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Open research questions in Women's cancer prevention and management

80 unresolved questions extracted from the limitations and future-work sections of 771 Women's cancer prevention and management papers in our library. Each links back to the study that raised it.

What the literature leaves open

  • A necessidade de avaliar a efetividade das cirurgias minimamente invasivas no tratamento do câncer de mama. A falta de estudos que compararam as abordagens minimamente invasivas com as técnicas convencionais.

    CIRURGIAS MINIMAMENTE INVASIVAS NO CÂNCER DE MAMA: REVISÃO INTEGRATIVA · 2026 · DOI

  • There is a need to identify the main challenges related to cervical cancer screening and early diagnosis among older women in Brazil. The current barriers to screening and prevention programs need to be addressed.

    CÂNCER DO COLO DO ÚTERO EM MULHERES IDOSAS: DESAFIOS NO RASTREAMENTO E DIAGNÓSTICO PRECOCE NO BRASIL · 2026 · DOI

  • The development of educational technology on gender and sexuality for primary health care professionals is a complex task. It requires a deep understanding of the needs of health care professionals and the LGBTQIAPN+ community. The technology must be accessible and easy to use.

    Creation of educational technology on gender and sexuality for primary health care professionals / Criação de tecnologia educacional sobre gênero e sexualidade para profissionais da atenção primária à saúde · 2026 · DOI

  • There is a need for educational technology on gender and sexuality for primary health care professionals. The current literature highlights the importance of inclusive practices in primary health care, but there is a lack of resources to support this.

    Creation of educational technology on gender and sexuality for primary health care professionals / Criação de tecnologia educacional sobre gênero e sexualidade para profissionais da atenção primária à saúde · 2026 · DOI

  • The study faced challenges in terms of sample size and generalizability. The study highlights the importance of addressing the complex needs of elderly patients with cancer.

    ANÁLISE DO RISCO DE FRAGILIZAÇÃO EM IDOSOS ONCOLÓGICOS POR AVALIAÇÃO GERIÁTRICA COMPACTA DE 10 MINUTOS (AGC-10) · 2026 · DOI

  • Limited access to healthcare services. Lack of education and awareness about cervical cancer. Cultural and socioeconomic barriers to healthcare access.

    Cervical cancer: Riverside women’s knowledge in the Brazilian Amazon about preventive measures · 2026 · DOI

  • The study faced challenges in terms of the limited sample size and the non-experimental research design. The research highlights the importance of considering the social context in which educational experiences take place.

    Un proyecto social desde dos institutos de Secundaria de Santa Coloma de Gramenet (2022-2025). Una lucha contra el cáncer infantil. · 2026 · DOI

  • Structural inequalities in access to health services. Limited access to screening and diagnosis in rural and poor areas. Impact of COVID-19 on screening and diagnosis.

    AS DESIGUALDADES NO RASTREAMENTO DO CÂNCER DE COLO DO ÚTERO: ANÁLISE EPIDEMIOLÓGICA COMPARATIVA ENTRE MACRORREGIÕES DO PARANÁ E REGIÕES NORTE E NORDESTE DO BRASIL (2016–2025) · 2026 · DOI

  • The rarity of PCL makes it challenging to conduct large-scale studies. The aggressive nature of PCL makes it difficult to achieve long-term survival. The lack of awareness and understanding of PCL among healthcare professionals may lead to delayed diagnosis and treatment.

    Leucemia de células plasmáticas: una serie de casos · 2026 · DOI

  • The management of advanced rhinophyma. The need for significant aesthetic and functional improvement. The importance of patient satisfaction with the treatment outcome.

    Associação de laser ablativo, luz intensa pulsada e cauterização química no tratamento de rinofima: relato de caso · 2026 · DOI

  • The paper identifies the challenge of balancing survival and tolerability. The review highlights the importance of adjusting treatment according to patient particularities. The paper acknowledges the lack of randomized controlled trials.

    Quimioterapia paliativa no câncer avançado · 2026 · DOI

  • Cholangiocarcinoma is a rare and aggressive form of cancer. The IDH1 mutation is a common genetic alteration in cholangiocarcinoma. The current treatment options for cholangiocarcinoma are limited.

    Revisão sistemática de ensaios clínicos randomizados de pacientes com colangiocarcinoma mutante IDH1 R132 tratados com ivosidenibe · 2026 · DOI

  • Limited access to preventive services. Lack of knowledge and awareness about breast self-examination. Emotional barriers to breast self-examination.

