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Open research questions in Dental Anxiety and Anesthesia Techniques

336 gap statements mined from Dental Anxiety and Anesthesia Techniques papers in our 7.9M-paper local library, which holds 2,656 papers on the topic — drawn mostly from each paper's own stated research gap, future-work, challenge and limitation notes, and its abstract. The ones listed below are a selection still marked open; each names the study that raised it, with a DOI link where the paper has one.

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What the literature leaves open

  • The study aims to address this gap by systematically comparing anaesthetic outcomes. The study investigates the effect of buffering on the depth of anaesthesia, onset time, and pain perception.

    Efficacy of Buffered vs. Non–buffered 4% Articaine Local Anaesthetic Solution in Abscessed Tooth: An Interventional Comparative Double Blind Clinical Study · 2026 · DOI

  • There is a need for effective methods to prevent radial artery spasm and pain in patients undergoing trans-radial angiography. Current methods have limitations and complications.

    Preparing and evaluating the effectiveness of topical cerosome of menthol on radial spasm and pain in patients with trans-radial angiography: a randomized, triple-blind, parallel placebo-controlled clinical trial · 2026 · DOI

  • One challenge is the potential for arch-or order-related bias due to fixed device allocation. Another challenge is the limited sample size of the study. The study also faced the challenge of quantifying the contribution of periodontal condition and baseline psychological factors.

    Pain Perception and Psychoemotional Responses Across Different Scaling Technologies: A Comparative Pilot Clinical Study · 2025 · DOI

  • The gap in current research is the lack of understanding of how ultrasonic technology influences patient-reported pain and psychoemotional status. The study aims to fill this gap by providing a comparative pilot clinical study.

    Pain Perception and Psychoemotional Responses Across Different Scaling Technologies: A Comparative Pilot Clinical Study · 2025 · DOI

  • The limited and heterogeneous nature of the available literature on CCIA in children. The need for more comprehensive, high-quality research to establish firm clinical conclusions. The lack of high-quality comparative studies precludes quantitative synthesis.

    Comparison of Intraosseous and Conventional Dental Anesthesia in Children—A Scoping Review · 2025 · DOI

  • The study aims to address this gap by assessing the effectiveness of Virtual Reality Exposure Therapy.

    Managing Dentophobia in the Digital Age: The Role of Internet Addiction and Virtual Reality Exposure Therapy · 2025 · DOI

  • The evolution of physiological responses over the course of dental treatment is not well understood. There is a lack of real-time assessment of patients' physiological and subjective responses during dental treatment. The gap in understanding the temporal characteristics of physiological responses during dental treatment is highlighted.

    Real-Time Subjective and Physiological Responses During Dental Treatment: Temporal Characteristics of Skin Temperature and Electrodermal Activity · 2026 · DOI

  • The decline in the prevalence of high DA observed in Finnish national studies among women between 2000 and 2011 and among men between 2000 and 2023 is in concordance with the limited evidence reported for adult populations.

    Level of Dental Anxiety and Its Role Among Barriers to Habitual Use of Oral Health Care in Adult Finns · 2026 · DOI

  • There is a need to evaluate the effectiveness of new approaches to reducing dental anxiety. The use of VR technology is a relatively new approach to reducing dental anxiety.

    Effectiveness of visual distraction tool in lowering the pain perception and anxiety levels of <span style="font-size: 1rem;">patients during surgical removal of impacted teeth: A randomized controlled study</span> · 2026 · DOI

  • Given the limited literature on student perspectives in OMFS and the single-center focus of this study, future research involving diverse dental faculties globally is needed to provide a broader perspective.

    Evaluation of the Perspectives of 5th-Year Dental Students on Oral and Maxillofacial Surgery Clinical Practice · 2026 · DOI

  • The study highlights the need for further research on the prevalence and etiology of supernumerary teeth.

    Exodontia de dente supranumerário na mandíbula em paciente com transtorno de ansiedade generalizado: relato de caso · 2026 · DOI

  • The relationship between orthognathic surgery and psychological factors is not fully understood. There is a need for more research on the factors that influence patient satisfaction with orthognathic surgery. There is a need for more research on the complications and risks associated with orthognathic surgery.

    Treatment outcomes, symptoms of anxiety and depression, and satisfaction with life after orthognathic surgery · 2026 · DOI

  • The long-term outcomes of VR-based interventions beyond the immediate procedure have not been adequately studied. And perhaps most practically, there is still no consensus on a standardized anxiety screening protocol for routine dental practice, a gap that limits the translation of research findings into clinical reality.

    Fear in the Dental Chair: A Narrative Review of Dental Anxiety Prevalence, Oral Health Consequences and the Evidence Behind Behavioral, Pharmacological and Sedation-Based Interventions · 2026 · DOI

  • Further studies can investigate the use of intraoral scanning in different populations. The effects of intraoral scanning on treatment outcomes can be evaluated.

    Comparison of Patient Comfort and Preference between Conventional and Digital Impressions in Adolescents with Multibracket Appliance : A Randomised Crossover Study · 2026 · DOI

  • There is a need to compare patient comfort and preference between conventional and digital impressions in adolescents with multibracket appliances. Previous studies have focused on pediatric populations without multibracket appliances.

