Temporal trends in declining sperm quality are documented globally, but the specific contribution of ultra-processed food consumption to this trend needs further epidemiological investigation.

The gap

Consensus across the literature

Supporting evidence — 3 representative gaps

• SPERMATOZOA DNA DAMAGE IN MEN WITH REPRODUCTIVE PROBLEMS (2022) · doi

  Different environmental and lifestyle factors may have potential risks for male reproductive health because of their possible negative effect on sperm quality indicators and genetic instability in sperm nuclei, but more comprehensive studies are needed to establish causal relationships.

  Keywords: sperm different environmental lifestyle factors potential risks male reproductive health possible negative effect quality indicators
• The impact of junk food on male fertility: therapeutic interventions targeting advanced glycation end-products and oxidative stress in mice (2026) · doi

  Temporal trends in declining sperm quality are documented globally, but the specific contribution of ultra-processed food consumption to this trend needs further epidemiological investigation.

  Keywords: temporal trends declining sperm quality documented globally specific contribution ultra processed food consumption trend needs
• Integrating multi-omics and network toxicology to identify FIS1 as a key target of environmental pollutants in male infertility (2026) · doi

  The lack of individual-level exposure data limits the ability to draw definitive conclusions about the specific pollutants that may contribute to male infertility in different environmental contexts.

  Keywords: lack individual level exposure limits ability draw definitive conclusions specific pollutants contribute male infertility different