of three types of treatment protocols

    2005 · Journal of Oral Rehabilitation · Stellingsma, Kees, Slagter, A.P., STEGENGA, B. et al.

    123 cited

22. Outcome of Patients with Complete Unilateral Cleft Lip and Palate: 20-Year Follow-Up of a Treatment Protocol

    2018 · Plastic & Reconstructive Surgery · Pai, Betty C. J., Hung, Yi-Tan, Wang, Ruby S. H. et al.

    123 cited

23. Adult T-cell acute lymphoblastic leukemia: biologic profile at presentation and correlation with response to induction treatment in patients enrolled in the GIMEMA LAL 0496 protocol

    2005 · Blood · Vitale, Alessandro

    123 cited

24. Outcome of patients with acute promyelocytic leukemia failing to front-line treatment with all-trans retinoic acid and anthracycline-based chemotherapy (PETHEMA protocols LPA96 and LPA99): benefit of an early intervention

    2007 · Leukemia · Esteve, Jordi, Escoda, Lourdes, Martı́n, Guillermo et al.

    120 cited

25. Growth hormone co-treatment within a GnRH agonist long protocol in patients with poor ovarian response: a prospective, randomized, clinical trial

    2008 · Journal of Assisted Reproduction and Genetics · Küçük, Tansu, Kozinoglu, Hakan, Kaba, Ayten

    116 cited

26. Can CT scan protocols used for radiotherapy treatment planning be adjusted to optimize image quality and patient dose? A systematic review

    2017 · British Journal of Radiology · Davis, Anne, Palmer, Antony L., Nisbet, A.

    113 cited

27. Actionable Tumor Alterations and Treatment Protocol Enrollment of Pediatric and Young Adult Patients With Refractory Cancers in the National Cancer Institute–Children's Oncology Group Pediatric MATCH Trial

    2022 · Journal of Clinical Oncology · Parsons, D. Williams, Janeway, Katherine A., Patton, David R. et al.

    111 cited

28. Multicentric parallel phase II trial of the polo-like kinase 1 inhibitor BI 2536 in patients with advanced head and neck cancer, breast cancer, ovarian cancer, soft tissue sarcoma and melanoma. The first protocol of the European Organization for Research and Treatment of Cancer (EORTC) Network Of Core Institutes (NOCI)

    2010 · European Journal of Cancer · Schöffski, Patrick, Blay, Jean‐Yves, Grève, Jacques De et al.

    109 cited

29. Thromboembolism in acute lymphoblastic leukemia: results of NOPHO ALL2008 protocol treatment in patients aged 1 to 45 years

    2018 · Blood · Rank, Cecilie Utke, Toft, Nina, Tuckuviene, Ruta et al.

    107 cited