The relationship between symptoms of depression and anxiety and disease progression in multiple sclerosis is unclear
Research gap analysis derived from 3 psychology papers in our local library.
The gap
The relationship between symptoms of depression and anxiety and disease progression in multiple sclerosis is unclear. There is a need to identify people with MS at high risk of progression. The study aims to address this gap by investigating whether symptoms of depression and anxiety predict neurological disability progression.
Evidence profile
Sourced from the stated research gap and future-work section of the source papers, classified as general, drawn from work published between 2024 and 2026, spanning 3 journals.
Research trend
Established — well-defined area with open sub-problems.
Supporting evidence — 3 representative gaps
- Symptoms of depression and anxiety are early predictors of multi-domain disability progression in progressive MS (2026) · Journal of Neurology · doi
The relationship between symptoms of depression and anxiety and disease progression in multiple sclerosis is unclear. There is a need to identify people with MS at high risk of progression. The study aims to address this gap by investigating whether symptoms of depression and anxiety predict neurological disability progression.
generalstated research gapKeywords: relationship between symptoms depression anxiety disease progression multiple The relationship between affective symptoms in MS and structural and functional abnormalities in the brain is not fully understood. Prior studies have shown inconsistent results regarding the relationship between MRI findings and psychiatric comorbidities in MS. There is a need for a systematic review of existing literature to identify MRI correlates of depression and anxiety in MS patients.
generalstated research gapevidence 5/5Keywords: relationship between affective symptoms structural functional abnormalities brain- Emotional dyscontrol in multiple sclerosis: an opinion article (2024) · Frontiers in Behavioral Neuroscience · doi
investigating emotional control abilities in MS to consider potential targeted interventions, - exploring the relationship between multiple sclerosis and emotional dyscontrol, - distinguishing and separating reactive psychological problems from the psychopathology directly related to the morphological changes that occur in the brains of MS patients
generalfuture-work sectionevidence 5/5Keywords: investigating emotional control abilities consider potential targeted interventions
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