Open research questions in Health Promotion and Cardiovascular Prevention
131 gap statements mined from Health Promotion and Cardiovascular Prevention papers in our 4.5M-paper local library, which holds 889 papers on the topic — drawn mostly from each paper's own stated research gap, future-work, challenge and limitation notes, and its abstract. The ones listed below are a selection still marked open; each names the study that raised it, with a DOI link where the paper has one.
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What the literature leaves open
Participants showed relatively high knowledge regarding hypertension and type 2 diabetes, but markedly low awareness of cardiovascular disease risk. Fewer than half of participants correctly answered key CVD items. The study identified a domain-specific gap in CVD literacy.
Cardiovascular Risk Awareness Among Adults in the Northern Border Region of Saudi Arabia: A Cross-Sectional Study with Emphasis on Hypertension and Type 2 Diabetes · 2026 · DOIThe study faces the challenge of using aggregated annual health examination reports, which may limit the analysis to the annual level. It must account for sex-specific differences in health findings. The study needs to evaluate temporal trends in major health findings over a four-year period.
Four-year trends in health findings among hospital staff an ecological time-series study 2022–2025 · 2026 · DOIFurther studies could investigate the underlying causes of the observed sex-specific differences in health findings. Longitudinal follow-up studies could be conducted to track individual health outcomes over time.
Four-year trends in health findings among hospital staff an ecological time-series study 2022–2025 · 2026 · DOISince GPs currently rarely measure waist circumference, inclusion in guidelines and addressing identified barriers and facilitators is warranted.
Little is known about recent racial/ethnic disparities in populations with high AWV completion.
Disparities in Medicare Annual Wellness Visits After a Systemwide Quality Improvement Initiative: A Serial Cross-sectional Analysis · 2025 · DOIHIGHLIGHTS: Data are lacking on use of cognitive test during Medicare's Annual Wellness Visit (AWV).
Usage patterns of cognitive assessments during Medicare's Annual Wellness Visit: A national survey · 2025 · DOIMedicare's Annual Wellness Visit (AWV) is a logical opportunity for early detection of cognitive impairment, but recent data for uptake and cognitive assessments during it are lacking.
Usage patterns of cognitive assessments during Medicare's Annual Wellness Visit: A national survey · 2025 · DOIFuture research should focus on understanding the impact of migration on health behaviours overtime and developing effective interventions strategies to reduce the risk of CVD in this underserved population.
Cardiovascular preventive service access challenges among African immigrants: a discussion paper · 2025 · DOIRisk prediction models for cardiovascular diseases (CVDs) have been widely applied in clinical practice and in designing prevention policies globally, yet their accuracy across different regions with distinct epidemiological profiles remains uncertain.
Regional variations in cardiovascular risk predictions: a comparative analysis of Framingham, SCORE2, and WHO models across 53 countries · 2025 · DOIThe extent by which poor performance on prevention measures and public health policies in the USA could be contributing to this issue is not well understood.
Larger prospective or randomized studies are warranted to confirm long-term benefits on diagnosis, care engagement, and cardiometabolic outcomes.
Workplace-Based Glucose Screening for Type 2 Diabetes in French Civil Servants: Prospective Observational Cohort Study · 2025 · DOIThe findings suggest that merely informing individuals of their overweight or obese status and implementing light-touch interventions are insufficient to significantly reduce BMI or drive sustained behavior change.
Community-Based BMI Screening for Overweight and Obesity in Adults Aged 35 Years and Older in Malaysia: Regression Discontinuity Analysis · 2025 · DOICommunity-based BMI screening may enhance awareness of weight status, but its effectiveness remains uncertain.
Community-Based BMI Screening for Overweight and Obesity in Adults Aged 35 Years and Older in Malaysia: Regression Discontinuity Analysis · 2025 · DOIThe association of alcohol consumption with elevated CVD risk needs to be further studied in longitudinal studies in representative populations, notably among Sweden's diverse ethnic groups.
The estimated 10-year risk of first-onset cardiovascular disease in Swedish-born and non-Swedish-born primary healthcare patients · 2024 · DOIJapan has implemented a national lifestyle guidance intervention programme for potential metabolic syndrome among adults aged 40-74 years; however, there is limited evidence regarding the causal impact of this intervention.
Effect of the national lifestyle guidance intervention for metabolic syndrome among middle-aged people in Japan · 2024 · DOIThere is a need to evaluate the health status of non-physician university hospital workers during the COVID-19 pandemic.
Health Status of Non-Physician University Hospital Workers During the COVID-19 Pandemic: Findings from Periodic Health Examinations in 2020–2021 · 2026 · DOILack of understanding of primary, secondary, and tertiary prevention contributes to low levels of CVD prevention and early detection. There is a need for effective strategies to increase public awareness of cardiovascular disease prevention.
