exposure tissues microplastics metabolic disease

The gap

Supporting evidence — 4 representative gaps

• Immunohistological detection of pentosidine in the epiglottis:A contribution to molecular age estimation (2026) · doi

  The relationship between pentosidine accumulation and chronological age has been established in various tissues, but the influence of confounding factors (metabolic disease, UV exposure, mechanical stress) on age estimation accuracy needs further investigation.

  Keywords: relationship pentosidine accumulation chronological established various tissues influence confounding factors metabolic disease exposure mechanical stress
• Computational Toxicology of Environmental Microplastics: In-Silico Prediction of Emerging Hepatotoxic Risks through Molecular Docking and ADMET Profiling (2026) · doi

  Long-term exposure to low concentrations of chemicals linked to microplastics may cause cumulative hepatic burden, but this requires experimental validation beyond in-silico projections of biological half-lives, biliary excretion dominance, and enzyme saturation concerns.

  Keywords: long term exposure concentrations chemicals linked microplastics cause cumulative hepatic burden requires experimental validation beyond
• Assessment of Metal Contents and Phytoremediation Potentials of Legume Species Growing around Iron Mine (2026) · doi

  The paper recommends careful livestock grazing due to high Fe and Cr levels in plant tissues but does not provide specific guidance on safe exposure thresholds, remedial management strategies, or risk assessment protocols for agricultural use of contaminated areas.

  Keywords: recommends careful livestock grazing high levels plant tissues provide specific guidance safe exposure thresholds remedial
• Potential risk assessment of different sizes of microplastics on the digestive system of hybrid sturgeon (2026) · doi

  Long-term effects and bioaccumulation of microplastics in sturgeon tissues over extended exposure periods were not addressed.

  Keywords: long term effects bioaccumulation microplastics sturgeon tissues extended exposure periods addressed