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Open research questions in Healthcare during COVID-19 Pandemic

47 unresolved questions extracted from the limitations and future-work sections of 375 Healthcare during COVID-19 Pandemic papers in our library. Each links back to the study that raised it.

What the literature leaves open

  • The study identifies a gap in the analysis of mortality due to acute myocardial infarction in Brazil, particularly in terms of sociodemographic and regional variables.

    Análise do perfil de mortalidade por infarto agudo do miocárdio no Brasil (2018–2022) · 2026 · DOI

  • The paper identifies challenges in applying emotional intelligence in public services. These include cultural and institutional barriers. It also mentions the need for leadership and personnel development.

    INTELIGÊNCIA EMOCIONAL COMO FERRAMENTA ESTRATÉGICA PARA A GESTÃO DE PESSOAS NO SERVIÇO PÚBLICO: MELHORIA DO CLIMA ORGANIZACIONAL E DA QUALIDADE DO ATENDIMENTO AO CIDADÃO · 2026 · DOI

  • The study highlights the challenge of addressing diabetes mellitus to reduce its economic impact. The study implies the need for strategies of prevention, early diagnosis, and strengthening of primary care.

    IMPACTO ECONÔMICO DAS INTERNAÇÕES POR DIABETES MELLITUS: ANÁLISE DA 10ª REGIONAL DE SAÚDE DO PARANÁ, ESTADO DO PARANÁ E BRASIL (2018–2023) · 2026 · DOI

  • The transmission of the coronavirus is mainly through contact with infected people. Adolescents are as susceptible to infection as adults and the elderly. There is a lack of understanding of the clinical, epidemiological, and demographic profile of adolescents with covid-19.

    Clinical, epidemiological, and demographic profile of adolescents with covid-19 in Divinópolis, central-west region of Minas Gerais · 2026 · DOI

  • Gaps in professional training and limited knowledge of the Clinical Protocol and Therapeutic Guidelines. Low clinical suspicion and uncertainties regarding notification of chronic Chagas disease. Limited access to healthcare services, particularly in areas with higher endemicity.

    Management of Chagas Disease in Primary Health Care: Challenges Faced by Physicians in Areas with Higher and Lower Endemicity in Brazil · 2026 · DOI

  • The COVID-19 pandemic has posed significant challenges to global health systems. The relationship between comorbidities and COVID-19 outcomes is complex and requires further study.

    VIGILÂNCIA DE ÓBITO POR COMORBIDADES DA COVID-19 EM PAÇO DO LUMIAR – MA, BRASIL · 2026 · DOI

  • La falta de una guía práctica para la toma de decisiones clínicas en la angina inestable. La necesidad de identificar las variables clínicas que permitan predecir el riesgo de eventos intrahospitalarios mayores en la angina inestable.

    Las variables clínicas predicen infarto y muerte en la angina inestable · 2026 · DOI

  • The increasing burden of aortic valve stenosis in Chile. Limited access to healthcare services for patients with aortic valve stenosis. The need for healthcare planning to address the increasing hospital discharge rate.

    Tasa de egresos hospitalarios de pacientes con estenosis de la válvula aórtica durante el periodo 2021-2024 en Chile · 2026 · DOI

  • Further studies should investigate the causes of the increasing hospital discharge rate for aortic valve stenosis in Chile. Research should focus on developing strategies to reduce the burden of aortic valve stenosis in Chile.

    Tasa de egresos hospitalarios de pacientes con estenosis de la válvula aórtica durante el periodo 2021-2024 en Chile · 2026 · DOI

  • The effect of preinfarction angina on infarct size is not fully understood. The mechanisms underlying the association between preinfarction angina and infarct size are not fully elucidated.

    La angina previa limita el tamaño del infarto · 2026 · DOI

  • The paper identifies a gap in the understanding of emotional intelligence in public service management. It highlights the need for more research on its applications and benefits.

    INTELIGÊNCIA EMOCIONAL COMO FERRAMENTA ESTRATÉGICA PARA A GESTÃO DE PESSOAS NO SERVIÇO PÚBLICO: MELHORIA DO CLIMA ORGANIZACIONAL E DA QUALIDADE DO ATENDIMENTO AO CIDADÃO · 2026 · DOI

  • A necessidade de uma ferramenta de rastreio eficaz e prática para o diabetes mellitus em farmácias comunitárias. A falta de estudos sobre a utilização da HbA1c em farmácias comunitárias.

    USO DA HEMOGLOBINA GLICADA (HBA1C) NO RASTREIO DO DIABETES MELLITUS EM FARMÁCIAS COMUNITÁRIAS: VANTAGENS, LIMITAÇÕES E PAPEL CLÍNICO DO FARMACÊUTICO · 2026 · DOI

  • Ainda não há um estudo de revisão sistemática que resuma os principais fatores associados à mortalidade em idosos por COVID-19 do ponto de vista global. Há uma necessidade de uma revisão sistemática para resumir os fatores associados à mortalidade em idosos por COVID-19.

