Open research questions in Mobile Health and mHealth Applications
276 unresolved questions extracted from the limitations and future-work sections of 1,519 Mobile Health and mHealth Applications papers in our library. Each links back to the study that raised it.
What the literature leaves open
Small sample size, - Limited to Kenyan AGYW, - Limited generalizability to other populations
Co-design of a digital health intervention to provide pharmacy-based, person-centered contraceptive decision support for youth in Kenya · 2026 · DOIFurther testing of the Mara Divas App, - Expansion to other countries or populations, - Investigation of long-term effects of digital health contraceptive decision support
Co-design of a digital health intervention to provide pharmacy-based, person-centered contraceptive decision support for youth in Kenya · 2026 · DOIThe study identifies the challenge of evaluating the accuracy, reliability, and readability of AI chatbots in the context of gestational diabetes mellitus. The study highlights the challenge of ensuring the quality of health information on the internet. The study notes the challenge of developing AI chatbots that can provide clinically reasonable information and meet the needs of patients and healthcare providers.
Evaluation of validity, reliability, and readability of AI chatbots for gestational diabetes mellitus: a multi-model comparative study · 2026 · DOIThe accuracy, reliability, and readability of AI chatbots for gestational diabetes mellitus are unclear. There is a need for comprehensive evaluation of AI chatbots in this context. The study aims to address the gap in knowledge regarding the effectiveness of AI chatbots for gestational diabetes mellitus.
Evaluation of validity, reliability, and readability of AI chatbots for gestational diabetes mellitus: a multi-model comparative study · 2026 · DOIFurther studies could investigate the impact of addressing technical and usability barriers on user satisfaction and app adoption, - Research could explore the differences in barriers to app utilization among various demographic groups
Barriers to the utilization of the Sehaty mobile health application in Saudi Arabia: a cross-sectional survey of non-healthcare users · 2025 · DOIPrivacy and security issues from using public Wi-Fi and spaces remain a concern for librarians and healthcare professionals. Physical limitations to privacy can also be a concern when using community spaces for digital health access. Some individuals may be hesitant to use Wi-Fi in community spaces to access personal information due to privacy and confidentiality concerns.
Future community level program development should address concerns regarding security and privacy - Investigating patient perspectives on leveraging community Wi-Fi and spaces for digital health is needed
Consequently, current apps are insufficient to support health care professionals in their overall preventive work with adolescents.
Smartphone Apps for Preventing Adolescent Health Problems Among Health Care Professionals: Systematic Search and Quality Assessment · 2026 · DOIWhile evidence is accumulating that people increasingly use AI for health information, there remains limited evidence that such use translates into measurable improvement in health outcomes.
Evaluating the potential of conversational artificial intelligence for maternal and child health literacy in Pakistan · 2026 · DOIAbstract Background Digital health interventions are rapidly expanding in low- and middle-income countries (LMICs), yet little is known about how design and delivery components can be tailored to support engagement across diverse populations.
Moderators of design and delivery component effects on engagement with a digital parenting intervention: evidence from a factorial randomized trial in Tanzania · 2026 · DOIHeart failure (HF) involves cycles of remission and exacerbation, which are poorly characterized by static disease measures.
Consumer wearables have an understudied potential for daily monitoring of HF symptoms.
Despite the importance of digital health education, consensus on essential primary medical degree content is lacking.
Understanding the gap: a balanced multi-perspective approach to defining essential digital health competencies for medical graduates · 2025 · DOIBackground: Physical activity is essential in the prevention and management of type 2 diabetes mellitus (T2D), yet adherence to recommended activity levels remains insufficient.
Effectiveness of Wearable Technologies in Supporting Physical Activity and Metabolic Health in Adults with Type 2 Diabetes: A Systematic–Narrative Hybrid Review · 2025 · DOIWhile widely adopted, its dual role as both a support system and a source of burden remains underexplored.
From Peer Support to Program Supervision: Qualitative Insights on WhatsApp as Informal Digital Infrastructure for Community Health Workers and Public Health Officers in an Indian High-Priority Aspirational District · 2025 · DOIHowever, the adoption of these applications among the elderly population remains uncertain.
Attitudes of Elderly Population Toward Mobile Health Applications in Aseer Region, Saudi Arabia: A Cross-Sectional Study · 2025 · DOIHowever, little is known about users’ willingness to share their WAT data with healthcare providers.
User Experiences and Attitudes Toward Sharing Wearable Activity Tracker Data with Healthcare Providers: A Cross-Sectional Study · 2025 · DOIHowever, there remains limited evidence regarding the effectiveness of these mobile applications (apps).
