Open research questions in Adolescent and Pediatric Healthcare
279 gap statements mined from Adolescent and Pediatric Healthcare papers in our 7.9M-paper local library, which holds 1,753 papers on the topic — drawn mostly from each paper's own stated research gap, future-work, challenge and limitation notes, and its abstract. The ones listed below are a selection still marked open; each names the study that raised it, with a DOI link where the paper has one.
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What the literature leaves open
Limited discussion of reproductive health, insurance planning, and transition-related issues in current practices. Need for effective transition from pediatric to adult care for adolescents with CHD. Prior studies have demonstrated the importance of structured transition interventions, but more research is needed.
Impact of a Structured Transition Education Program on Transition Related Knowledge Among Adolescents with Congenital Heart Disease: A Single-Center Quality Improvement Study · 2026 · DOIThere is a lack of knowledge about the predictors and facilitators of positive transition experiences. Service boundaries often create care gaps, with some CAMHS terminating before young people can access AMHS.
Transitions from child to adult mental health care: the evidence-base for ESCAP guidance for clinicians · 2026 · DOIThe lack of interaction between systemic layers in transitional mental health care. The rigid age threshold of 18 years that constitutes an artificial divide in care. The siloed functioning between child and adult mental health services that creates a pronounced cultural and organisational gap.
Identifying needs and challenges in transitional mental health care: A scoping review on the perspectives of health and social care professionals · 2026 · DOIThe current transition process from CAP to follow-up care is often fragmented and poorly coordinated. There is a lack of understanding of the factors that are important and feasible for improving care transitions. The study aims to address this gap by exploring perspectives of clinicians, providers, parents, and youth.
Transitioning from child and adolescent psychiatry to follow-up care: a concept mapping study · 2026 · DOIThe lack of standardized educational approaches for clinicians in caring for children and young adults with complex medical needs. The limited didactic and clinical training in the provisions of services to individuals with intellectual and developmental disabilities. The need for more education and experiences in transitional care during training.
A Growing Need for a Standardized, System-Based Approach to the Transition of Children, Adolescence and Young Adults with Complex Medical Needs to Adult Care · 2026 · DOIDuring the latter half of the twentieth century, a growing understanding of adolescents' unique developmental, behavioral, and health care needs led clinicians and researchers to propose that traditional pediatric and adult medicine frameworks were insufficient to ensure the health and wellbeing of this population.
Germany’s health system offers financial protection and commits to adolescent participation, yet little is known about adolescents’ views of its performance.
Is the health system working for people? Comparison of adolescent and adult perspectives from the people´s voice survey in Germany · 2026 · DOIThe effectiveness of transition programs from pediatric to adult healthcare in adolescents with inflammatory bowel disease (IBD) is not clear, as prospective studies using validated outcome measures for transition are lacking.
Effectiveness of Transitional Care in Inflammatory Bowel Disease; Development, Validation, and Initial Outcomes of a Transition Success Score · 2024 · DOIAs the field of urology looks towards the future of transitional care, a number of areas should be prioritized. Most fundamentally, outcomes research pertaining to specific pathologies and clinical models is needed.
The study did not conduct a formal quality assessment due to the variety of study designs. The review is limited to the included studies and may not be generalizable to other populations.
Bridging Pediatric to Adult Care: A Scoping Review on Transitional Care for Individuals with Congenital Heart Disease Using Data Mining Techniques to Identify Key Topics · 2026 · DOIFuture studies should prioritize the development of standardized, evidence-based approaches to transitional care. Research should focus on the implementation and evaluation of transitional care programs. Studies should investigate the effectiveness of education-focused interventions in improving health outcomes for individuals with CHD.
Bridging Pediatric to Adult Care: A Scoping Review on Transitional Care for Individuals with Congenital Heart Disease Using Data Mining Techniques to Identify Key Topics · 2026 · DOIThe current guidelines for paediatrics in New Zealand are inconsistent and may not be serving the needs of young people. There is a lack of flexibility in the definition of age limits for paediatrics.
Limited research has explored parental beliefs, management practices, and factors contributing to delayed medical consultation in the Middle East, particularly in southern Iraq. There is a need to understand the factors associated with delayed medical consultation and to develop targeted interventions to promote earlier diagnosis and treatment of nocturnal enuresis.
Factors associated with delayed management of nocturnal enuresis: a cross-sectional study of parental perspectives · 2026 · DOIFurther study is needed to develop and implement effective psychological screening and support strategies for pediatric liver transplant recipients. Research is needed to identify the most effective structured transition pathways and sustained health education programs for these patients.
The current definition of success in pediatric liver transplantation is insufficient, focusing only on graft function and biochemical stability. The long-term outcomes of these patients are influenced by psychological and social factors, which are not adequately addressed in current care models.
Future work should evaluate the adapted Transition Readiness Assessment Questionnaire in community and international pediatric-onset multiple sclerosis samples. Future research should focus on developing strategies to support the transition to adult care in pediatric-onset multiple sclerosis.
Adaptation of the Transition Readiness Assessment Questionnaire for Pediatric-Onset Multiple Sclerosis: Protocol for a User-Centered Design Approach · 2026 · DOIIndividuals with neurologic impairment and technology assistance (NI+TA) have frequent interactions with the health care system, but little is known about their health outcomes following childhood.