Health Education in Primary, Secondary, and Tertiary Prevention Efforts of Cardiovascular Disease in the Community · 2026 · DOIReducing the burden of CVD equitably remains a challenge. Disparities in care and outcomes endure across diverse populations.
Future research can focus on replicating the program in other settings to promote preventive healthcare. Further studies can investigate the effectiveness of community-based health screenings in reducing the risk of noncommunicable disease complications.
Promoting Preventive Care: Social Health Screening during the Nutrition House Inauguration · 2026 · DOIThe high prevalence of non-communicable diseases and low public awareness of the importance of early health detection highlight the need for community-based interventions.
Promoting Preventive Care: Social Health Screening during the Nutrition House Inauguration · 2026 · DOIAwareness of cardiovascular risk within the broader community and among high-risk subgroups remains suboptimal. Clinical encounters and public health campaigns may have conveyed core information about primary diagnoses more effectively than about the cumulative, often asymptomatic nature of macrovascular complications.
Cardiovascular Risk Awareness Among Adults in the Northern Border Region of Saudi Arabia: A Cross-Sectional Study with Emphasis on Hypertension and Type 2 Diabetes · 2026 · DOIHowever, it does not account for ethnicity or socioeconomic status, known to affect CVD risk.
The estimated 10-year risk of first-onset cardiovascular disease in Swedish-born and non-Swedish-born primary healthcare patients · 2024 · DOIBarriers to accessing preventive health services among community members included insufficient information, misconceptions, and the dynamics of patient-physician relationships.
Understanding the utilization of preventive health services for non-communicable diseases: a qualitative study with community members and family physicians · 2025 · DOIThe study aims to assess changes in selected lipid parameters between the first and repeated examination in clients after completing a preventive intervention.
Opakované návštevy klientov v Poradni zdravia a ich asociácia so zmenami lipidových parametrov · 2026 · DOIPrevious reviews have addressed statin10–12,14 or antihypertensive15–18 use and included ≥ socio-demographic group differences, but findings are limited by their vintage (most are 10 years old), inclusion of trial and observational data…
Discontinuation of antihypertensive and lipid-lowering medication in primary care: a systematic review of observational data and sociodemographic differences · 2026 · DOI
Most-cited papers in Health Promotion and Cardiovascular Prevention
- 2021 ESC Guidelines on cardiovascular disease prevention in clinical practice · European Heart Journal · 2021 · 6,153 citations
- Prevention of chronic disease in the 21st century: elimination of the leading preventable causes of premature death and disability in the USA · The Lancet · 2014 · 1,115 citations
- Influence of context effects on health outcomes: a systematic review · The Lancet · 2001 · 1,018 citations
- Latent Class Analysis: An Alternative Perspective on Subgroup Analysis in Prevention and Treatment · Prevention Science · 2011 · 1,007 citations
- Why is changing health-related behaviour so difficult? · Public Health · 2016 · 886 citations
- ESTIMATING PREVALENCE FROM THE RESULTS OF A SCREENING TEST · American Journal of Epidemiology · 1978 · 840 citations
- PROPORTION OF DISEASE CAUSED OR PREVENTED BY A GIVEN EXPOSURE, TRAIT OR INTERVENTION1 · American Journal of Epidemiology · 1974 · 828 citations
- Contribution of job control and other risk factors to social variations in coronary heart disease incidence · The Lancet · 1997 · 824 citations
- The science of prevention: A conceptual framework and some directions for a national research program. · American Psychologist · 1993 · 811 citations
- Efficacy and effectiveness trials (and other phases of research) in the development of health promotion programs · Preventive Medicine · 1986 · 509 citations
Most recent work
- Adult obesity and risk of severe infections: a multicohort study with global burden estimates · The Lancet · 2026
- Non-emerging primary trial results from the Bandim health project · Vaccine · 2026
- Hospitalizations and Mortality Among Medicare Beneficiaries at Cardiovascular Risk · Journal of the American College of Cardiology · 2026
- Strengthening cardiovascular disease prevention in Europe · The Lancet Public Health · 2026
- Association of the NHS Health Check with all-cause mortality: a longitudinal cohort study in primary care · British Journal of General Practice · 2026
- The line is drawn, the fate is cast: urban–rural inequalities in the timing of initial health check-ups in China · Frontiers in Sociology · 2026
- Observed incidence is not biologic risk · Annals of Allergy Asthma & Immunology · 2026
- Primary Care Providers' Perspectives on Telehealth Medicare Annual Wellness Visits for Older Adults in a Midwestern Health System · Journal of the American Geriatrics Society · 2026
- Annual Wellness Visits and Timing of Advance Care Planning Among Medicare Beneficiaries With Cognitive Impairment · Journal of the American Geriatrics Society · 2026
- Improving Follow‐Up After Fall Risk Screening: A Quality Improvement Initiative in Primary Care After the Medicare Annual Wellness Visit · Journal of the American Geriatrics Society · 2026
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