Recent papers on Developmental Stage Specificity

Sorted by publication year (newest first) via OpenAlex. List regenerates every 24h.

  1. Developmental stage-specific disruption of iron allocation by a ZmYSL2 mutation in maize

    2026 · Planta · Wang, Yikai, Zhang, Ke, An, Chuang et al.

    2026
  2. Modelling developmental stage-specific climate effects and extremes on wheat yield under global change

    2026 · Milek, Joel Joshua, Koppensteiner, Lukas J., Bernardini, Luca Giuliano et al.

    2026
  3. Developmental stage-specific responses to extreme climatic events and environmental variability in great tit nestlings

    2025 · bioRxiv (Cold Spring Harbor Laboratory) · Satarkar, Devi, López‐Idiáquez, David, Sepil, Irem et al.

    2025
  4. Developmental stage-specific expression of the phytase1 gene and its association with phytase activity in maize kernel

    2026 · Molecular Biology Reports · Ganesh, Botta Thandava, Katral, Ashvinkumar, Muthusamy, Vignesh et al.

    2026
  5. Protein kinase N2 (PKN2) is essential for embryonic heart development, but the precise timing and cellular requirement in cardiomyocytes are not well understood. In a constitutive cardiomyocyte specific knockout (cKO) of PKN2, we observed partially penetrant early postnatal lethality, nonprogressive systolic dysfunction in survivors, and a distinctive coin pouch ventricular geometry resembling the embryonic shape, linking the phenotype to a developmental origin rather than ongoing pathology. By tracking heart morphogenesis, we found that mutant and control hearts were still grossly indistinguishable at E10.5, defining an unbiased stage for molecular profiling before secondary remodeling. Integrative RNAseq, proteomics, and phosphoproteomics at E10.5 revealed concurrent induction of actin cytoskeleton and motility programs and repression of chromosome condensation and mitotic modules in PKN2 cKO hearts. These molecular changes coincided with reduced cardiomyocyte proliferation at E10.5 E11.5 and early divergence in ventricular shape trajectories. Inducible cardiomyocyte specific PKN2 knockout hearts analyzed by quantitative light-sheet microscopy based morphometrics pinpointed the critical dependence window: recombination induced at E7.5 reproduced the ventricular geometry characteristic of constitutive PKN2 cKO hearts, whereas induction at E10.5 spared gross morphology. Together, these data show that cardiomyocytes depend on PKN2 during an early proliferative and migratory phase that drives ventricular wall formation, after which PKN2 becomes dispensable for heart morphogenesis. This temporally restricted requirement reconciles previous observations of PKN2s essential role in mesodermal and epithelial morphogenesis, suggesting a shared function in coordinating cytoskeletal remodeling with tissue expansion during organogenesis.

    2026 · Open MIND · Chen, Ju

    2026
  6. Exploring the increasing aneuploidy stress effects on embryo morphokinetic development: non-linear and stage-specific disruption in developmental timing

    2025 · Journal of Assisted Reproduction and Genetics · Roman, Iulian, Coull, Graham D., Michielsen, Adriana J. et al.

    2025
  7. 2025
  8. Specificity and Time-dependent Toxicity of Some Acaricides Against the Developmental Stages of the Two-Spotted Spider Mite, Tetranychus urticae Koch (Acari: Tetranychidae)

    2025 · Journal of the Advances in Agricultural Researches/Journal of the Advances in Agricultural Researches · Massoud, Magdy A., Mesbah, H. A., Bakr, Anar et al.

    2025
  9. Metabolites detected at specific developmental stages.

    2025 · Figshare · (130663), Martin Sládek, (634836), Pavel Houdek, (18859002), Tomáš Čajka et al.

    2025
  10. 2025
  11. The KASH protein UNC-83 differentially regulates kinesin-1 activity to control developmental stage-specific nuclear migration

    2025 · Current Biology · Gümüşderelioğlu, Selin, Sahabandu, Natalie, Elnatan, Daniel et al.

    2025
  12. Developmental stage–specific expression and localization of p57Kip2 in the mouse placenta

    2025 · Placenta · Tabuse, Mari, Nakamura, Hitomi, Tanaka, Yoshitomo et al.

    2025

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