The large difference in pulmonary embolism rates (1% vs 30%) may be due to limited diagnostic methods such as contrasted CT in critically ill patients.

The gap

Consensus across the literature

Supporting evidence — 3 representative gaps

• Clinical Complications in Patients with SARS-CoV-2 in a Secondary Care Hospital in Tijuana, Mexico (2022) · doi

  The large difference in pulmonary embolism rates (1% vs 30%) may be due to limited diagnostic methods such as contrasted CT in critically ill patients.

  Keywords: large difference pulmonary embolism rates limited diagnostic contrasted critically patients
• Adult Medicine Division/Internal Medicine Society of Australia and New Zealand – Orals (2011) · doi

  The study identified 2 false negative cases (2%) in V/Q SPECT-CT interpretation for pulmonary embolism detection, but did not investigate the specific imaging characteristics or patient factors that led to these false negatives. A detailed analysis comparing the imaging features of false negative PE cases with true positive cases would clarify which patient populations or anatomical presentations require alternative diagnostic approaches.

  Keywords: V/Q SPECT-CT false negative pulmonary embolism diagnostic accuracy imaging interpretation
• The Results of Thrombolytic Treatment In Patients with Massive Pulmonary Embolism (2019) · doi

  The study lacks standardized criteria for defining 'massive' pulmonary embolism and does not clearly specify diagnostic thresholds used across patients.

  Keywords: lacks standardized criteria defining massive pulmonary embolism clearly specify diagnostic thresholds used across patients