Evaluation of Mobile Applications for Patients with Diabetes Mellitus: A Scoping Review · 2024 · DOIMETHODS: A validation study was conducted between August and December 2022 with 85 participants from two hospitals in Spain, who completed the pSUAPP questionnaire, comprising 27 Likert-like items across four dimensions: first contact, registration, features and overall experience, and 1 open question.
Validation of a Questionnaire to Assess the Usability of and User Experience with Mobile Health Applications · 2024 · DOIHowever, knowledge is lacking on the potential advantages and disadvantages of using this technology for WHP compared with nontechnical WHP programmes to support employers in their decision making and effective development of such an intervention.
Advantages and disadvantages of mobile applications for workplace health promotion: A scoping review · 2024 · DOIFew studies have explored how adult children really feel about engaging in the glucose management of their older parents with type 2 diabetes mellitus (T2DM) through mobile apps.
Role perceptions and experiences of adult children in remote glucose management for older parents with type 2 diabetes mellitus: a qualitative study · 2024 · DOIConclusions and Relevance: In this randomized clinical trial testing an adaptive intervention, the provision of coaching for individuals with suboptimal response improved WL and was cost-effective; further testing in clinical settings (eg, health care systems) is warranted.
An Adaptive Telephone Coaching Intervention for Patients in an Online Weight Loss Program · 2024 · DOIThe large-scale adoption of IoT-enabled geriatric care remains limited, - The integration of IoT systems into clinical practice requires careful consideration of sociotechnical factors
Bridging the Socio-Technical Gap: A 2024–2025 Review of Integrated IoT Solutions for Geriatric Care · 2026 · DOIHowever, cross-therapeutic reviews examining sensor-based DHTs as outcome measurement tools rather than interventions in recent pharmaceutical and device trials are lacking, limiting understanding of practical implementation and utility in COA development for use in clinical trials.
Sensor-based digital health technologies to capture endpoints in recent clinical trials: a scoping review · 2026 · DOIMost fitness apps offer general plans that don’t meet the specific needs of users. General plans overlook personal differences like body type, lifestyle, and fitness goals.
Most-cited papers in Mobile Health and mHealth Applications
- Diary Methods: Capturing Life as it is Lived · Annual Review of Psychology · 2002 · 2,764 citations
- Just-in-Time Adaptive Interventions (JITAIs) in Mobile Health: Key Components and Design Principles for Ongoing Health Behavior Support · Annals of Behavioral Medicine · 2016 · 1,902 citations
- Behavior Change Interventions Delivered by Mobile Telephone Short-Message Service · American Journal of Preventive Medicine · 2009 · 991 citations
- Use of the Internet and E-mail for Health Care Information · JAMA · 2003 · 880 citations
- Mobile Health Technology Evaluation · American Journal of Preventive Medicine · 2013 · 823 citations
- Annual Research Review: Digital health interventions for children and young people with mental health problems – a systematic and meta‐review · Journal of Child Psychology and Psychiatry · 2016 · 770 citations
- Mobile Text Messaging for Health: A Systematic Review of Reviews · Annual Review of Public Health · 2015 · 753 citations
- mHealth for mental health: Integrating smartphone technology in behavioral healthcare. · Professional Psychology Research and Practice · 2011 · 684 citations
- Characteristics of online and offline health information seekers and factors that discriminate between them · Social Science & Medicine · 2004 · 644 citations
- The digitally engaged patient: Self-monitoring and self-care in the digital health era · Social Theory & Health · 2013 · 624 citations
Most recent work
- Evaluation of validity, reliability, and readability of AI chatbots for gestational diabetes mellitus: a multi-model comparative study · Frontiers in Public Health · 2026
- Acceptance and use of digital health technologies among physiotherapists in Germany: a web-based cross-sectional survey · BMC Health Services Research · 2026
- Co-designing the future: End-user involvement in digital interventions · npj Digital Medicine · 2026
- Health care access from the rural perspective: A narrative review · The Journal of Rural Health · 2026
- Impact of a Smartwatch Hypertension Notification Feature for Population Screening · JAMA · 2026
- Remote monitoring of heart failure exacerbations using a smartwatch · Nature Medicine · 2026
- The All of Us Research Program’s wearables dataset · Nature Medicine · 2026
- eHealth competency needs in the Mekong border region: a GLMM analysis of primary care personnel in Nong Khai, Thailand · BMC Health Services Research · 2026
- A comprehensive public health approach is needed to study the impact of digital technology on health · BMJ · 2026
- Digital health system integration in Ghana: a scoping review of governance arrangements, interoperability aspirations, and regulatory gaps · BMC Health Services Research · 2026
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