<ns4:p>Safe access to the most effective treatment options for <ns4:italic>Plasmodium vivax</ns4:italic> malaria are limited by the absence of accurate point-of-care testing to detect glucose-6-phosph

The gap

Consensus across the literature

Supporting evidence — 4 representative gaps

• Assessing progress and challenges towards malaria elimination in Kampong Speu, Cambodia: analysis of <i>Plasmodium vivax</i> and mixed infections, 2019-2023. (2026) · doi

  The data collected through the MIS are primarily derived from reports provided by health facilities and community- level health-care workers within Kampong Speu Province. However, this system does not include reports from military health services where malaria testing and treatment are also conducted. As a result, the overall number of reported malaria cases and the API presented in this study may be underestimated. However, national malaria programme staff we spoke to confirmed that only seven cases of P. vivax were reported from the military camps in the province from 2019 to 2023 (personal communication to KL). Therefore, we believe that the trends observed in this report are representative of the malaria trends in the province.

  Keywords: malaria health province reports military reported cases trends collected primarily derived provided facilities community level
• Assessing progress and challenges towards malaria elimination in Kampong Speu, Cambodia: analysis of <i>Plasmodium vivax</i> and mixed infections, 2019-2023. (2026) · doi

  Kampong Speu Province has shown significant progress towards eliminating malaria, but continued efforts are necessary to ensure sustainable results. Key focus areas for future interventions include: • Implementing interventions that target high- risk populations. Develop focused strategies to protect and serve populations at the highest risk of malaria, such as young adult males and forest- goers. • Engaging with vulnerable groups. Foster to community engagement and education raise awareness about malaria prevention, symptoms and treatment in collaboration with local organizations and health workers to reach underserved populations effectively. • Strengthening surveillance. Implement robust surveillance systems to track malaria cases in real time, enabling timely responses and resource allocation. • Striving to meet the 1–3–7 target. Ensure case notification within 1 day from diagnosis, reactive case detection within 3 days of notification of an index case, and foci investigation within 7 days of notification of a case with P. falciparum or an indigenous case regardless of the species. • Improving access to services. Determine whether the current prevention measures can be adapted and ensure that diagnostics and treatment are readily available and accessible in clinics, especially in remote areas. Continue to provide radical cure treatment to patients with P. vivax or mixed infections, including those with G6PD deficiency, in accordance with the latest treatment guidelines.8 By concentrating on these key strategies, Kampong Speu Province can build on its achievements and continue moving towards the goal of malaria elimination. Sustained commitment and innovation will be key to overcoming the remaining challenges. WPSAR Vol 16, No 4, 2025 | doi: 10.5365/wpsar.2025.16.4.1251 9 https://ojs.wpro.who.int/Malaria elimination progress and challenges in Kampong Speu, Cambodia, 2019–2023

  Keywords: malaria case treatment kampong speu ensure populations notification within province progress towards areas interventions target
• Optimizing G6PD testing for Plasmodium vivax case management: why sex, counseling, and community engagement matter (2020) · doi

  <ns4:p> Safe access to the most effective treatment options for <ns4:italic>Plasmodium vivax</ns4:italic> malaria are limited by the absence of accurate point-of-care testing to detect glucose-6-phosphate dehydrogenase (G6PD) deficiency, the most common human genetic disorder.

  Keywords: italic safe access effective treatment options plasmodium vivax malaria limited absence accurate point care testing
• Optimizing G6PD testing for Plasmodium vivax case management and beyond: why sex, counseling, and community engagement matter (2020) · doi

  <ns4:p>Safe access to the most effective treatment options for <ns4:italic>Plasmodium vivax</ns4:italic> malaria are limited by the absence of accurate point-of-care testing to detect glucose-6-phosphate dehydrogenase (G6PD) deficiency, the most common human genetic disorder.

  Keywords: italic safe access effective treatment options plasmodium vivax malaria limited absence accurate point care testing