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Open research questions in Medical Case Reports and Studies

186 unresolved questions extracted from the limitations and future-work sections of 299 Medical Case Reports and Studies papers in our library. Each links back to the study that raised it.

What the literature leaves open

  • There is a need to revisit the Ayurvedic anatomical concepts of Janu Sandhi and correlate them with clinical application. The paper identifies a gap in the understanding of applied anatomy in Ayurveda and its relevance to disease manifestation, diagnosis, and management.

    APPLIED ANATOMY OF JANU SANDHI IN AYURVEDA · 2026 · DOI

  • Conventional medical approaches often present limitations in managing Gridhrasi. There is a need for alternative treatments that are safe, effective, and cost-effective.

    A CLINICAL STUDY ON THE EFFECT OF VAITARANA BASTI WITH MADANAPHALA KASHAYA IN THE MANAGEMENT OF GRIDHRASI · 2026 · DOI

  • There is a need for effective treatments for ankle sprain that can reduce pain, swelling, and restricted joint mobility. Ayurvedic techniques have the potential to fill this gap.

    A SINGLE CASE STUDY ON NYAGRODHADI LEPA IN THE MANAGEMENT OF ANKLE SPRAIN (GULPHA SANDHIJA AGANTUJA SHOTHA) · 2026 · DOI

  • Amavata is a debilitating disorder with limited treatment options. The current treatment options have limited efficacy and may have adverse effects. There is a need for alternative or complementary approaches to manage Amavata.

    Ayurvedic Management of Recurrent Amavata Focusing on Ama Pachana and Functional Recovery: A Case Report · 2026 · DOI

  • Diabetic neuropathy is a complex condition, requiring a holistic approach to management. The underlying metabolic and structural imbalances must be addressed. Ayurvedic therapies, such as Shodhana, Shamana, and Rasayana, must be tailored to individual patient needs.

    DIABETIC NEUROPATHY AND KAYACHIKITSA: A COMPREHENSIVE REVIEW · 2026 · DOI

  • Presbyacusis is a major issue among elderly people. Hearing loss can be difficult to treat. There is a need for effective treatments for presbyacusis.

    A CLINICAL CASE STUDY ON KARNABADHIRYA WITH AYURVEDIC MANAGEMENT · 2026 · DOI

  • Managing migraine with aura can be challenging due to its complex pathophysiology. Conventional treatment modalities may have limited efficacy or adverse effects.

    Holistic management of Ardhavabhedaka (migraine with aura): A case report · 2026 · DOI

  • Marriage delays. Career struggles. Financial stress. Family problems. Mental pressure and lack of confidence. Repeated obstacles in important work.

    Why Kaal Sarp Dosh Happens: Causes, Effects & Remedies · 2026 · DOI

  • Amavata is a chronic inflammatory condition that affects joints, producing symptoms such as pain, swelling, stiffness, and restricted movement. The disorder shows strong similarity to rheumatoid arthritis. There is a need for a holistic approach in managing Amavata.

    AN INTEGRATIVE REVIEW OF ANATOMICAL CHANGES IN GULPHA SANDHI IN AMAVATA ACORRDING AYURVEDA AND MODERN SCIENCE · 2026 · DOI

  • The disruption of Agni and pitta can lead to various disorders. Heavy and late-night dinner can cause digestive strain and disrupt the body's natural circadian rhythm. There is a need to develop effective treatments for liver disorders.

    RASASESHA AJEERNA - LEADING TO GROSS HEPATIC DAMAGE IN LIVER BIOMARKERS(LFT)? · 2026 · DOI

  • The sudden appearance of the condition can cause concern among patients. There is a need to rule out associated systemic disorders. The integration of Ayurvedic knowledge with modern ophthalmology can be challenging.

    ARJUNA (SUBCONJUNCTIVAL HEMORRHAGE): A REVIEW ARTICLE · 2026 · DOI

  • The chronic and severe nature of Ekakushta makes it a challenging condition to treat. The lack of effective treatment options for Ekakushta is a significant challenge.

    ROLE OF PANCHAKARMA AND ŚAMANA CHIKITSA IN THE MANAGEMENT OF EKAKUṢṬHA – A CASE REPORT · 2026 · DOI

  • The condition can lead to digital ulcers, ischemia, and functional disability. Conventional care relies on vasodilatory pharmacotherapy, but long-term compliance is often limited.