    Comparison of Patient Comfort and Preference between Conventional and Digital Impressions in Adolescents with Multibracket Appliance : A Randomised Crossover Study · 2026 · DOI

  • There is a lack of a comprehensive competency framework for specialist nurses in outpatient dental sedation and anesthesia. The safety of dental sedation in Non-Operating Room Anesthesia settings remains a significant concern.

    Development of a multidisciplinary competency framework for specialist nurses in outpatient dental sedation and anesthesia: a mixed-methods Delphi and AHP study · 2026 · DOI

  • The literature is limited and predominantly focused on autism spectrum disorder. The review only includes studies published from 2020 to 2026. The study does not provide a comprehensive overview of all non-pharmacological chairside management strategies.

    Adapting the Chairside: Pediatric Dental Management for Children with Neurodevelopmental Disorders – A Scoping Review · 2026 · DOI

  • The literature is limited and predominantly focused on autism spectrum disorder. There is a need for further research on other neurodevelopmental disorder profiles. The review highlights a gap in the understanding of effective non-pharmacological chairside management strategies.

    Adapting the Chairside: Pediatric Dental Management for Children with Neurodevelopmental Disorders – A Scoping Review · 2026 · DOI

  • Future studies with larger sample sizes and stratification based on infection severity may provide additional insights, - Studies to address the gap by systematically comparing anaesthetic outcomes between buffered and non-buffered 4% articaine…

    Efficacy of Buffered vs. Non–buffered 4% Articaine Local Anaesthetic Solution in Abscessed Tooth: An Interventional Comparative Double Blind Clinical Study · 2026 · DOI

  • Small sample size of 50 children - Limited to children with no systemic diseases, intellectual disability, and psychiatric disorders - Limited to children with no known allergy…

    Comparative evaluation of sensory-adapted dental environment and conventional dental environment on dental anxiety and behaviour in children: a randomized controlled trial · 2026 · DOI

  • Further studies with larger sample sizes are needed - Studies comparing the effectiveness of SADE and CDE in different age groups are needed - Research on the long-term effects of SADE and CDE on dental anxiety…

    Comparative evaluation of sensory-adapted dental environment and conventional dental environment on dental anxiety and behaviour in children: a randomized controlled trial · 2026 · DOI

  • Examining whether quantitative measures derived from continuous physiological signals adequately represent the temporal course of the underlying physiological responses, - Investigating the temporal characteristics of EDA responses during dental treatment in a larger…

    Real-Time Subjective and Physiological Responses During Dental Treatment: Temporal Characteristics of Skin Temperature and Electrodermal Activity · 2026 · DOI

  • Small sample size of 31 patients, - Technical failure in one patient, - Limited to a specific population and setting, - No long-term follow-up, - No comparison to other anesthetic…

    An Updated Digital Approach to Regional Anesthesia: A Pilot Study on Computer-Guided Maxillary Nerve Block via the Greater Palatine Canal · 2025 · DOI

  • Further studies with larger sample sizes, - Comparison to other anesthetic techniques, - Investigation of long-term effects, - Exploration of the GPC approach in different populations…

    An Updated Digital Approach to Regional Anesthesia: A Pilot Study on Computer-Guided Maxillary Nerve Block via the Greater Palatine Canal · 2025 · DOI

  • More comprehensive, high-quality research is needed to establish firm clinical conclusions, - Future studies should assess the anesthetic effects and duration, - Future studies should use specific tools for determining the efficacy…

    Comparison of Intraosseous and Conventional Dental Anesthesia in Children—A Scoping Review · 2025 · DOI

Most-cited papers in Dental Anxiety and Anesthesia Techniques

Most recent work

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Open questions raised by papers listed on this page include: (1) There is a need for effective methods to prevent radial artery spasm and pain in patients undergoing trans-radial angiography (“Preparing and evaluating the effectiveness of topical cerosome of menthol on…”, 2026); (2) The evolution of physiological responses over the course of dental treatment is not well understood (“Real-Time Subjective and Physiological Responses During Dental Treatment:…”, 2026); (3) There is a need to evaluate the effectiveness of new approaches to reducing dental anxiety (“Effectiveness of visual distraction tool in lowering the pain perception and…”, 2026); (4) The relationship between orthognathic surgery and psychological factors is not fully understood (“Treatment outcomes, symptoms of anxiety and depression, and satisfaction with…”, 2026); (5) And perhaps most practically, there is still no consensus on a standardized anxiety screening protocol for routine dental practice, a gap that limits the translation of research findings into clinical reality (“Fear in the Dental Chair: A Narrative Review of Dental Anxiety Prevalence, Oral…”, 2026). 336 gap statements have been mined from Dental Anxiety and Anesthesia Techniques papers in our 7.9M-paper local library, which holds 2,656 papers on the topic; the gaps come from whichever of those papers state one. They are mostly the research gaps the authors state and the papers' abstracts, plus future-work, limitations and challenges passages. The ones listed below are a selection still marked open; each names the study that raised it, with a DOI link where the paper has one, so you can read the original claim in context.

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