Open research questions in Dental Radiography and Imaging
557 gap statements mined from Dental Radiography and Imaging papers in our 7.9M-paper local library, which holds 3,432 papers on the topic — drawn mostly from each paper's own stated research gap, future-work, challenge and limitation notes, and its abstract. The ones listed below are a selection still marked open; each names the study that raised it, with a DOI link where the paper has one.
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What the literature leaves open
The study was retrospective. The study had a limited sample size of 60 patients. Discrepancies between AI-generated and clinician-derived treatment plans were observed in a subset of cases.
Unveiling AI-Augmented Periodontal Decision-Making: A Comparative Clinical Evaluation of Diagnocat-Based Radiographic Deep Learning and ChatGPT-Driven Treatment Planning Versus Clinical Expert Judgement · 2026 · DOIClustering is a particularly important limitation. The studies did not address a common clinical question, making it difficult to estimate a pooled operating point. Most nominal uncertainty estimates could not account for clustering.
Diagnostic Accuracy of Artificial Intelligence for Dental Caries Detection Across Clinical Imaging Modalities: A Systematic Review and Descriptive Synthesis · 2026 · DOIThe existing evidence has limitations, including high risk of bias and lack of external validation. There is a need for locked-model external validation and paired prospective evaluations with patient-relevant outcomes.
Diagnostic Accuracy of Artificial Intelligence for Dental Caries Detection Across Clinical Imaging Modalities: A Systematic Review and Descriptive Synthesis · 2026 · DOILimited accuracy in assessing bone defects using traditional radiographic methods. Lack of a clear distinction between radiographic findings and clinical diagnosis of furcation involvement. Need for a more comprehensive preoperative evaluation.
The application of deep learning in intelligent assessment of horizontal bone loss in mandibular first molars · 2026 · DOIThe lack of normal anatomical references in reconstructing extensive mandibular defects. The limitations of conventional methods for developing prediction models in real clinical scenarios.
Comparison of multivariate linear regression and random forest model in developing mandibular chin prediction reconstruction equation · 2026 · DOIThe study had a limited sample size of 300 professionals. The response rate was approximately 30% for specialists and 40% for non-specialists. The study did not include specialists from other fields in the construct validation phase.
Specialists’ agreement and construct validation of a visual scale for assessing mucosal healing after third molar extraction · 2026 · DOILimited studies have investigated the use of AI-based methods for predicting peri-implantitis onset. Prior studies have reported variable performance of CNN architectures in predicting peri-implantitis onset.
Accuracy of transfer learning in predicting peri-implantitis onset from intraoral radiograph: A multi-center longitudinal retrospective study · 2026 · DOIThe study identifies the need for improved accuracy and precision in guided apical surgery. The study highlights the limitations of conventional freehand techniques in guided apical surgery. The study investigates the potential of digital guides to improve the outcomes of guided apical surgery.
The gap in the current literature is the lack of comparison between 3D DICOM data and PDF cone beam computer topography reports for buccal bone height measurements. The study aims to fill this gap by investigating the effect of viewing modality on buccal bone height measurements.
Can Viewing Modality Affect Frontal Mandibular Bone Height Measurement? A Comparison Between 3D Digital Imaging and Communications in Medicine Viewer and Printed Portable Document Format Cone Beam Computer Tomography Reports · 2025 · DOIThere is a lack of proper evaluation and management of impacted wisdom teeth. The current clinical curriculum primarily focuses on simple exodontia, which may contribute to the gap.
Assessing the Management and Evaluation of Impacted Wisdom Teeth in a Dental Teaching Hospital · 2025 · DOIThe available intraoral appliances do not provide adequate anchorage. Extraoral appliances are unreliable without patient cooperation. There is a need to investigate the relationships between facial morphology and alveolar crest cortical bone thickness.
Relationship Between Facial Types and Alveolar Crest Cortical Bone Thickness and CT Values Determined by Multidetector Computed Tomography · 2025 · DOIThe need for a method that can effectively integrate high-quality semantic information from the Transformer branch into the CNN branch. The challenge of ineffective collaborative fusion between features from the CNN and Transformer dual-branch architectures.
A Dual-Stream Dental Panoramic X-Ray Image Segmentation Method Based on Transformer Heterogeneous Feature Complementation · 2025 · DOIThe importance of supervised interpretation, especially in populations with low disease prevalence or in cases where radiographic artifacts and anatomical variability may mimic pathology, was noted. The study highlighted the need for refining AI models to further enhance the detection of subtle radiographic changes in elite athletes.
In conclusion, AI has the potential to improve diagnostics and influence treatment choices, but current evidence is limited and inconsistent regarding its impact on specificity, decision quality, and cost-effectiveness.
Assessing the Role of Artificial Intelligence in Caries Detection and Clinical Decision-Making: A Scoping Review · 2026 · DOIFurther high‐quality, methodologically robust research is warranted to validate and optimize these approaches for clinical use.
Diagnostic Performance of Artificial Intelligence in Detecting Periodontal Diseases Using Cone‐Beam Computed Tomography: A Systematic Review · 2026 · DOICombined clinical‐radiographic evaluation and prospective validation are warranted.
