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Open research questions in Dysphagia Assessment and Management

599 gap statements mined from Dysphagia Assessment and Management papers in our 7.9M-paper local library, which holds 2,353 papers on the topic — drawn mostly from each paper's own stated research gap, future-work, challenge and limitation notes, and its abstract. The ones listed below are a selection still marked open; each names the study that raised it, with a DOI link where the paper has one.

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What the literature leaves open

  • The study needs to develop a reliable index for discriminating MSA from PD based on swallowing-breathing coordination. The study must account for the variability in disease duration and severity among MSA patients.

    Abnormal swallowing–breathing coordination is an electrokinesiographic feature of dysphagia in multiple system atrophy: a comparative study with Parkinson’s disease · 2026 · DOI

  • The longitudinal heterogeneity of swallowing recovery in ICU patients with post-extubation dysphagia is not well understood. Prior studies have not characterized distinct recovery trajectories or identified clinical predictors associated with each pattern.

    Recovery Trajectories and Predictors of Post-Extubation Dysphagia in Intensive Care Unit Patients Following Orotracheal Intubation: A Longitudinal Study · 2026 · DOI

  • The study identifies the challenge of measuring tongue pressure accurately, citing the need for further validation of the five-point tongue pressure sensor. The study identifies the challenge of analyzing correlations between tongue pressure and swallowing physiology and aspiration in PSD.

    Tongue pressure in patients with post-stroke dysphagia · 2026 · DOI

  • Prospective validation of the five-point tongue pressure sensor is needed. Further research on the clinical application of site-specific tongue pressure measurement is required.

    Tongue pressure in patients with post-stroke dysphagia · 2026 · DOI

  • The effects of music-based exercise on oral function in patients with maxillofacial defects remain unclear. There is a need for innovative therapeutic interventions to improve oral function in these patients.

    Impact of a music exercise on oral function in patients with maxillofacial defects: a pilot randomized controlled trial · 2026 · DOI

  • Dysphagia can lead to malnutrition, aspiration pneumonia, involuntary weight loss, functional decline, hospital readmission, and even higher mortality. The effectiveness of specific interventions in this population remains undocumented. Instrumental methods (FEES/VFS) were rarely accessible.

    Clinical Practice Patterns of Assessment and Interventions for Elderly Patients with a Hip Fracture Who Are at Risk of Dysphagia—A Survey · 2025 · DOI

  • To address the challenges of limited data and complex multimodal signals, we propose a large language model (LLM)-based framework for dysphagia screening.

    LLM-Powered Dysphagia Screening With Multimodal Physiological Signal Analysis and Medically Informed Prompts · 2026 · DOI

  • Traditional diagnostic techniques, such as bedside screening and videofluoroscopic swallowing studies, are limited by accessibility, reliability, and invasiveness.

    LLM-Powered Dysphagia Screening With Multimodal Physiological Signal Analysis and Medically Informed Prompts · 2026 · DOI

  • Future research should focus on developing automated detection algorithms and multimodal datasets that combine physiological measurements and swallowing imaging to objectively link sensor-derived features to physiological swallowing events.

    Effects of aging and bolus characteristics on laryngeal movement during oropharyngeal swallowing · 2026 · DOI

  • Aging is a risk factor for diminished laryngeal sensation, dysphagia, and aspiration events; however, the mechanisms underlying age-related swallow dysfunction are not well understood.

    Effects of Aging on Superior Laryngeal Sensory and Motor Function in a Rat Model · 2026 · DOI

  • Swallowing biomechanics in primates and other mammals is poorly understood, and the effect of hyoid descent on swallowing biomechanics lacks experimental interrogation.

    Primate Swallowing Is Powered by Both Rotation and Contraction of Suprahyoid Muscles · 2026 · DOI

  • Dysphagia in geriatric patients is associated with adverse outcomes, but often remains under-recognized in routine care.

    Dysphagia as a geriatric syndrome: nationwide outcomes from the GEMIDAS registry · 2026 · DOI

  • The appropriate timing of gastrostomy tube placement in patients with acute ischemic stroke who have dysphagia remains unclear.

    Factors and outcomes associated with early and deferred gastrostomy tube placement in acute ischemic stroke patients in the United States · 2026 · DOI

  • Further validation of the PRESS score in prospective cohorts is warranted.

