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Open research questions in Electronic Health Records Systems

571 gap statements mined from Electronic Health Records Systems papers in our 7.9M-paper local library, which holds 3,282 papers on the topic — drawn mostly from each paper's own stated research gap, future-work, challenge and limitation notes, and its abstract. The ones listed below are a selection still marked open; each names the study that raised it, with a DOI link where the paper has one.

Choosing where to publish on Electronic Health Records Systems? See the ranked Medicine journals.

What the literature leaves open

  • Fragmented systems and repeated transcription limit the implementation of decentralized clinical trials. Incomplete auditability and lack of data integrity, traceability, and security are major challenges in conventional electronic data capture centric workflows. Integrating heterogeneous systems and supporting cross-system data exchange and coordination in decentralized clinical trials is a technical challenge.

    A certifiable evidence-chain digital platform supporting decentralized clinical trials: architecture and real-world evaluation · 2026 · DOI

  • Lack of standardized documentation for ventral hernia repair operative reports. Variable quality of narrative operative notes. Need for improved documentation protocols to enhance patient care and clinical decisions.

    Quality review of ventral hernia repair operative reports · 2026 · DOI

  • The variation in FCP service delivery and the need for data collection and governance. The challenge of FCPs practicing at an advanced level in the clinical pillar of practice. The need for careful metric selection, clear data definitions, and regular audit to manage data quality.

    Co-Designing the Primary Care Individual Social Norms Musculoskeletal Data Dashboard (PRISM) for First Contact Physiotherapy: Consensus-Based Qualitative Study · 2026 · DOI

  • The need for FCPs to practice at an advanced level in the clinical pillar of practice. The lack of a tool like PRISM to provide FCPs with feedback on their clinical activity relative to their peers.

    Co-Designing the Primary Care Individual Social Norms Musculoskeletal Data Dashboard (PRISM) for First Contact Physiotherapy: Consensus-Based Qualitative Study · 2026 · DOI

  • Technical debt and lack of sustainability planning beyond individual project funding cycles. The need for governance and standardization to ensure longitudinal and shared infrastructure.

    An interoperable and reusable research environment for digital medicine · 2026 · DOI

  • Clinical data is longitudinal and shared across studies, but infrastructure is often not designed to be longitudinal and shared. The lack of governance and standardization leads to semantic divergence and technical debt. Prior systems are often project-specific and not designed for reuse or sustainability.

    An interoperable and reusable research environment for digital medicine · 2026 · DOI

  • Traditional OCR systems lack the ability to handle complex data anomalies. The absence of secure and interoperable mechanisms for data exchange has produced operational challenges in dialysis centers. Manual data entry in dialysis centers is time-consuming and error-prone.

    Towards Intelligent Virtual Clerks: AI-Driven Automation for Clinical Data Entry in Dialysis Care · 2025 · DOI

  • Real-record interoperability, usability, and prospective clinical performance remain to be evaluated.

    Design and Technical Evaluation of a Standards-Based System That Delivers Enclave-Derived Case-Finding Models to Patients and Clinicians · 2026 · DOI

  • This system may support more structured nutrition management and workflow efficiency; however, its impact on clinical outcomes such as complications, length of stay, and mortality was not evaluated in this study and should be examined in future research.

    Development and evaluation of an integrated clinical nutrition management system for inpatients · 2026 · DOI

  • Future research is required to measure the impact of the equity dashboard and optimize artificial intelligence dashboard utilization.

    The Impact of Dashboard Utilization on Quality of Care in the Emergency Department: A Systematic Review · 2026 · DOI

  • Thus, little is known about what dietitians need to incorporate technology-based solutions into practice.

    Understanding dietitians’ technology design needs through user-centered design of a clinical decision support system for patient-centered diabetes education materials · 2026 · DOI

  • Patient portals may help close care gaps by enabling patients to initiate services, but their use for diabetes preventive care is understudied.

    Pilot study of a patient portal intervention designed to empower patients to address diabetes care gaps · 2026 · DOI

  • Although client information systems (CIS) should provide social welfare professionals (SWPs) with a comprehensive overview of a client’s situation for case-based knowledge formation (CBKF), research into SWPs’ user experiences is scarce.

    Information system support for case-based knowledge formation in social welfare: a cross-sectional study · 2025 · DOI

  • While identifying potentially eligible individuals in the EHR is largely accepted as effective, little is known about the effectiveness of outreach via EHR compared to outreach via traditional electronic mail (email) communication given equivalent population identification strategies.

