Long-term efficacy and monitoring
Research gap analysis derived from 3 medicine papers in our local library.
The gap
The long-term effects of interventions on patient outcomes are unclear, particularly for TEG monitoring in diabetes (1 month), structured oral care protocols in ICU patients (5 months), and antipsychotic dose adjustments during infections (variable duration).
Consensus across the literature
Papers collectively establish short-term efficacy but leave open the long-term sustainability and optimal monitoring parameters.
Research trend
Emerging — attention growing, methods still coalescing.
Supporting evidence — 3 representative gaps
- Detection of Hemostasis Abnormalities in Type 2 Diabetes Mellitus Using Thromboelastography (2022) · doi
The paper references hemostatic abnormality studies from Ethiopia (Asrat et al., 2019) and Indonesia (Ligita et al., 2019), but does not specify whether TEG-detected coagulation differences in type 2 diabetes vary by ethnicity, duration of diabetes, or concurrent medications (antiplatelet agents, statins). Longitudinal TEG monitoring to assess whether hemostasis parameters predict complications or respond to glycemic intervention is absent.
Keywords: thromboelastography type 2 diabetes ethnicity duration antiplatelet medications glycemic intervention longitudinal - FORMATION OF PROFESSIONAL COMPETENCIES OF 5TH–6TH YEAR STUDENTS IN THE PROCESS OF TEACHING INTERNAL MEDICINE (2026) · doi
The relatively short duration of the educational intervention may limit the generalizability of the findings.
Keywords: relatively short duration educational intervention limit generalizability - Correction: Exercise training affects hemodynamics and exercise capacity in cases of heart failure with preserved ejection fraction: a non-randomized controlled trial in individuals aged 65–80 years (2026) · doi
The intervention duration was only 5 months, leaving unclear whether longer-term effects and sustainability of improvements would persist
Keywords: intervention duration months leaving unclear whether longer term effects sustainability improvements persist
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