Open research questions in Biomedical and Engineering Education
166 gap statements mined from Biomedical and Engineering Education papers in our 7.9M-paper local library, which holds 1,007 papers on the topic — drawn mostly from each paper's own stated research gap, future-work, challenge and limitation notes, and its abstract. The ones listed below are a selection still marked open; each names the study that raised it, with a DOI link where the paper has one.
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What the literature leaves open
Women's health involves discussing topics like menstruation, pregnancy, sexual function, and intimate medical procedures that some students find uncomfortable. There is a need to establish guidelines for respectful and professional discussion, and to set expectations early that the course covers sensitive topics.
A Framework for Women’s Health Engineering Education: Pedagogical Foundations and Practical Implementation · 2026 · DOIThe lack of educational integration into interdisciplinary disciplines in STEM education has hindered advances in women's health. Women's health research and education is a taboo and unprioritized topic. There is a need for a framework that incorporates design-based learning and laboratory research modules in women's health engineering education.
A Framework for Women’s Health Engineering Education: Pedagogical Foundations and Practical Implementation · 2026 · DOIFinally, to comprehensively consider the universal applicability of the research conclusions, existing research results still need to be validated in online courses, vocational training programs, and various institutions with a more diverse student composition.
Digital Twin-Enhanced Programming Education: An Empirical Study on Learning Engagement and Skill Acquisition · 2025 · DOIAs a final note, it is to be reminded that the course where the escape room and the project-based learning activities where implemented as an active evaluation scheme had 25 students, so the sample size of this study is limited to these scholars.
While further research is needed to quantify the impact of VL on knowledge acquisition in such a short course, our study reveals the potential of VL to rapidly reshape student perspectives and attitudes. Using semi-open questions to integrate perceptions in choice models.
Implementation of Biotechnology Applied to Medicine Course Using Virtual Laboratories: Perceptions and Attitudes of Students · 2024 · DOIFuture research should examine whether and how staged or follow-up models of innovation education influence professional practice, interprofessional collaboration, faculty capacity-building, and the development or implementation of innovation projects over time.
Advancing Evidence-Based Health Innovation in Brazil: A Qualitative Program Evaluation of a Binational Educational Initiative to Build Interprofessional Capacity · 2026 · DOIOne limitation of this study is that the digital platform was implemented exclusively within the pathology discipline and did not extend to other subjects that rely on microscopic slide analysis, such as cytopathological diagnosis.
Developing and Evaluating a Digital Pathology Platform for Veterinary Students: A Case Study in Romania · 2025 · DOIFuture research should address this gap by exploring the moderating or mediating roles of external dihttps://doi.
From Mindset to Action: Bridging the Intention–Action Gap Among Generation Z Students in a Post-Transition Economy · 2026 · DOIEvaluate Performing further research on what texture can meet consumer needs and modifying product accordingly.
Integrating Human-Centered Design into Undergraduate STEM Capstone Courses: A Food Product Development Case Study · 2025 · DOIThe study did not have direct industry collaboration. The course had a limited number of students (25). The study was conducted over a short period (one quartile, 10 weeks).
Exploring the applications of plasma physics in the semiconductor industry through challenge-based learning · 2026 · DOIFurther studies can explore the application of CBL in other fields, such as nanoelectronics, biotechnology, and renewable energy. Future research can investigate the long-term effects of CBL on student engagement and skill development. The study's findings can be used to inform the design of similar courses in STEM disciplines.
Exploring the applications of plasma physics in the semiconductor industry through challenge-based learning · 2026 · DOIThe need to design therapeutics to treat two patients-both the mother and the fetus-without sacrificing safety and efficacy for either.
Opportunities and barriers for innovation at the interface of engineering and maternal-fetal medicine · 2026 · DOIThe development of safe and effective maternal-fetal therapeutics is significantly hindered by chronic underfunding and sociopolitical stigmas. Interdisciplinary collaboration is required to design accessible therapeutics.
Opportunities and barriers for innovation at the interface of engineering and maternal-fetal medicine · 2026 · DOISignificant challenges remain in experimental and computational models. The complexity of research questions is increasing, requiring more advanced experimental tools. Current models are limited by their inability to integrate biomechanical and biochemical parameters.
The limited study of HealthTech accelerators compared to other fields. The lack of co-design training and support in HealthTech accelerators. The need for further research on the value of co-design in HealthTech innovation.