    A randomized study comparing patient portal and email communications for trial recruitment · 2025 · DOI

  • Consequently, there currently exists a scarcity of research and gaps in the literature regarding the efficacy, effectiveness, overall performance, and possibly success factors associated with these systems, or conversely, identify the design and implementation deficiencies, as well as the use-based challenges present in them.

    Assessing the usability and performance of digital healthcare systems in Nigerian teaching hospitals: Challenges and future directions · 2025 · DOI

  • Further studies on system, information, and service qualities are needed to improve overall health system digitalization process in Oromia, Ethiopia.

    Evaluating the impact of electronic medical records on healthcare digitalization efforts in Oromia, Ethiopia: A qualitative study · 2025 · DOI

  • Emerging tools such as artificial intelligence (AI)–supported personalised training have the potential to address these challenges, but their applicability and perceived value in resource-constrained contexts remain unclear.

    Perceptions of AI-supported training for electronic health record use in Tanzania: A preliminary exploratory study · 2025 · DOI

  • Little is known about adolescents' perceptions about healthcare's ability to protect online health records.

    Security and Privacy of Online Record Access: A Survey of Adolescents' Views and Experiences in Sweden · 2024 · DOI

  • Lack of data linkage and interoperability between systems undermines best efforts to optimise integrated health information technology solutions.

    System interoperability and data linkage in the era of health information management: A bibliometric analysis · 2024 · DOI

  • Basic demographic data such as date of birth (83% L-MIC, 90% U-MIC) and sex at birth (98% L-MIC, 91% U-MIC) were consistently captured, but equity-related data were poorly documented (ethnicity 48% U-MIC, 59% HIC; disadvantaged group status rarely recorded in 78% of L-MICs).

    Strengthening Oncology Data Systems for Equitable Care in Asia-Pacific: Current Practices and Future Directions · 2026 · DOI

  • Effective oncology data management through oncology information systems (OIS) is essential for high-quality cancer care, yet adoption across the Asia-Pacific (APAC) region varies widely.

    Strengthening Oncology Data Systems for Equitable Care in Asia-Pacific: Current Practices and Future Directions · 2026 · DOI

  • Contribution: Findings contribute to the limited literature on digital health adoption in sub-Saharan Africa and offer practical guidance for laboratories considering LIS procurement and deployment.

    Needs assessment for a laboratory information system at Diagnopath Medical Laboratories in Zimbabwe · 2026 · DOI

  • Whole-genome sequencing (WGS) for every UK newborn is hailed as a leap towards lifelong personalised medicine, yet policymakers have scarcely examined the informatics iceberg beneath the initiative: where, and at what cost, will millions of genomes be stored?

    Sequencing every UK newborn: why cold storage economics should shape policy · 2025 · DOI

  • Real-world implementation is often limited by fragmented systems, repeated transcription, and incomplete auditability - - The study did not involve prospective participant enrollment, additional intervention, biological sample collection, or access to identifiable participant-level clinical…

    A certifiable evidence-chain digital platform supporting decentralized clinical trials: architecture and real-world evaluation · 2026 · DOI

  • The survey highlighted mixed opinions and insufficient knowledge among PCPs regarding the novelties.

    Monitoring the digital healthcare transition in Italy: Initiatives, metrics and feedback from Primary Care Physicians · 2024 · DOI

Most-cited papers in Electronic Health Records Systems

Most recent work

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Open questions raised by papers listed on this page include: (1) Incomplete auditability and lack of data integrity, traceability, and security are major challenges in conventional electronic data capture centric workflows (“A certifiable evidence-chain digital platform supporting decentralized clinical…”, 2026); (2) Lack of standardized documentation for ventral hernia repair operative reports (“Quality review of ventral hernia repair operative reports”, 2026); (3) The lack of a tool like PRISM to provide FCPs with feedback on their clinical activity relative to their peers (“Co-Designing the Primary Care Individual Social Norms Musculoskeletal Data…”, 2026); (4) Technical debt and lack of sustainability planning beyond individual project funding cycles (“An interoperable and reusable research environment for digital medicine”, 2026); (5) Real-record interoperability, usability, and prospective clinical performance remain to be evaluated (“Design and Technical Evaluation of a Standards-Based System That Delivers…”, 2026). 571 gap statements have been mined from Electronic Health Records Systems papers in our 7.9M-paper local library, which holds 3,282 papers on the topic; the gaps come from whichever of those papers state one. They are mostly the research gaps the authors state and the papers' abstracts, plus future-work, limitations and challenges passages. The ones listed below are a selection still marked open; each names the study that raised it, with a DOI link where the paper has one, so you can read the original claim in context.

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