    A CASE STUDY-ON RAYNAUDS PHENOMENON · 2026 · DOI

  • Allergic conjunctivitis is a common clinical condition. The disease can cause significant discomfort to the patient. There is a need for effective treatment modalities.

    AYURVEDIC MANAGEMENT OF ALLERGIC CONJUNCTIVITIS IN 30 YEARS OLD PATIENT: A CASE STUDY · 2026 · DOI

  • The chronic nature of Bhagandara makes it difficult to manage. The tendency for recurrence and difficulty in management are major challenges. The lack of understanding of the effectiveness of Ksharasutra therapy is a challenge.

    BHAGANDARA (FISTULA-IN-ANO) - A REVIEW OF LITERATURE · 2026 · DOI

  • The increasing prevalence of cervical spondylosis among younger, working-age adults. The need to consider alternative treatments for degenerative disorders. The importance of incorporating Ayurvedic principles into treatment protocols.

    AYURVEDIC MANAGEMENT OF GREEVA SANDHIGATA VATA (CERVICAL SPONDYLOSIS): A SINGLE CASE STUDY · 2026 · DOI

  • Substantial variability remains in how individuals respond to medications. Genetic variation is a significant contributor to differences in drug response. Traditional prescribing methods often overlook biological diversity.

    AYURVEDIC APPROACH ON MENORRHAGIA: ASRIGDARA · 2026 · DOI

  • Delayed wound healing due to systemic factors or microbial invasion. Severe systemic barriers such as anemia and hypoproteinemia. Limited treatment options for geriatric patients.

    AYURVEDIC MANAGEMENT OF DUSHTA VRANA ASSOCIATED WITH BILATERAL LOWER LIMB EDEMA IN A GERIATRIC PATIENT: A CASE REPORT · 2026 · DOI

  • UTIs are common bacterial infections that can be difficult to treat. Conventional treatments may not always be effective. There is a need for alternative approaches to managing UTIs.

    AYURVEDIC MANAGEMENT OF MUTRAKRICCHA (URINARY TRACT INFECTION): A CASE REPORT · 2026 · DOI

  • Persistent neurological deficits and functional dependence in patients with chronic post-stroke hemiplegia. Limited treatment options for comprehensive rehabilitation.

    MANAGEMENT OF PAKSHAGHATA WITH MUSTADI RAJA YAPANA BASTI: A CASE REPORT · 2026 · DOI

  • The condition is degenerative and affects the knee joint. The symptoms are debilitating and affect daily activities. There is a need to find effective treatments.

    EFFICACY OF MADHUTAILIKA BASTI IN JANUSANDHIGATVAT: A CASE REPORT · 2026 · DOI

  • Vitiated Vata dosha along with Kapha dosha leads to Srotorodha and further ignorance of this condition leads to Badhirya. Hearing impairment means complete or partial loss of the ability.

    A CLINICAL STUDY TO EVALUATE THE EFFICACY OF ERANDADI TAILA KARNAPOORNA ALONG WITH GOGHRITPANA IN THE MANAGEMENT OF KARNA BADHIRYA (SENSORINEURAL HEARING LOSS) · 2026 · DOI

  • The study identifies the challenge of addressing emotional imbalance in the treatment of gynecological disorders. The authors highlight the need for a holistic approach to gynecological health care, incorporating both physical and emotional aspects.

    UNDERSTANDING EMOTIONAL ETIOLOGY IN FEMALE REPRODUCTIVE DISORDERS · 2026 · DOI

  • The study faced challenges in terms of limited follow-up period and lack of control group. The patient's prior medical history and current symptoms presented challenges in terms of treatment selection and outcome measurement.

    Ayurvedic Management of Shweta Pradar (Leucorrhoea) Using Nagakeshar Choorna with Takra and Yoni Dhoopan with Yava and Guggul Choorna: A Case Report · 2026 · DOI

  • The study is a single case report with no control group. The follow-up period was limited to seven days. The study did not document long-term follow-up.

    Ayurvedic Management of Shweta Pradar (Leucorrhoea) Using Nagakeshar Choorna with Takra and Yoni Dhoopan with Yava and Guggul Choorna: A Case Report · 2026 · DOI

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186 open questions have been extracted from the limitations and future-work passages of 299 Medical Case Reports and Studies papers in our library. Each one below links back to the study that raised it, so you can read the original claim in context.

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