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Open research questions in Central Venous Catheters and Hemodialysis

25 unresolved questions extracted from the limitations and future-work sections of 357 Central Venous Catheters and Hemodialysis papers in our library. Each links back to the study that raised it.

What the literature leaves open

  • While findings are limited by the sample size and the single-country setting, they highlight the potential clinical and organizational value of structured VAT models, particularly in high-complexity areas such as ICUs and oncology units.

    Management and vessel health in intensive care units and oncology settings led by vascular access team nurse specialists: a brief report · 2026 · DOI

  •  A similar study can be conducted with large sample size for better utilization.  A similar study can be conducted with control group to correlate the findings  A similar study can be conducted by using either true or quasi experimental design.  A comparative study can be conducted with other non-pharmacological interventions to determine in pain management during AV fistula puncturing among hemodialysis patients. effectiveness their  A survey can be done to assess the present interventions used by nurses to minimize level of pain during AV fistula puncturing. Conflict of Interest: The authors certify that they have no involvement in any organization or entity with any financial or non-financial interest in the subject matter or materials discussed in this paper.

    A Study To Determine The Effectiveness Of Cryotherapy On Pain Management During Arterio Venous Fistula (AVF) Puncturing Among Patients Undergoing Hemodialysis In P.E.S Hospital, Kuppam, Chittoor District, A.P · 2026 · DOI

  • reported male sex as a poten- tial risk factor in one study within a large meta-analysis, overall evidence remains inconsistent [15], and our findings suggest that sex is unlikely to be a major determinant of pathogen class in pediatric CRI.

    Pathogen-specific clinical and inflammatory phenotypes in pediatric catheter-related infections · 2026 · DOI

  • Advancement of long femorally inserted central catheters (FICCs), particularly 4–5 Fr, 55 cm devices introduced via the superficial femoral vein at mid-thigh, may be limited by the presence of venous valves, bifurcations, or inadvertent diversion into collateral pathways such as the ascending lumbar vein.

    A modified guidewire-assisted technique to facilitate advancement of long femoral central catheters into the inferior vena cava and prevent malposition · 2026 · DOI

  • Conclusion: Computed tomography angiography effectively assesses AVF stenosis and guides interventions, though its long-term prognostic value warrants further study.

    The value of computed tomography angiography in evaluating autogenous arteriovenous fistula dysfunction in haemodialysis patients · 2026 · DOI

  • Biomechanical analysis and material testing of the fractured segment were not performed, preventing a quantitative assessment of stress from compression and fatigue. Long-term data on the efficacy of posture modification are also lacking. Future studies should explore the relationship between obesity, sleeping positions, and catheter failure. Improved monitoring protocols are needed for high-risk patients, especially those who are obese or have specific positional needs.

    Implantable venous access port catheter fracture in a severely obese lung cancer patient undergoing chemotherapy: a case report · 2026 · DOI

  • Future research is recommended to involve larger multicenter cohorts with longer follow-up periods and to explore additional biological and hemodynamic factors, including vessel wall characteristics and inflammatory markers, which may better explain restenosis and long-term access failure.

    The Effect of Cephalic Arch Stenosis Location on Angioplasty Success and Patency at 3 and 6 Months in Patients with Brachiocephalic Fistula · 2026 · DOI

  • While findings are limited by minor variations in data col- lection methods, and outcomes of interest between the two included RCTs, the large sample with which tool discrimi- nation and responsiveness could be analysed presented a significant strength to the methods and subsequent findings. For both included RCTs (conducted exclusively in Austra- lia), a suitably trained Research Nurse was responsible for PROM and PREM administration, therefore findings may not be replicated among hospitals in which PROM and PREM collection is dispersed hospital or health services wide. While there was significant attrition between EQ5D- 5L T0 (baseline) and T1 (study completion, PICC removal), general homogeneity between patient demographics and rates of outcomes of interest between T0 and T1 suggests the impact of this attrition was minimal. Finally, the impact of various diagnosis, and treatment factors upon HRQoL (for example admitted [inpatient] days) may have been underestimated due to the inherent focus on factors related to the PICC specifically.

    Performance of EQ5D-5L and AHPEQS for measuring outcomes and experiences of patients with peripherally inserted central catheters: a secondary analysis · 2026 · DOI

  • BACKGROUND: Data on the feasibility of an ultrasound‑guided venous access (USGVA) for catheter ablation (CA) and electrophysiological studies (EPS) in large cohorts are scarce.

    Ultrasound‑guided venous access facilitated by the Valsalva maneuver during invasive electrophysiological procedures · 2020 · DOI

  • However, the study show that the majority of students have insufficient knowledge of the procedures accompanying insertion of a catheter, signs that indicate correct functioning of CVC, frequency of flushing a catheter when it is not in use and the reasons for introducing an implanted CVC.

    Knowledge of nursing students about central venous catheters · 2012 · DOI

  • Conclusions: Preoperative volume status appears to be an underrecognized and potentially modifiable determinant of vascular access conditions.

    Preoperative volume status in vascular access creation: A despised influence? · 2026 · DOI

  • Therefore, prospective, multicenter studies with appropriate adjust- ment for these variables are warranted to better define the optimal vascular access strategy in this high-risk population.

    Peripherally inserted central venous catheters for remission induction chemotherapy phase of acute leukemia: a single center experience in severely thrombocytopenic patients · 2026 · DOI

  • Although the factors contributing to catheter dysfunction are well recognized, the ultrastructural changes of fibrin sheaths in long-term indwelling catheters have not been systematically documented in the literature.

    Beyond the 10-year barrier: ultrastructural insights into long-term tunneled catheter function from calcified specimens—a report on 4 cases · 2026 · DOI

  • Dissection of a superficialized brachial artery (SBA) used for dialysis access has rarely been described, and its management is not well established.

    Dissection in a superficialized brachial artery for hemodialysis access: a case report · 2026 · DOI

  • Abstract Purpose Proximal reflux of liquid embolic agents remains a primary safety concern during endovascular embolization, yet the quantitative relationships governing reflux mechanics are poorly characterized.

    Why catheter size matters more than viscosity in ethylene–vinyl alcohol copolymer reflux: an analytical study · 2026 · DOI

  • Limited by the evidence quality, more studies from different area and populations with rigorous design are needed to investigate the role of heparin versus normal saline for the care of peripheral intravenous catheters in pediatrics.

    Heparin versus normal saline for the care of peripheral intravenous catheters in pediatrics: a meta-analysis of randomized controlled trials · 2024 · DOI

  • The number of introduced venous access catheters remains insufficient to meet the needs in the Czech Republic, which necessitates increased awareness and possibilities for safe drug administration.

    Indications for venous access in oncology – recommendations of national professional societies and current state in the Czech Republic · 2021 · DOI

  • Based on own observations and despite the lack of validation of ultrasound imaging in the assessment of central catheters, we believe that this method is highly promising and can be recommended for the assessment of thrombotic complications in pediatric patients with central venous catheters.

    Zastosowanie ultrasonografi i w ocenie powikłań zakrzepowych u dzieci z centralnymi, tunelizowanymi cewnikami dożylnymi · 2013 · DOI

  • Home infusion therapy is the fastest growing segment of home care, yet little is known about the utilization of various venous access devices in the home.

    Venous Access Device Utilization in Home Care Settings · 1994 · DOI

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25 open questions have been extracted from the limitations and future-work passages of 357 Central Venous Catheters and Hemodialysis papers in our library. Each one below links back to the study that raised it, so you can read the original claim in context.

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