The paper identifies the need for a sustainable

The gap

Evidence profile

Sourced from the stated research gap and future-work section and stated challenges and conclusions of the source papers, classified as general, drawn from work published between 2024 and 2026, spanning 6 journals. Those papers have been cited 138 times in total.

Supporting evidence — 8 representative gaps

• GREEN SYNTHESIS OF NANOPARTICLES USING MEDICINAL PLANTS: OPPORTUNITIES AND CHALLENGES (2026) · Zenodo (CERN European Organization for Nuclear Research) · doi

  The paper identifies the need for a sustainable and eco-friendly alternative to conventional nanoparticle synthesis methods. The gap in the commercialization and clinical translation of plant-based nanoparticle synthesis is mentioned.

  generalstated research gapevidence 5/5
  Keywords: paper identifies need sustainable eco-friendly alternative conventional nanoparticle
• Comparative green synthesis of silver nanoparticles using seed and pod extracts of amomum aromaticum and their biological evaluation (2026) · Zastita materijala · doi

  Limited investigation has been conducted on how different organs of the same species may influence nanoparticle formation and biological performance. The specific plant organ used in green synthesis has not been thoroughly considered.

  generalstated research gapevidence 5/5
  Keywords: limited investigation has been conducted different organs same
• Green fabrication of copper oxide nanoparticles via Cinnamomum zeylanicum Blume bark and its role in antimicrobial, antioxidant, antidiabetic, and photocatalytic applications (2026) · Discover Chemistry · doi

  The traditional synthesis methods for nanoparticles have limitations. There is a need for sustainable and eco-friendly methods for nanoparticle synthesis. The use of plant extracts for nanoparticle synthesis is a relatively unexplored area.

  generalstated research gapevidence 5/5
  Keywords: traditional synthesis methods nanoparticles have limitations there need
• Cutting-Edge Strategies to Enhance Bioactive Compound Production in Plants: Potential Value of Integration of Elicitation, Metabolic Engineering, and Green Nanotechnology (2024) · Agronomy · cited 46× · doi

  The interactions between nanoparticles and plant systems are not fully understood. There is a need to develop standardized protocols for nanoparticle application in agriculture. The long-term effects of nanoparticles on plant physiology and the surrounding ecosystem require further research.

  generalstated research gapevidence 5/5
  Keywords: interactions between nanoparticles plant systems fully understood there
• Cutting-Edge Strategies to Enhance Bioactive Compound Production in Plants: Potential Value of Integration of Elicitation, Metabolic Engineering, and Green Nanotechnology (2024) · Agronomy · cited 46× · doi

  Future research should focus on unraveling the mechanisms underlying nanoparticle uptake, translocation, and interaction within plant cells. Additionally, there is a need to develop standardized protocols for nanoparticle application in agriculture, ensuring that their use is both safe and effective. As these technologies continue to evolve, they hold the potential for revolutionizing the production of bioactive compounds in plants, contributing to sustainable agricultural practices and the development of high-value products for the pharmaceutical, nutraceutical, and food industries.

  generalfuture-work sectionevidence 5/5
  Keywords: future research focus unraveling mechanisms underlying nanoparticle uptake
• Cutting-Edge Strategies to Enhance Bioactive Compound Production in Plants: Potential Value of Integration of Elicitation, Metabolic Engineering, and Green Nanotechnology (2024) · Agronomy · cited 46× · doi

  Optimizing the approaches for large-scale agricultural application remains a challenge. Understanding the precise interactions between nanoparticles and plant systems is a significant challenge. Ensuring the environmental and economic sustainability of these approaches is a challenge.

  generalstated challengesevidence 5/5
  Keywords: optimizing approaches large-scale agricultural application remains challenge understanding
• Green synthesis, characterization and economic evaluation of sulfur nanoparticles using Punica granatum peel extract (2026) · Discover Plants · doi

  While the present study focuses on synthesis, characterization and economic evaluation, the functional applications of these nanoparticles in areas such as agriculture, medicine and material science remain to be systematically investigated.

  generalconclusionsevidence 4/5
  Keywords: present focuses synthesis characterization economic evaluation functional applications nanoparticles areas agriculture medicine material science remain
• Harnessing biogenic nanoparticles to mitigate biotic stresses in sustainable crop production (2026) · Discover Plants. · doi

  Further research is needed to fully explore the potential of biogenic nanoparticles in agriculture. Studies should focus on the scalability and cost-effectiveness of biogenic nanoparticle synthesis. Research should also investigate the mechanisms of biogenic nanoparticle-mediated stress tolerance in plants.

  generalfuture-work sectionevidence 4/5
  Keywords: further research needed fully explore potential biogenic nanoparticles

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