    FATORES ASSOCIADOS À MORTALIDADE DE PESSOAS IDOSAS POR COVID-19: UMA REVISÃO SISTEMÁTICA COM DADOS MUNDIAIS · 2026 · DOI

  • The current approach to managing type 2 diabetes is insufficient. There is a gap between scientific knowledge and its application in the management and control of the disease.

    Enfermedad y padecimiento como objetos de estudio transdisciplinario para la prevención, tratamiento y control multidisciplinario de la diabetes tipo 2 · 2026 · DOI

  • Reality. Transdisciplinarity does not aim for the dominance of multiple disciplines; rather, it encourages the expansion of all disciplines to include those that traverse and transcend them”18.

    Enfermedad y padecimiento como objetos de estudio transdisciplinario para la prevención, tratamiento y control multidisciplinario de la diabetes tipo 2 · 2026 · DOI

  • The exact mechanisms of post-vaccination transverse myelitis remain unclear. There is a need for further studies to understand the underlying pathophysiology of post-vaccination transverse myelitis. The study highlights the importance of considering post-vaccination transverse myelitis as a potential complication of SARS-COV-2 vaccination.

    Transverse Myelitis following SARS-COV-2 vaccination: a case report · 2026 · DOI

  • Possible subdiagnosis and underreporting of cases, especially in regions with limited diagnostic capabilities. Concentration of registrations in large specialized centers and lack of data in some states.

    PREVALÊNCIA E ANÁLISE ESPACIAL DA COMUNICAÇÃO INTERVENTRICULAR NO BRASIL: UMA SÉRIE TEMPORAL DE CINCO ANOS · 2026 · DOI

  • Lack of studies on the temporal and spatial distribution of Communication Interventricular in Brazil. Limited understanding of the factors contributing to the increase in prevalence.

    PREVALÊNCIA E ANÁLISE ESPACIAL DA COMUNICAÇÃO INTERVENTRICULAR NO BRASIL: UMA SÉRIE TEMPORAL DE CINCO ANOS · 2026 · DOI

  • There is a lack of studies analyzing the panorama of hospitalizations for complicated diabetic foot treatment and amputations in patients with diabetes in the state of Piauí, Brazil. The study aims to fill this gap.

    TRATAMENTO DO PÉ DIABÉTICO COMPLICADO NO PIAUÍ: O QUE ESSE PANORAMA REVELA SOBRE O CUIDADO AO PACIENTE DIABÉTICO? · 2026 · DOI

  • There is a need for research on the impact of the pandemic on nutritional status. The existing literature has gaps in terms of comprehensive analysis. The study aims to fill this gap by providing a comprehensive analysis.

    REPERCUSSÕES DA PANDEMIA DE COVID-19 SOBRE O ESTADO NUTRICIONAL DA POPULAÇÃO MUNDIAL: UMA REVISÃO INTEGRATIVA DA LITERATURA · 2026 · DOI

  • The lack of institutionalization of local public policies under an international cooperative perspective. The lack of joint planning in public health and epidemiological surveillance.

    ENFRENTAMENTO DA COVID-19 EM REGIÃO TRANSFRONTEIRIÇA · 2026 · DOI

  • Further studies can use the SISAB data to investigate specific research questions, such as the impact of primary health care on health outcomes. Future research can apply the study's methodology to other countries with similar health information systems.

    The Rise of Brazil's Primary Care Digitalization: 12 Billion Records Across 27 Federative Units as a Foundation for Real-World Evidence and Scientific Democratization · 2026 · DOI

  • There is a lack of understanding of the clinical, epidemiological, and demographic profile of adolescents with covid-19. There is no clear evidence regarding the predominance of more symptomatic or asymptomatic cases in the adolescent population.

    Clinical, epidemiological, and demographic profile of adolescents with covid-19 in Divinópolis, central-west region of Minas Gerais · 2026 · DOI

  • Further research should examine the specific role of physiotherapy in the recovery of patients with SARA associated with COVID-19. Studies should investigate the effectiveness of different physiotherapeutic strategies in improving oxygenation and reducing complications in these patients.

    A IMPORTÂNCIA DA FISIOTERAPIA PARA PACIENTES EM USO DE VENTILAÇÃO MECÂNICA COM SARA GRAVE DECORRENTE A COVID - 19 · 2026 · DOI

  • There is a lack of studies analyzing temporal trends in cerebrovascular disease mortality in Brazil. There is a need to analyze changes in diagnostic profile and sociodemographic inequalities.

    CEREBROVASCULAR DISEASE MORTALITY IN BRAZIL: TEMPORAL TRENDS, CHANGES IN THE DIAGNOSTIC PROFILE, AND SOCIODEMOGRAPHIC INEQUALITIES, 2010–2024 · 2026 · DOI

Most-cited papers in Healthcare during COVID-19 Pandemic

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47 open questions have been extracted from the limitations and future-work passages of 375 Healthcare during COVID-19 Pandemic papers in our library. Each one below links back to the study that raised it, so you can read the original claim in context.

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