The paper identifies the need for integrating 'black box' models into research and clinical workflows. The paper highlights the need for ensuring data privacy and mitigating biases in AI algorithms. The paper discusses the regulatory and liability issues associated with the use of AI in digital health and bioengineering.
The need to examine the interdependencies and infrastructural arrangements between human and non-human actors. The importance of understanding the valuation of some forms of life over others.
Introduction to the special issue: The Near Human in life science, biomedicine, and care · 2026 · DOIThe literature has mostly focused on studying open innovation from the perspective of firms. There is a need to analyze open innovation in other contexts, such as universities.
Future research should focus on empirical validation of the constructal theory. Future research should explore the application of the constructal theory to various fields, including human health and education.
There is a lack of guidance on pedagogical approaches for cultivating technological literacy in authentic learning environments. The current education system lacks authentic learning environments.
Beyond Technological Literacy: Why Biomedical Laboratory Science Education Needs Authentic STEM-Based Learning Experiences · 2026 · DOIContinuously learning health systems sustained by seamless, real-time, iterative data flows and optimization Predictive modeling and personalized care AI as active clinical collaborator (pattern recognition, risk stratification, longitudinal planning) within governance structures, not as passive assistant for routine task automation Redistribution of cognitive tasks enabling focus on judgment, empathy…
Further development of experimental tools to study complex interactions among individual constituents. Integration of biomechanical and biochemical parameters in models. Application of systems-based approaches to develop personalized therapies and medical devices.
Exploring the value of co-design in maximising the impact of HealthTech innovations. Investigating the effectiveness of co-design training and support in HealthTech accelerators. Studying the challenges and limitations of introducing co-design into fast-paced accelerator environments.
The development of clinically integrated, regulated, and scalable digital health solutions for children and young people remains limited - Few child-focused technologies advance beyond early prototypes or small feasibility studies to achieve real-world…
Co-creating care: Involving children, young people, and families in paediatric medical device innovation · 2026 · DOIIn this vein, future research should examine how biodesign LMs’ hybrid roles can be better recognised and supported – including not only how institutions might develop more intentional professional frameworks that reflect the distinctive demands of managing workspaces for a dynamic interdisciplinary field, but also how the research and user communities can better recognise and advocate for the value of these hybrid…
Most-cited papers in Biomedical and Engineering Education
- A New Initiative on Precision Medicine · New England Journal of Medicine · 2015 · 4,439 citations
- Biopower Today · BioSocieties · 2006 · 951 citations
- Grand Challenges and Inductive Methods: Rigor without Rigor Mortis · Academy of Management Journal · 2016 · 939 citations
- Biomedicalization: Technoscientific Transformations of Health, Illness, and U.S. Biomedicine · American Sociological Review · 2003 · 922 citations
- Digital Twins: From Personalised Medicine to Precision Public Health · Journal of Personalized Medicine · 2021 · 488 citations
- Biotechnology: The University-Industrial Complex · The Journal of Higher Education · 1988 · 433 citations
- The Biomedicalization of Aging: Dangers and Dilemmas · The Gerontologist · 1989 · 280 citations
- Digital twins in medicine · Nature Computational Science · 2024 · 251 citations
- The Biotechnical Embrace · Culture Medicine and Psychiatry · 2001 · 207 citations
- Fundamentals of Aerospace Medicine · Military Medicine · 1986 · 193 citations
Most recent work
- Advancing Problem-Based Learning in Biomedical Engineering in the Era of Generative AI · IEEE Transactions on Education · 2026
- Entrepreneurship education for nurses and healthcare professionals: A scoping review and future research agenda · Nurse Education in Practice · 2026
- Promoting engagement in embryology through gamified student‐developed small group sessions · Anatomical Sciences Education · 2026
- Clinical and translational science award hubs in learning health systems: development of the engine-drivetrain model · Journal of Translational Medicine · 2026
- Introduction to the special issue: The Near Human in life science, biomedicine, and care · BioSocieties · 2026
- Cocreating societal impact through transdisciplinary, challenge-based learning · The International Journal of Management Education · 2026
- Bridging functional bionanomaterials and the clinic: strategic communication as a translational enabler · Journal of Nanobiotechnology · 2026
- Tracing the rise of biomedical foundation models · Nature Biotechnology · 2026
- Cultivating health science education innovation: the RISE Innovator Development Program · Academic Medicine · 2026
- Medical device development and innovation for rare and pediatric populations: a global landscape overview · Orphanet Journal of Rare Diseases · 2026
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