    External validation of the predictive swallow score for dysphagia in stroke patients · 2026 · DOI

  • Despite electroacupuncture (EA) being widely used to treat dysphagia, its effectiveness and underlying mechanism of action have not been thoroughly examined.

    Electroacupuncture treatment for post-stroke oropharyngeal dysphagia: a randomized controlled trial · 2025 · DOI

  • However, the therapeutic effect of acupuncture alone on post-stroke dysphagia remains unclear.

    Therapeutic effect of acupuncture on post-stroke dysphagia: A multicenter, randomized controlled trial · 2025 · DOI

  • Nasogastric tube feeding is commonly used for enteral nutrition in individuals with advanced dementia with feeding difficulties, but its impact on survival and pneumonia risk compared to careful hand feeding remains controversial.

    Comparison of survival and pneumonia risk in advanced dementia patients on nasogastric tube feeding versus careful hand feeding · 2025 · DOI

  • However, nurses, especially those in low- and middle-income countries, generally lack the ability to manage PSD, and the current state of Chinese public hospital registered nurses' relevant clinical practice remains unclear.

    The Practices of Public Hospital Registered Nurses Regarding Post-Stroke Dysphagia, in China · 2025 · DOI

  • Information about dysarthria and dysphagia in mitochondrial diseases (MD) is scarce.

    Dysarthria and dysphagia in patients with mitochondrial diseases · 2024 · DOI

  • Poststroke dysphagia is common and adversely affects patient outcomes, yet no standardised tool exists to assess nursing management capacity in this area.

    Development and Psychometric Evaluation of the Nursing Management Capacity Scale for Poststroke Dysphagia Based on the Donabedian Model · 2026 · DOI

  • Dysphagia is a common and often underrecognized symptom in patients with Parkinson's disease (PD) that is frequently overlooked during hospitalization.

    Consensus expert recommendations for management of dysphagia during hospital admission in Parkinson's disease · 2026 · DOI

  • Oropharyngeal dysphagia is a major yet underrecognized health problem in older persons.

    Progress in dysphagia management in older patients · 2024 · DOI

  • Despite widespread use of high flow nasal cannula (HFNC) for respiratory support, the effect of HFNC on swallowing physiology is poorly understood.

    Assessment of Swallowing Function in Healthy Adults While Using High‐Flow Nasal Cannula · 2024 · DOI

  • The study was retrospective, - The sample size was limited, - The study only included patients with the parkinsonian and cerebellar variants…

    Abnormal swallowing–breathing coordination is an electrokinesiographic feature of dysphagia in multiple system atrophy: a comparative study with Parkinson’s disease · 2026 · DOI

  • Future research on patient outcomes and the effectiveness of specific interventions in this population, - Targeted research on patient outcomes and effective interventions in hip fracture…

    Clinical Practice Patterns of Assessment and Interventions for Elderly Patients with a Hip Fracture Who Are at Risk of Dysphagia—A Survey · 2025 · DOI

Most-cited papers in Dysphagia Assessment and Management

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Open questions raised by papers listed on this page include: (1) The longitudinal heterogeneity of swallowing recovery in ICU patients with post-extubation dysphagia is not well understood (“Recovery Trajectories and Predictors of Post-Extubation Dysphagia in Intensive…”, 2026); (2) Prospective validation of the five-point tongue pressure sensor is needed (“Tongue pressure in patients with post-stroke dysphagia”, 2026); (3) The effects of music-based exercise on oral function in patients with maxillofacial defects remain unclear (“Impact of a music exercise on oral function in patients with maxillofacial…”, 2026); (4) Future research should focus on developing automated detection algorithms and multimodal datasets that combine physiological measurements and swallowing imaging to objectively link sensor-derived features to physiological swallowing events (“Effects of aging and bolus characteristics on laryngeal movement during…”, 2026); (5) Aging is a risk factor for diminished laryngeal sensation, dysphagia, and aspiration events; however, the mechanisms underlying age-related swallow dysfunction are not well understood (“Effects of Aging on Superior Laryngeal Sensory and Motor Function in a Rat Model”, 2026). 599 gap statements have been mined from Dysphagia Assessment and Management papers in our 7.9M-paper local library, which holds 2,353 papers on the topic; the gaps come from whichever of those papers state one. They are mostly the research gaps the authors state and the papers' abstracts, plus future-work, limitations and challenges passages. The ones listed below are a selection still marked open; each names the study that raised it, with a DOI link where the paper has one, so you can read the original claim in context.

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