How many papers support this gap analysis?

3 papers from our local library contribute to this synthesis, with an average publication year of 2024.

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biology3 papersavg year 2024quality 6/5weak evidence

Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive types of cancer and chemotherapy resistant cancer, in the development of which poorly studied cancer stem cells (CSC) and mesenchy

Research gap analysis derived from 3 biology papers in our local library.

The gap

Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive types of cancer and chemotherapy resistant cancer, in the development of which poorly studied cancer stem cells (CSC) and mesenchymal stem cells (MSC) are of great import

Consensus across the literature

Clustered from 3 gap mentions across 3 papers via embedding cosine ≥ 0.62.

Research trend

Established — well-defined area with open sub-problems.

Supporting evidence — 3 representative gaps

Diabetes-Driven Post-Translational Remodeling in Pancreatic Ductal Adenocarcinoma (2026) · doi
Diabetes mellitus (DM), particularly Type 2 DM (T2DM), is increasingly recognized as both a risk factor and an early manifestation of pancreatic ductal adenocarcinoma (PDAC), yet the molecular mechanisms bridging these conditions remain poorly understood.
Keywords: diabetes mellitus particularly type increasingly recognized risk factor early manifestation pancreatic ductal adenocarcinoma pdac molecular
CXCL12 <sup>+</sup> pericytes as drivers of lymphatic dissemination in pancreatic cancer: Integrated single-cell and spatial analysis. (2026) · doi
4126 Background: Pancreatic ductal adenocarcinoma (PDAC) exhibits poor prognosis largely due to early lymph node metastasis, yet the cellular and molecular mechanisms governing lymphatic dissemination remain incompletely understood.
Keywords: background pancreatic ductal adenocarcinoma pdac exhibits poor prognosis largely early lymph node metastasis cellular molecular
Cancer stem cells and mesenchymal stem cells in pancreatic ductal adenocarcinoma (2019) · doi
Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive types of cancer and chemotherapy resistant cancer, in the development of which poorly studied cancer stem cells (CSC) and mesenchymal stem cells (MSC) are of great importance.
Keywords: cancer stem cells pancreatic ductal adenocarcinoma pdac aggressive types chemotherapy resistant development poorly studied mesenchymal

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