medicine5 papersavg year 2026quality 4/5moderate evidence

Retrospective Bias

Research gap analysis derived from 5 medicine papers in our local library.

The gap

Most studies rely on retrospective data collection methods, which may introduce selection and recall biases. Future research should focus on prospective validation.

Consensus across the literature

The papers collectively establish the presence of bias in retrospective studies but leave open the specific mechanisms and impacts of these biases.

Research trend

Emerging — attention growing, methods still coalescing.

Supporting evidence — 5 representative gaps

  • Case Report: Hypereosinophilic syndrome misdiagnosed as atopic dermatitis due to refractory pruritic rash masking peripheral neuropathy (2026) · doi

    Structured neurological outcome measures were not prospectively applied, and pruritus severity was retrospectively quantified, which may introduce recall bias.

    Keywords: structured neurological outcome measures prospectively applied pruritus severity retrospectively quantified introduce recall bias
  • A deep learning model based on multiphase DCE-MRI for preoperative prediction of Ki-67 expression in breast cancer (2026) · doi

    The study was conducted retrospectively at a single institution. The use of historical data may introduce selection bias, and future efforts should involve prospective, multi-center validation.

    Keywords: conducted retrospectively single institution historical introduce selection bias future efforts involve prospective multi center validation
  • AI-assisted 3D preoperative planning in primary total hip arthroplasty for secondary hip osteoarthritis: etiology-specific perioperative burden and early recovery in DDH versus post-septic sequelae (2026) · doi

    The long inclusion period may introduce temporal bias, and no formal early-versus-late comparison was performed to quantify potential learning-curve effects.

    Keywords: long inclusion period introduce temporal bias formal early versus late comparison performed quantify potential learning
  • Global insights into pediatric ischemic stroke: a bibliometric and visualization analysis (2026) · doi

    The bibliometric analysis relied on software-based algorithms, which may introduce certain biases in clustering and visualization.

    Keywords: bibliometric relied software based algorithms introduce certain biases clustering visualization
  • Comparative evaluation of bipolar versus monopolar energy platforms in G-POEM for gastroparesis: technical performance, learning curves, and clinical outcomes (2026) · doi

    This was a retrospective, single-center study, which may limit the generalizability of findings and introduce potential selection bias.

    Keywords: retrospective single center limit generalizability introduce potential selection bias

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