How many papers support this gap analysis?

3 papers from our local library contribute to this synthesis, with an average publication year of 2026.

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psychology3 papersavg year 2026weak evidence

Postoperative cognitive dysfunction is a common

Research gap analysis derived from 3 psychology papers in our local library.

The gap

Postoperative cognitive dysfunction is a common complication in older surgical patients. General anesthesia may affect the central nervous system, especially in older patients. Anesthesia providers must balance the need for adequate anesthe

Evidence profile

Sourced from the stated challenges and limitations section and future-work section of the source papers, classified as general, spanning 3 journals.

Research trend

Established — well-defined area with open sub-problems.

Supporting evidence — 4 representative gaps

BIS-guided light versus deep general anesthesia on postoperative cognitive dysfunction in older patients with regional nerve block: a randomised controlled trial (2026) · Scientific Reports · doi
Postoperative cognitive dysfunction is a common complication in older surgical patients. General anesthesia may affect the central nervous system, especially in older patients. Anesthesia providers must balance the need for adequate anesthesia with the risk of cognitive dysfunction.
generalstated challengesevidence 5/5
Keywords: postoperative cognitive dysfunction common complication older surgical patients
Effects of perioperative remote ischemic conditioning on postoperative delirium and cognitive outcomes: a systematic review and meta-analysis of randomized controlled trials (2026) · Anesthesiology and Perioperative Science · doi
Postoperative delirium and cognitive dysfunction are common and debilitating complications in surgical patients. Current treatment and management options have limited effectiveness. Remote ischemic conditioning is a potential intervention, but its effects on neurocognitive outcomes are unclear.
generalstated challengesevidence 5/5
Keywords: postoperative delirium cognitive dysfunction common debilitating complications surgical
Neuroinflammation in postoperative cognitive dysfunction: the multi-target potential of esketamine in modulating microglial responses and synaptic integrity (2026) · Frontiers in Molecular Neuroscience · doi
The strength of evidence varies substantially across the proposed mechanisms. The clinical literature is limited by the heterogeneity of neurocognitive outcomes and the lack of a standardized framework for measuring postoperative cognitive dysfunction. The paper identifies a need for further research to address the gaps in the current literature.
generallimitations sectionevidence 5/5
Keywords: strength evidence varies substantially across proposed mechanisms clinical
BIS-guided light versus deep general anesthesia on postoperative cognitive dysfunction in older patients with regional nerve block: a randomised controlled trial (2026) · Scientific Reports · doi
Future studies should investigate the long-term effects of anesthesia on cognitive function. Research should explore the mechanisms by which anesthesia affects cognitive recovery. Studies should investigate the effects of anesthesia on cognitive function in different patient populations.
generalfuture-work sectionevidence 3/5
Keywords: future studies investigate long-term effects anesthesia cognitive function

Questions about this gap

Postoperative cognitive dysfunction is a common complication in older surgical patients. General anesthesia may affect the central nervous system, especially in older patients. Ane… This is supported by 4 representative gap statements extracted from 3 papers, rated weak evidence.

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