The rapid emergence of antibiotic resistance is a major
Research gap analysis derived from 4 biology papers in our local library.
The gap
The rapid emergence of antibiotic resistance is a major global health concern. High costs, lengthy timelines, and high failure rates remain major challenges in modern drug discovery. The development of new, more effective, and safer antibac
Evidence profile
Sourced from the stated challenges and stated research gap of the source papers, classified as general, drawn from work published between 2024 and 2026, spanning 4 journals. Those papers have been cited 263 times in total.
Research trend
Established — well-defined area with open sub-problems.
Supporting evidence — 4 representative gaps
- Genes and physiological strategies in bacterial antibiotic resistance (2026) · Frontiers in Microbiology · doi
The emergence of antibiotic-resistant bacteria is a growing concern in modern medicine. The development of effective antibiotic therapies is challenging due to the complex interactions between bacteria and antibiotics. The study highlights the need for responsible antibiotic use to mitigate the emergence of antibiotic-resistant bacteria.
generalstated challengesKeywords: emergence antibiotic-resistant bacteria growing concern modern medicine development - Novel organophosphorus–quinolone hybrids as potential antimicrobial agents: design, synthesis, biological evaluation, and in vivo antibacterial effect in bacteria-infected zebrafish model (2026) · Molecular Diversity · doi
The development of novel antimicrobial agents with distinct chemical scaffolds and mechanisms of action is needed to address the growing problem of antimicrobial resistance. Quinolone antibiotics have limitations in their clinical application, including the development of resistance. There is a need for new antimicrobial agents with potent activity against MRSA and other bacterial pathogens.
generalstated research gapKeywords: development novel antimicrobial agents distinct chemical scaffolds mechanisms - Antimicrobial nanoparticles: current landscape and future challenges (2024) · RSC Pharmaceutics · cited 263× · doi
The need for alternative treatments to conventional antibiotics due to the rising threat of antimicrobial resistance. The lack of understanding of antimicrobial mechanisms and their real-life toxicity. The need for the development of new antimicrobial therapies with improved efficacy and reduced risk of resistance.
generalstated research gapKeywords: need alternative treatments conventional antibiotics due rising threat - Integrated in silico analysis of selected heterocyclic and chalcone derivatives as DNA gyrase B inhibitors: a multiparametric computational prioritization approach (2026) · Chemical Papers · doi
The rapid emergence of antibiotic resistance is a major global health concern. High costs, lengthy timelines, and high failure rates remain major challenges in modern drug discovery. The development of new, more effective, and safer antibacterial agents is a primary priority in modern medicinal chemistry.
generalstated challengesevidence 5/5Keywords: rapid emergence antibiotic resistance major global health concern
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