Open research questions in Hemispheric Asymmetry in Neuroscience
182 unresolved questions extracted from the limitations and future-work sections of 570 Hemispheric Asymmetry in Neuroscience papers in our library. Each links back to the study that raised it.
What the literature leaves open
The literature on lateral dominance is inconsistent, with some studies suggesting that left-handers are less lateralized than right-handers. The study seeks to address this inconsistency by using a range of performance and preference measures.
Left‐handers and right‐handers compared on performance and preference measures of lateral dominance · 1984 · DOIThe complexity of mental rotation and its role in spatial cognition. The need to understand the relationship between upward direction and horizontal directions. The challenge of designing intuitive and user-friendly interfaces for spatial tasks.
The paper identifies a gap in our understanding of how people interpret turns on a map using mental rotation. The study highlights the need for further research on the relationship between upward direction and horizontal directions.
The study identifies a gap in our understanding of manual asymmetry in infants. The study aims to address the discrepancy between the results obtained by Caplan and Kinsbourne and the present study.
The study faced challenges in developing a simple and easily communicable method of measurement. The research had to account for the lack of agreement on how to measure and define writing postures. The study had to control for environmental pressures.
Inverted and noninverted lefthanders compared on the basis of motor performance and measures related to the act of writing · 1983 · DOIThe study only measured a limited number of aspects of writing behavior. The research did not control for all possible environmental pressures. The sample size and population are not specified.
Inverted and noninverted lefthanders compared on the basis of motor performance and measures related to the act of writing · 1983 · DOIThe lack of a coherent framework for understanding the processes involved in interpreting and displaying emotion. The interaction of structural and cognitive factors in some studies of emotion.
The paper identifies a lack of understanding of how mood affects the 'Cerebral balance of power'. The paper notes that it is not known whether emotional events are apprehended independently of cognitive ones.
The paper identifies a need for effective methods to improve English skills in the classroom. The paper highlights the importance of communication and peer interaction in the learning process.
The effects of time-pressure on group decision-making accuracy and vertical structure are not well understood. Prior studies have found that time-pressure affects group decision-making, but the effects are not well understood. The study aims to fill the gap by examining the impact of time-pressure on group decision-making accuracy and vertical structure.
Some effects of time-pressure on vertical structure and decision-making accuracy in small groups · 1981 · DOIThe paper identifies a gap in the understanding of the neural basis of simultaneous and successive cognitive processes. The authors note that the relationship between these processes and brain divisions is not fully understood. The paper highlights the need for further research on the development of planning and coding processes in children.
The need to understand the relationship between handedness and developmental language problems. The importance of considering laterality in diagnostic examinations.
The factor stability of the EHI as a function of test-retest performance, age, and sex was not previously examined. The identification of items that load poorly on the handedness factor was not previously examined.
Factor stability of the Edinburgh Handedness Inventory as a function of test‐retest performance, age and sex · 1980 · DOIThe complexity of the brain and its functions makes it challenging to study. The lack of evidence for similar functional asymmetries in non-human vertebrates makes it difficult to draw conclusions.
Future research should investigate the causes of the systematic shift in lateral preference scores as a function of age. The study of laterality should consider individual differences and developmental factors.
The complexity of the brain and the difficulty of measuring its functions. The need to consider individual differences in cognitive abilities and behavioral functions. The importance of understanding the relationship between human brain organization and social organization.
The paper notes that there have been no functional studies that investigate lateralization of primates. The study of human brain organization is limited by the complexity of the brain and the difficulty of measuring its functions.
Traditional methods of teaching laterality are often ineffective. There is a need for a new approach to laterality training that incorporates movement, language, and sensory stimuli.
The challenge of understanding developmental changes in mental rotation skill. The difficulty of measuring individual differences in mental rotation ability. The need to develop educational programs that take into account individual differences in mental rotation ability.
The lack of study on possible developmental change in mental rotation skill beyond age 7 years. The need to study individual differences in mental rotation ability and their relation to academic success.
The dominance of left hemisphere functions in Western society and education. The need for more research on right brain functions in outdoor education. The challenge of designing outdoor education programs that stimulate right brain activity.
The paper suggests using portable EEG machines to measure children's mental activities during outdoor experiences. It proposes conducting new and nontraditional outdoor education research to determine the extent to which outdoor experiences facilitate right brain functioning and growth.
The study identifies a gap in our understanding of the effects of age on mental image rotation. Prior work has suggested a decline in the speed of response with advancing age, but the underlying mechanisms are not well understood.
Rotation of Mental Images by Young and Old College Students: The Effects of Familiarity · 1979 · DOIExisting reading programs may not be effective for nonreaders. There is a need for a new approach to reading instruction based on neurological development.
There was a gap in the understanding of cerebral dominance in ancient humans. There was a gap in the understanding of cerebral dominance in great apes.
Most-cited papers in Hemispheric Asymmetry in Neuroscience
- Lateral brain function, emotion, and conceptualization. · Psychological Bulletin · 1981 · 498 citations
- Human handedness: A meta-analysis. · Psychological Bulletin · 2020 · 439 citations
- Lateralization of functions in the vertebrate brain: A review · British Journal of Psychology · 1980 · 195 citations
- The joint development of hemispheric lateralization for words and faces. · Journal of Experimental Psychology General · 2012 · 153 citations
- Handedness in Chimpanzees (Pan troglodytes) Is Associated With Asymmetries of the Primary Motor Cortex but Not With Homologous Language Areas. · Behavioral Neuroscience · 2004 · 119 citations
- The Lateralisation of Emotion: A Critical Review · International Journal of Psychology · 1982 · 76 citations
- Factors Influencing the Prevalence and Handedness for Throwing in Captive Chimpanzees (Pan troglodytes). · Journal of comparative psychology · 2005 · 46 citations
- Use of Position and Feature Cues in Discrimination Learning by the Whiptail Lizard (Cnemidophorus inornatus). · Journal of comparative psychology · 2003 · 39 citations
- Sex differences in implicit motor imagery: Evidence from the hand laterality task · Acta Psychologica · 2020 · 32 citations
- Triadic balance in the brain: Seeking brain evidence for Heider’s structural balance theory · Social Networks · 2020 · 29 citations
Most recent work
- A mosaic of whole-body representations on the human precentral gyrus · Nature · 2026
- Neural mechanisms of handedness for precision drawing: hand-dependent engagement of cortical networks for bimanual control and tool use · bioRxiv · 2026
- Prediction of Handedness and Language Hemispheric Dominance Using Homotopic Connectivity of Language Areas · JoCN Forum · 2026
- CROSSED LATERALITY AND PERFORMANCE IN FENCING: AN ANALYSIS OF OCULAR DOMINANCE, HANDEDNESS, AND REACTION TIMES IN FENCERS · Revista Andaluza de Medicina del Deporte · 2026
- The enigma of persistent left-handedness in humans: A potential solution · medRxiv · 2026
- A tale of two ears: development of binaural auditory processing in the big brown bat · Journal of Comparative Physiology A · 2026
- Verbal versus Nonverbal Processing Leads to Generalized Hemispheric Laterality Effects that Span Multiple Networks · bioRxiv · 2026
- Structural Directional Brain Behavior Asymmetry Across Cortical and Non-Cortical Regions · bioRxiv · 2026
- The ‘Doginburgh Inventory’: from hands to paws in assessing canine motor laterality · Royal Society Open Science · 2026
- Navigating Change Between Proximity and Specialisation: Insights from Neuroscience · NEU · 2026
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