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Open research questions in Adolescent and Pediatric Healthcare

152 unresolved questions extracted from the limitations and future-work sections of 1,048 Adolescent and Pediatric Healthcare papers in our library. Each links back to the study that raised it.

What the literature leaves open

  • The paper identifies the challenge of countries where ministries of health do not play a leading role, often having concomitant province-or state-level health care subsystems that issue differing public health recommendations. The paper also identifies the challenge of a lack of consensus on the terminology and definition of children and youth with special health care needs.

    Public health policies for children and youth with special health care needs in OECD member countries and Brazil: A scoping review · 2026 · DOI

  • The methodological choice may have led to underreporting of regional public policies of decentralized health care systems, - Childhood and adolescence being assumed as normally healthy periods in human life may have contributed to the lack of records, - A lack of consensus on the terminology and definition of CYSHCN may have contributed to the lack of records

    Public health policies for children and youth with special health care needs in OECD member countries and Brazil: A scoping review · 2026 · DOI

  • The study identified the challenge of discontinuity of care during the transition period. The lack of evidence-based interventions to improve transition was a significant challenge. The need for effective interventions to address the poor outcomes associated with poorly managed transitions was a major challenge.

    The effect of managed transition on the proportion of young people transitioning from CAMHS to AMHS: Analysis of the Milestone Cluster Randomised Clinical Trial · 2026 · DOI

  • The study identifies the challenge of investigating the long-term outcomes of CAMHS patients. It notes the complexity of analyzing the adult mental health outcomes of young people who attended CAMHS. The study highlights the need for further research to address the gaps in current knowledge on CAMHS patients' long-term outcomes.

    Adult psychiatric outcomes of young people who attended child and adolescent mental health services: a longitudinal total population study · 2025 · DOI

  • Research to alter the long-term trajectories of CAMHS patients, - Investigation of the incidence of multimorbidity across the diagnostic categories, - Examination of adult inpatient and outpatient service use for CAMHS users when stratified by sex

    Adult psychiatric outcomes of young people who attended child and adolescent mental health services: a longitudinal total population study · 2025 · DOI

  • However, most diagnoses in pregnant women have not been examined, and the role of familial confounding remains unknown.

    Familial confounding in the associations between maternal health and autism · 2025 · DOI

  • Evidence was limited regarding the long-term impact on mortality or transplant status.

    Transitioning care in cystic fibrosis: a comprehensive review of reviews of clinical and psychosocial outcomes · 2025 · DOI

  • However, there are no guidelines for measuring and valuing indirect costs in this population.

    Methodological considerations for estimating indirect costs in children and adolescents with chronic conditions: a scoping review · 2025 · DOI

  • While the study's design limits definitive conclusions on the program's impact on medication adherence, the observed improvements suggest that potential benefits warrant further investigation.

    The effectiveness of a transition programme based on the integrated theory of health behavior change in adolescents with chronic kidney disease: a quasi-experimental study · 2025 · DOI

  • One factor which may impact transition readiness among youth accessing CAMHS is the presence of a co-occurring physical health condition; however, this has not been previously examined.

    Transition Readiness Among Youth Accessing Mental Health Services With Physical Health Co‐Morbidities · 2024 · DOI

  • BACKGROUND: Transition readiness, or skills and preparation for navigating adult health care, is an important factor in the successful transition from child and adolescent mental health services (CAMHS) to adult care; however, predictors of transition readiness are not fully understood.

    Transition Readiness Among Youth Accessing Mental Health Services With Physical Health Co‐Morbidities · 2024 · DOI

  • Despite this, research into the economic cost for families of children with a rare disease is lacking.

    Caregiver-Reported Economic Impacts of Pediatric Rare Diseases—A Scoping Review · 2024 · DOI

  • However, our understanding of the disease burden, harm, and influencing factors of RA in this population remains insufficient.

