Adopt longitudinal and interventional designs
Research gap analysis derived from 3 medicine papers in our local library.
The gap
Future studies should adopt longitudinal and interventional designs to determine whether improving sleep quality can actively attenuate disease activity and accelerate HRQoL recovery.
Evidence profile
Sourced from the limitations and future work of the source papers, classified as methodology gap, spanning 2 journals.
Research trend
Established — well-defined area with open sub-problems.
Supporting evidence — 3 representative gaps
- Poor sleep quality and associated factors people living with HIV on follow-up in Benin's National Teaching Hospital: a cross-sectional study (2026) · Sleep Science and Practice · doi
The cross-sectional design captured sleep quality associations at a single time point in PLHIV, but lacks longitudinal follow-up data to establish causality between identified risk factors (depression, psychiatric comorbidities, medication adherence) and temporal changes in sleep quality over extended treatment periods.
methodology gaplimitationsevidence 5/5Keywords: cross-sectional longitudinal sleep quality PLHIV depression psychiatric comorbidities temporal - Determinants of poor sleep quality in hemodialysis patients: a multicenter cross sectional study in Sri Lanka (2026) · Frontiers in Medicine · doi
Longitudinal research designs may be utilised to examine the fluctuations in sleep quality of patients over time, influenced by factors such as dialysis vintage, dietary modifications, fluid balance, and dialysis adequacy.
methodology gapfuture workevidence 4/5Keywords: dialysis longitudinal designs utilised examine fluctuations sleep quality patients time influenced factors vintage dietary modifications - The mediating role of sleep quality in the association between inflammatory disease activity and health-related quality of life in rheumatoid arthritis (2026) · Frontiers in Medicine · doi
Future studies should adopt longitudinal and interventional designs to determine whether improving sleep quality can actively attenuate disease activity and accelerate HRQoL recovery.
methodology gapfuture workevidence 2/5Keywords: future adopt longitudinal interventional designs determine whether improving sleep quality actively attenuate disease activity accelerate
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