Recent papers on clinical translation patients therapeutic interventions

Sorted by publication year (newest first) via OpenAlex. List regenerates every 24h.

1. IS PAT READY FOR CLINICAL TRANSLATION? A SMART BIOPROCESSING PROOF-OF-CONCEPT USING PATIENT-DERIVED MATERIAL

   2026 · Cytotherapy · Statham, P., Pararasa, C., Filipiak, M. et al.

   2026

2. Abstract SY36-02: Human cancer models: From patient-derived systems to clinical translation

   2026 · Cancer Research · Habowski, Amber N., Kouassi, Fatim, Patel, Hardik et al.

   2026

3. Clinical guidance and practical recommendations for probiotic use in patients with irritable bowel syndrome, functional constipation, and <i>Clostridioides difficile</i> infection considering sex-based differences: a Korean translation

   2026 · The Ewha Medical Journal · Kim, Yong Woon, Park, Seon‐Young, Kang, Seung Joo et al.

   2026

4. Clinical Potential of Artificial Bone Scintigraphy from Early-Phase Bone Scintigraphy Using Unpaired Image-to-Image Translation in Patients with Breast Cancer: A Single-Center Prospective Study

   2026 · Tomography · Park, Yong-Jin, Kim, Il-Hyun, An, Young‐Sil et al.

   2026

5. Patient-Specific Disease Modeling with hiPSCs: From Mechanisms to Clinical Translation

   2026 · Zenodo (CERN European Organization for Nuclear Research) · science, regenerative medicine

   2026

6. Translating clinical evidence into real-world experience with the Slim Modiolar electrode (CI632) in China: patient and surgeon perspectives on hearing performance and satisfaction

   2026 · Frontiers in Audiology and Otology · Tian, Xiguang, Cui, Jingwe, Zeng, Shunnian et al.

   2026

7. Automating mHealth Development: A Prompt Engineering Approach to Translate Clinical Patient Descriptions into Nursing Basic Components

   2026 · Zenodo (CERN European Organization for Nuclear Research) · Anonymous, Anonymous, Anonymous

   2026

8. P1008 Translating tumor biology into clinical practice using patient-derived organoids in renal cell carcinoma

   2026 · European Urology · Shahini, A., Mehrjoo, Z., Kuasne, H. et al.

   2026

9. Additional file 1 of An expert opinion on the management of pediatric patients with wheezing and mild asthma: translating 2025 GINA strategy report into clinical practice in Italy

   2026 · Open MIND · Santamaria, Francesca, Baraldi, Eugenio, Cavalieri, Luca et al.

   2026

10. An expert opinion on the management of pediatric patients with wheezing and mild asthma: translating 2025 GINA strategy report into clinical practice in Italy

    2026 · ˜The œItalian Journal of Pediatrics/Italian journal of pediatrics · Santamaria, Francesca, Baraldi, Eugenio, Cavalieri, Luca et al.

    2026

11. Use of knowledge translation frameworks to implement diagnosis of upper quadrant lymphedema clinical practice guideline to improve patient care

    2026 · Disability and Rehabilitation · Wampler, Meredith, Campione, Elizabeth, Newell, Alaina et al.

    2026

12. A clinically translatable pathomics-based predictive model for preoperative prognostic assessment in patients with endometrial cancer

    2026 · Discover Oncology · Liu, Jing, Zhao, Hongyan, Zhang, X et al.

    2026

13. Translating Clinical Evidence into Practice: Improving Patient Outcomes with Triplet Therapy in mHSPC – Module 3: Managing Cardiovascular Risk During mHSPC Treatment

    2026 · Open MIND · Mustafa, Nasir

    2026

14. Metastatic castration-resistant prostate cancer (mCRPC) remains lethal as adaptive resistance to standard of care therapy develops, often driven by AR splice variants alongside transcriptional and translational reprogramming. To identify strategies capable of overcoming these mechanisms, we performed an unbiased high-throughput screen of 2,480 mechanistically annotated compounds across advanced prostate cancer models. Exportin-1 (XPO1)-mediated nuclear export emerged as a critical dependency, and matrix-based combination screening uncovered robust synergy between inhibitors of XPO1 and the translation initiation factor EIF4A1. Dual inhibition induced coordinated disruption of oncogenic protein networks, including AR/AR-V7 and MYC, triggering rapid apoptosis and suppressing cell-cycle and metabolic programs. These effects extended to genetically diverse patient-derived organoids and in vivo xenografts at doses well below established tolerability limits. Together, these findings reveal concurrent control of nuclear export and protein translation as a therapeutic vulnerability in mCRPC, providing a strong rationale for clinical evaluation of XPO1-EIF4A1 co-inhibition to overcome AR-driven resistance.

    2026 · Open MIND · Figg, William D

    2026

15. A patient‐centred approach to translate remote cognitive assessments into clinical practice

    2025 · Alzheimer s & Dementia · Blane, Jasmine, Forster, Shona, Lucas, Anna et al.

    2025

16. Translating FRESCO clinical trial evidence into practice: fruquintinib as post-standard third-line therapy followed by trifluridine/tipiracil in a patient with mCRC without targetable mutations.

    2025 · PubMed · Biachi, Tiago, Shostak, Jessica

    2025

17. TRANSPIRE-DRP: a deep learning framework for translating patient-derived xenograft drug response to clinical patients via domain adaptation

    2025 · Journal of Translational Medicine · Yang, Jianye, Wu, Tian, Xue, Feiyang et al.

    2025

18. A study on Clinical Validity and Reliability of the Bengali Language Translated Gastroesophageal Reflux Disease Quality of Life Questionnaire (GERD-QOL) in Gastroesophageal Reflux Disease Patients

    2025 · Asian Journal of Medicine and Health · Bhaduri, Rupali, Pal, Arindam, Roy, Anjan et al.

    2025

19. Bimekizumab clinical efficacy responses translate into improvements in patient outcomes to Week 48 in patients with moderate to severe hidradenitis suppurativa: Results from BE HEARD I&II

    2025 · SKIN The Journal of Cutaneous Medicine · Kimball, Alexa B., Garg, Amit, Lev‐Tov, Hadar et al.

    2025

20. Clinical translation of single cell measurable residual disease (scMRD) assay in real world Acute Myeloid Leukemia (AML) patients

    2025 · Blood · Micin, Katarina, Madarang, Ellen, Nong, Tiffany et al.

    2025