    Global burden of rheumatoid arthritis among adolescents and young adults aged 10–24 years: A trend analysis study from 1990 to 2019 · 2024 · DOI

  • While there is evidence of some differences according to the underlying condition and gender, differences by measure and country are poorly understood.

    Health-related quality of life and self-reported health status in adolescents with chronic health conditions before transfer of care to adult health care: an international cohort study · 2024 · DOI

  • Management of multiple complex medical needs. Understanding and navigating the healthcare system. Reconciling their condition with their social and psychological development.

    Transitional urology: a comprehensive review of the transitional care process · 2026 · DOI

  • Outcomes-based studies for specific pathologies. Comparisons of different care implementation models. Creation and evaluation of training opportunities for non-urologic care team members.

    Transitional urology: a comprehensive review of the transitional care process · 2026 · DOI

  • Ensuring continuity of care during the transition from pediatric to adult services. Addressing the complex needs of patients with epilepsy during the transition process. Evaluating the effectiveness of transition interventions in improving seizure outcomes.

    Measuring transition success from paediatric to adult epilepsy services and its association with seizure outcomes: a UK retrospective cohort study · 2026 · DOI

  • The study had a small sample size (59 patients). The study was limited to patients in London, UK.

    Measuring transition success from paediatric to adult epilepsy services and its association with seizure outcomes: a UK retrospective cohort study · 2026 · DOI

  • The study did not conduct a formal quality assessment due to the variety of study designs. The review is limited to the included studies and may not be generalizable to other populations.

    Bridging Pediatric to Adult Care: A Scoping Review on Transitional Care for Individuals with Congenital Heart Disease Using Data Mining Techniques to Identify Key Topics · 2026 · DOI

  • Future studies should prioritize the development of standardized, evidence-based approaches to transitional care. Research should focus on the implementation and evaluation of transitional care programs. Studies should investigate the effectiveness of education-focused interventions in improving health outcomes for individuals with CHD.

    Bridging Pediatric to Adult Care: A Scoping Review on Transitional Care for Individuals with Congenital Heart Disease Using Data Mining Techniques to Identify Key Topics · 2026 · DOI

  • The current guidelines for paediatrics in New Zealand are inconsistent and may not be serving the needs of young people. There is a lack of flexibility in the definition of age limits for paediatrics.

    Eating disorders: do rigid age limits for paediatrics serve our young people? · 2026 · DOI

  • Limited research has explored parental beliefs, management practices, and factors contributing to delayed medical consultation in the Middle East, particularly in southern Iraq. There is a need to understand the factors associated with delayed medical consultation and to develop targeted interventions to promote earlier diagnosis and treatment of nocturnal enuresis.

    Factors associated with delayed management of nocturnal enuresis: a cross-sectional study of parental perspectives · 2026 · DOI

  • Further study is needed to develop and implement effective psychological screening and support strategies for pediatric liver transplant recipients. Research is needed to identify the most effective structured transition pathways and sustained health education programs for these patients.

    From graft survival to life: redefining success after pediatric liver transplantation · 2026 · DOI

  • The current definition of success in pediatric liver transplantation is insufficient, focusing only on graft function and biochemical stability. The long-term outcomes of these patients are influenced by psychological and social factors, which are not adequately addressed in current care models.

    From graft survival to life: redefining success after pediatric liver transplantation · 2026 · DOI

  • The study's sample sizes for patient and caregiver surveys may be limited due to the rarity of pediatric-onset multiple sclerosis. Generalizability to community-based settings or non-US health care contexts may be limited. The study's findings may not be generalizable to the broader pediatric-onset multiple sclerosis population.

    Adaptation of the Transition Readiness Assessment Questionnaire for Pediatric-Onset Multiple Sclerosis: Protocol for a User-Centered Design Approach · 2026 · DOI

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152 open questions have been extracted from the limitations and future-work passages of 1,048 Adolescent and Pediatric Healthcare papers in our library. Each one below links back to the study that raised it, so you can read the original claim in context.

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