Association Between Suspected Cemental Tears and Periodontal Breakdown: A Large Retrospective Study on Periapical Radiographs · 2026 · DOIThe study was limited to a secondary analysis of a dataset from a previous cross-sectional study. The study only accounted for information regarding the conditions defined for the goal of the study (dental caries, periodontitis and periapical lesions). The AI software was used in its standard operating mode, without manual overrides or post-processing.
The study was retrospective, - The study had a limited sample size of 110 CBCT scans, - The study only included adult patients with atrophied mandibles, - The study did not provide evidence of clinical…
CBCT-Based Anatomical Assessment of Lingual Bone Availability Relevant to the Mental Foramen Bypass Concept in Posterior Atrophied Mandibles · 2026 · DOIFurther studies are needed to investigate the clinical efficacy of the findings, - Future research should focus on the application of CBCT in implant planning and placement, - Studies should be conducted to compare the results of this study with other anatomical assessment…
CBCT-Based Anatomical Assessment of Lingual Bone Availability Relevant to the Mental Foramen Bypass Concept in Posterior Atrophied Mandibles · 2026 · DOIThe study relies on a specific dataset of CBCT images, - The model's performance may not generalize to other types of images or datasets, - The study does not provide a direct comparison with other deep learning models, - The study is limited to the diagnosis of horizontal bone loss in mandibular first…
The application of deep learning in intelligent assessment of horizontal bone loss in mandibular first molars · 2026 · DOIRefinement of the scale to improve inter-rater agreement. Further validation of the scale in different clinical settings. Investigation of the scale’s utility in other areas of dentistry.
Specialists’ agreement and construct validation of a visual scale for assessing mucosal healing after third molar extraction · 2026 · DOIInvestigating other CNN architectures, - Exploring other transfer learning approaches, - Applying the model to larger…
Accuracy of transfer learning in predicting peri-implantitis onset from intraoral radiograph: A multi-center longitudinal retrospective study · 2026 · DOIThe study was conducted at a single dental hospital, - The sample size was limited to 270 cases, - The study was retrospective, - The study relied on electronic medical records and panoramic…
Assessing the Management and Evaluation of Impacted Wisdom Teeth in a Dental Teaching Hospital · 2025 · DOILimited to 3D dental segmentation, - Requires a small proportion of labeled data, - Computational cost reduction is compared to existing self-supervised…
Multi-Encoding Contrastive Learning for Dual-Stream Self-Supervised 3D Dental Segmentation Network · 2025 · DOIIn-depth exploration of datasets, - Handling of abstract and complex data patterns, - Robust learning…
Comparison of multivariate linear regression and random forest model in developing mandibular chin prediction reconstruction equation · 2026 · DOI
Most-cited papers in Dental Radiography and Imaging
- The periapical index: A scoring system for radiographic assessment of apical periodontitis · Dental Traumatology · 1986 · 958 citations
- Detection and diagnosis of dental caries using a deep learning-based convolutional neural network algorithm · Journal of Dentistry · 2018 · 889 citations
- Cone-beam computerized tomography (CBCT) imaging of the oral and maxillofacial region: A systematic review of the literature · International Journal of Oral and Maxillofacial Surgery · 2009 · 655 citations
- Developments, application, and performance of artificial intelligence in dentistry – A systematic review · Journal of Dental Sciences · 2020 · 559 citations
- Accuracy of Cone Beam Computed Tomography and Panoramic and Periapical Radiography for Detection of Apical Periodontitis · Journal of Endodontics · 2008 · 479 citations
- Basic Erosive Wear Examination (BEWE): a new scoring system for scientific and clinical needs · Clinical Oral Investigations · 2008 · 469 citations
- The potential applications of cone beam computed tomography in the management of endodontic problems · International Endodontic Journal · 2007 · 442 citations
- Age estimation of adults from dental radiographs · Forensic Science International · 1995 · 439 citations
- Convolutional neural networks for dental image diagnostics: A scoping review · Journal of Dentistry · 2019 · 436 citations
- Cone beam computed tomography in implant dentistry: recommendations for clinical use · BMC Oral Health · 2018 · 429 citations
Most recent work
- Diamond Cut Veneers: The Faceted Monolithic Ceramic Dental Prosthesis — Concept Origin and Priority Record · PubMed · 2026
- American Dental Association and American Academy of Oral and Maxillofacial Radiology patient selection for dental radiography and cone-beam computed tomography · The Journal of the American Dental Association · 2026
- Integrating AI into Dentistry: Technical Pathways and Clinical Applications in Oral Diseases–A Comprehensive Overview · International Dental Journal · 2026
- Innovative tooth segmentation using hierarchical features and bidirectional sequence modeling · Pattern Recognition · 2026
- Dual Framework for Classification and Detection of Third Molar Impaction in Panoramic Radiographs · International Dental Journal · 2026
- Advanced deep learning techniques for classifying dental conditions using panoramic X-ray images · BMC Oral Health · 2026
- Multi-structure segmentation in CBCT volumes: The ToothFairy2 challenge · Medical Image Analysis · 2026
- Automated 3D cephalometry: A lightweight V-net for landmark localization on CBCT · Computerized Medical Imaging and Graphics · 2026
- An enhanced deep learning model for detection and classification of dental caries in panoramic radiographs · Neural Computing and Applications · 2026
- Applications for the YOLO deep learning framework in dentistry: A narrative review · Journal of Prosthodontic Research · 2026
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