    Impacto de Programa Educativo de Concientización y Práctica de Autoexploración Mamaria para Adolescentes · 2026 · DOI

  • The study identifies technical challenges in implementing AI-based mammography interpretation, including the need for high-quality datasets and expertise in deep learning.

    DA TELA AO DIAGNÓSTICO: COMO A INTELIGÊNCIA ARTIFICIAL ESTÁ REDEFININDO A INTERPRETAÇÃO MAMOGRÁFICA NO RASTREAMENTO DO CÂNCER DE MAMA · 2026 · DOI

  • The lack of understanding of the therapeutic itineraries of women with cancer in the Amazonas state. The need to address the geographical, logistical, and cultural barriers to improve cancer treatment in the Amazonas state.

    REDE DE ATENÇÃO ONCOLÓGICA NO AMAZONAS: LÓGICAS TERRITORIAIS E VAZIOS ASSISTENCIAIS · 2026 · DOI

  • La falta de conocimiento sobre los síntomas y factores de riesgo es una barrera crítica para la prevención. Existe un déficit significativo de información en la población estudiada respecto al cáncer colorrectal.

    Nivel de conocimiento sobre cáncer colorrectal, factores de riesgo y medidas preventivas en usuarios de un hospital de referencia en Paraguay · 2026 · DOI

  • The paper identifies a gap in the understanding of the risk factors for pathological scarring. The paper aims to address this gap by reviewing the literature and identifying the risk factors.

    Factores de riesgo asociados al desarrollo de cicatrización patológica en pacientes con heridas cutáneas · 2026 · DOI

  • The study identifies challenges related to the heterogeneity of the included studies and the limited evidence on the effectiveness of supplementary ultrasound. The challenges also include the potential for false positives and the need for operator-dependent skills.

    Precisión diagnóstica de la ecografía mamaria suplementaria en el cribado de cáncer de mama en mujeres con mamas densas · 2026 · DOI

  • The study acknowledges the heterogeneity of the included studies, which limited the ability to conduct a quantitative meta-analysis. The review only included studies published in English, Spanish, or Portuguese, which may have introduced language bias.

    Precisión diagnóstica de la ecografía mamaria suplementaria en el cribado de cáncer de mama en mujeres con mamas densas · 2026 · DOI

  • La evidencia sobre los perfiles histomorfológicos e inmunohistoquímicos diferenciados estaba fragmentada. Faltaba una revisión integrativa que comparara estas características.

    Características histomorfológicas e inmunohistoquímicas de los tumores de mama en pacientes con mutaciones BRCA1 y BRCA2: Una revisión integrativa de la literatura · 2026 · DOI

  • Paraguay lacked a detailed epidemiological overview of cancer. There is a need to investigate subnational environmental or occupational risk factors.

    Tendencias epidemiológicas y distribución geodemográfica del cáncer en el Paraguay, 2015–2023: Un análisis basado en registros nacionales · 2026 · DOI

  • Limited evidence for some non-hormonal options. Small sample sizes and short follow-up periods in existing studies. Need for more research to establish the efficacy of these options.

    Ressecamento Vaginal na Menopausa: Opções Não-Hormonais · 2026 · DOI

  • The study aims to address the gap in knowledge regarding the comparison of femtosecond laser-assisted facoemulsification with manual facoemulsification in terms of endothelial cell loss. The review seeks to synthesize scientific evidence on the efficacy, safety, and clinical outcomes of the two techniques.

    FACOEMULSIFICAÇÃO ASSISTIDA POR FEMTOSSEGUNDO VERSUS MANUAL NA PERDA ENDOTELIAL EM CATARATAS DENSAS · 2026 · DOI

  • Delayed diagnosis. Limited access to diagnostic and therapeutic facilities. Lack of awareness and education on bone tumors.

    Profil Epidémiologique, Clinique, Paraclinique et Thérapeutique des Tumeurs Osseuses au Burkina Faso : Une Etude Rétrospective de 12 Ans à Bobo-Dioulasso · 2026 · DOI

  • The study faced challenges in terms of data quality and availability. There is a need to improve detection and registration capabilities.

    Tendencias epidemiológicas y distribución geodemográfica del cáncer en el Paraguay, 2015–2023: Un análisis basado en registros nacionales · 2026 · DOI

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80 open questions have been extracted from the limitations and future-work passages of 771 Women's cancer prevention and management papers in our library. Each one below links back to the study that raised it, so you can read the original claim in context.

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