Early Adulthood Outcomes Among Individuals With Neurologic Impairment and Technology Assistance · 2026 · DOILimited patient and public involvement (PPI) in both scale and geographical scope (UK only). Variable development of PPI across Europe.
European Society of Child and Adolescent Psychiatry (ESCAP) practical guidance for clinicians and mental health services regarding child to adult mental health service transitions and managed discharge at the service boundary · 2026 · DOIFurther explore how transitions can be shaped in partnership with youth and their families, and assess whether the Transition Navigation Model could be adapted to transitions from CAP to follow-up care within youth care services. Focus on implementation strategies to explore how recovery principles can be operationalized in practice and supported across organizational and professional boundaries.
Transitioning from child and adolescent psychiatry to follow-up care: a concept mapping study · 2026 · DOIAdolescent access to confidential care is codified by most states with age-specific laws; however, adolescent and guardian awareness of these laws are poorly understood.
HCT planning uptake remains low, with little known about HCT in the adolescent well child check (WCC) setting.
A Quality Improvement Initiative to Improve Health Care Transition Planning at Adolescent Well Visits · 2024 · DOIAddressing the complex needs of patients with epilepsy during the transition process. Evaluating the effectiveness of transition interventions in improving seizure outcomes.
Measuring transition success from paediatric to adult epilepsy services and its association with seizure outcomes: a UK retrospective cohort study · 2026 · DOIThe study had a small sample size (59 patients). The study was limited to patients in London, UK.
Measuring transition success from paediatric to adult epilepsy services and its association with seizure outcomes: a UK retrospective cohort study · 2026 · DOIThe study's sample sizes for patient and caregiver surveys may be limited due to the rarity of pediatric-onset multiple sclerosis. Generalizability to community-based settings or non-US health care contexts may be limited. The study's findings may not be generalizable to the broader pediatric-onset multiple sclerosis population.
Adaptation of the Transition Readiness Assessment Questionnaire for Pediatric-Onset Multiple Sclerosis: Protocol for a User-Centered Design Approach · 2026 · DOIFurther research on mental health service transitions is needed, - Investigation of the effectiveness of different transition models, - Examination of the impact of clinical guidance on transitional…
Transitions from child to adult mental health care: the evidence-base for ESCAP guidance for clinicians · 2026 · DOI
Most-cited papers in Adolescent and Pediatric Healthcare
- Our future: a Lancet commission on adolescent health and wellbeing · The Lancet · 2016 · 3,194 citations
- Adolescence: a foundation for future health · The Lancet · 2012 · 2,100 citations
- Children With Medical Complexity: An Emerging Population for Clinical and Research Initiatives · PEDIATRICS · 2011 · 1,184 citations
- A Consensus Statement on Health Care Transitions for Young Adults With Special Health Care Needs · PEDIATRICS · 2002 · 779 citations
- Supporting the Health Care Transition From Adolescence to Adulthood in the Medical Home · PEDIATRICS · 2018 · 774 citations
- Patterns and Costs of Health Care Use of Children With Medical Complexity · PEDIATRICS · 2012 · 589 citations
- Improving the transition between paediatric and adult healthcare: a systematic review · Archives of Disease in Childhood · 2011 · 557 citations
- Age Limit of Pediatrics · PEDIATRICS · 2017 · 520 citations
- Measuring the Transition Readiness of Youth with Special Healthcare Needs: Validation of the TRAQ—Transition Readiness Assessment Questionnaire · Journal of Pediatric Psychology · 2009 · 505 citations
- Pediatric Self-management: A Framework for Research, Practice, and Policy · PEDIATRICS · 2012 · 477 citations
Most recent work
- European Society for Paediatric Endocrinology (ESPE) and European Society of Endocrinology (ESE) joint clinical practice guidance for healthcare transition from paediatric to adult endocrine care · European Journal of Endocrinology · 2026
- Experiences of youth and caregivers waiting for mental health services in the UK: a qualitative study to inform policy and practice · European Child & Adolescent Psychiatry · 2026
- Redefining transition: Self-efficacy in urologic care · Journal of Pediatric Urology · 2026
- ACHD Care Wheel: Stakeholder- and Theory-Driven Framework to Improve Specialized Adult Congenital Heart Disease Care · medRxiv · 2026
- Transitioning Adolescents and Young Adults with Type 1 Diabetes Mellitus in Italy: A Scoping Review · Children · 2026
- European Society of Child and Adolescent Psychiatry (ESCAP) practical guidance for clinicians and mental health services regarding child to adult mental health service transitions and managed discharge at the service boundary · European Child & Adolescent Psychiatry · 2026
- Transitions from child to adult mental health care: the evidence-base for ESCAP guidance for clinicians · European Child & Adolescent Psychiatry · 2026
- A Europe-wide provider perspective of healthcare services for adolescent and young adult patients with haematological conditions: a survey from the Adolescent and Young Adult Taskforce of the European Hematology Association · EClinicalMedicine · 2026
- Healthcare transition readiness in an adolescent and young adult urologic population: The ADHERENT study · Journal of Pediatric Urology · 2026
- Grandfather Clauses and Medical Transition—Proposed CMS Rules Should Consider Exceptions · Archives of Pediatrics and Adolescent Medicine · 2026
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