Recent papers on Research Design and Measurement

Sorted by publication year (newest first) via OpenAlex. List regenerates every 24h.

Optical Design and Efficiency Measurement of an Extreme Ultraviolet High-Resolution Spectrometer for Unresolved Transition Array Research
2026 · Institutional Repositories DataBase (IRDB) · Tomoko, Kawate, Kawate, Tomoko, Sakaue, H. A. et al.
2026
Design and Performance Research of a Spindle-Integrated Rotational Piezoelectric Testing System for Upset Force Measurement During Welding Processes
2026 · IEEE Sensors Journal · Yuan, Mingyu, Mai, Shilu, Liu, Jinlong et al.
2026
Research and design of a calibration and verification system for tape measures and rulers with a measurement range of up to 30 metres
2026 · Ministry of Science and Technology Vietnam
2026
Increasing Trends of Minimal Residual Disease Measurement in Trials Focusing on Multiple Myeloma Treatment: A Systematic Analysis of Clinical Research Design From 2014 to 2025
2026 · European Journal Of Haematology · Choon‐Quinones, Mimi, Obeng, George Dennis, Asiedu‐Ayeh, Benjamin et al.
2026
WORKING PAPER • RESEARCH SERIES -PART 2 Municipal Waste Systems Under Policy Pressure: Mandates, Measurement Constraints, and System Design in U.S. Waste Infrastructure
2026 · SSRN Electronic Journal · Anderson, Cam
2026
Thermal proteome profiling (TPP) and its higher-throughput derivative, the proteome integral solubility alteration (PISA) assay, measure changes in protein thermal stability upon ligand binding or other perturbations and have been widely adopted in drug discovery and biomedical research. Though the PISA workflow is straightforward, key parameters, including detergent concentration, methods for removing denatured aggregates, and temperature range selection, vary across studies and can markedly influence assay outcomes. Yet these factors have not been systematically evaluated, limiting rational experimental design and data interpretation. Here, through a combined use of TPP, PISA, tandem mass tag (TMT)-based multiplexing, and computational simulation, we systematically characterize these parameters based on the melting behavior of ~9,000 proteins. We find that reducing detergent concentration elevates apparent Tm by 1.5-2oC proteome-wide, and aggregate removal by filtration versus centrifugation further alters measurements. We leverage these observations to optimize PISA then apply the optimized conditions to identify the aminopeptidase NPEPPS as a previously uncharacterized binding partner of angiotensin II, a key vasoactive peptide hormone in blood pressure regulation. Together, this work provides a general framework for PISA assay design and data interpretation, and further extends the utility of PISA beyond small molecules to dissecting peptide-protein interactions, an increasingly important modality in drug discovery.
2026 · Open MIND · Yu, Qing
2026
Research on the Design of Object Measurement Device Based on Monocular Vision
2025 · Yu, Yan, Wu, Peixiong
2025
Research on the Energy Storage Measurement and Control System for Distribution Transformer Areas Based on the Distribution Internet of Things and Its Cloud-Edge Collaborative Optimization Design
2025 · Xu, Jiayi, Zhou, Shengjie, Tan, Tao et al.
2025
Measurement and Design Heterogeneity in Perceived Message Effectiveness Studies: A Call for Research
2025 · UNC Libraries · Yzer, Marco, Noar, Seth M., Barker, Joshua
2025
Research on the Design and Fabrication of a Fuel Consumption Measurement Device for Cars
2025 · Tao, Ngo Quang, Nguyen, Quang Thanh
2025
Research on the Design of an Automatic Measurement System for Non-standard Device Dimensions Based on Computer Vision
2025 · Educational Innovation Research · Chen, Jicheng, Wang, Dawei
2025
User Experience Measurement in Design-Based Research on Online Educational Platforms: Contextualization of Real-World Environments Within Sustainable Development Goals for Computational Thinking
2025 · Journal of Advanced Academics · Tariq, Rasikh, Ramírez-Montoya, M.S., Awotwe, Tabbi Wilberforce et al.
2025
Design of a New Energy Battery Explosion Warning System Based on Spectral Detection and Research on Optoelectronic Measurement Methods
2025 · Zheng, Yi, Zhang, Xu, Chen, Wanyang
2025
Design and research of a domestic measurement and control system of microcomputer for hydroelectric units
2025 · IET conference proceedings. · Qi, Lili, Xiao, Cong, Si, Yong et al.
2025
Modular Design of an Extendable DC-PD Measurement System for Research and Monitoring Applications
2025 · Valtin, Markus, Brose, Christian, Plath, Ronald
2025
Research on the functional design of a virtual power plant terminal measurement and control device suitable for real-time spot market
2025 · Journal of Physics Conference Series · Bao, Yueyue, Zhang, Yi, Zhang, Feng et al.
2025
(In)validity by Design? Separating Measurement Validation from Substantive Research in HCI
2025 · Borgert, Nele, Jansen, Luisa, Elson, Malte
2025
Research on In-situ Stress Measurement and Roadway Support Design in Coal Seam
2025 · Frontiers in Sustainable Development · Zhao, Jiyu
2025
Design of MWPC-based muography measurements for geophysical research
2025 · Stefán, Boglárka Abigél, Balázs, László, Hamar, G. et al.
2025
Research on a novel intelligent bearing system with three-parameter measurement: integration structure design and state monitoring capability analysis
2025 · Structural Health Monitoring · Shi, Huaitao, Song, Zhenting, Ye, Xin et al.
2025
From Exploration to Measurement: A Research Design on Mental Health Constructs Based on Sundanese Culture “Tri Tangtu” among Elementary School Students
2025 · Advances in Social Science, Education and Humanities Research/Advances in social science, education and humanities research · Riyadi, Arie Rakhmat, Somantri, Mubarok, Maulidah, Neni et al.
2025
Design and Research of Pvdf Piezoelectric Film Three-Dimensional Force Sensor for Dynamic Load Measurement
2025 · SSRN Electronic Journal · Yan, Kaiqiang, Wu, W.X., Cheng, Yunping et al.
2025
Design-Based Research on Engineering Graduate Course Reform and Practice—A Case Study of Developing a Research-Based Teaching Model for “Radiation Measurement and Instruments”
2025 · Advances in Education · 夏, 文明
2025
Research on the Design and Implementation of Multi-Sensors Inertial Measurement Unit Health Management System
2025 · Zhang, Wenrui
2025
Research and Design of a System for the Measurement of Dielectric Characteristics of Near-Bit Fluids
2025 · Mechanisms and machine science · Wang, Zizhen, Li, Jun, Yang, Hongwei et al.
2025
Design and algorithm research of high-precision laser speed measurement system
2024 · Liang, Yuepeng, Liao, Tongqing, Hu, Runfeng
2024
Experimental researches on temperature measurement of inclinometer based on mixed level uniform design
2024 · Zhang, Hongyue, Jiang, Dinan, Jiang, Tianjie et al.
2024
Design and Research of Terminal Image Measurement System Based on Human-Computer Interaction and Object Detection
2024 · Guo, Fang, Guo, Jun, Jiang, Fuzhen et al.
2024

Recent papers on Research Design and Measurement

Command palette