Limited information on the quality assessment of included studies and potential risk of bias across the reviewed studies.

The gap

Consensus across the literature

Supporting evidence — 4 representative gaps

• Effects of noninvasive brain stimulation in the treatment of poststroke depression: an overview of systematic reviews (2026) · doi

  85% of the studies were of low or critically low methodological quality, with common issues including studies not being registered, failure to explain study designs included in the review, incomplete literature searches, and lack of reporting on conflicts of interest and funding sources.

  Keywords: critically methodological quality common issues including registered failure explain designs included review incomplete literature searches
• Risk factors for scabies in school children: a systematic review (2022) · doi

  Limited information on the quality assessment of included studies and potential risk of bias across the reviewed studies.

  Keywords: limited information quality assessment included potential risk bias across reviewed
• Mechanical and oral antibiotics bowel preparation reduce the risk of surgical site infections and anastomotic leakage in colorectal surgery: a GRADE-based meta-analysis and trial sequential analysis (2026) · doi

  The lack of blinding in the study selection process may have introduced subjective bias, potentially reducing the reliability of the results.

  Keywords: lack blinding selection process introduced subjective bias potentially reducing reliability
• Augmented myeloablative conditioning with olaparib in allogeneic hematopoietic stem cell transplantation for relapsed/refractory RUNX1::RUNX1T1-positive acute myeloid leukemia (2026) · doi

  Despite being a retrospective study with a limited sample size, the inherent limitations may undermine the reliability of the conclusions.

  Keywords: despite retrospective limited sample size inherent limitations undermine reliability conclusions