Open research questions in Genetic and phenotypic traits in livestock
133 gap statements mined from Genetic and phenotypic traits in livestock papers in our 4.5M-paper local library, which holds 1,256 papers on the topic — drawn mostly from each paper's own stated research gap, future-work, challenge and limitation notes, and its abstract. The ones listed below are a selection still marked open; each names the study that raised it, with a DOI link where the paper has one.
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What the literature leaves open
There is a lack of research on the genetic improvement of Jeju Black Cattle. There is a need to develop breeding programs that can improve the genetic quality of Jeju Black Cattle.
Genomic Breeding Value Prediction and Accuracy Assessment for Carcass Traits in Jeju Black Cattle Using Hanwoo Reference Populations · 2026 · DOIFuture research should focus on refining genetic models, conducting controlled breeding trials, and leveraging advanced technologies such as AI-based estrous monitoring to create a predictive, precision-based breeding framework that aligns with the socio-economic and ecological realities of the region.
Reproductive Physiology, Genetic Architecture, and Management of Duolang Sheep Under Arid-Zone Production Systems: A Review · 2026 · DOIThe integration of pedigree, phenotype, and genotype data requires efficient computational methods. The need to account for environmental factors that affect fertility traits in dairy cattle.
Genetic Parameters and Weighted Single-Step Genome-Wide Association Studies of Fertility Traits in Chinese Holstein · 2026 · DOIThe need for efficient genetic analysis methods to dissect the molecular mechanisms underlying fertility traits. The lack of studies on the genetic mechanisms of fertility in Chinese Holstein cattle.
Genetic Parameters and Weighted Single-Step Genome-Wide Association Studies of Fertility Traits in Chinese Holstein · 2026 · DOIThere is a need to study the genetic diversity of the Iraqi marsh buffalo. There is a lack of information on the genetic structure of the Iraqi marsh buffalo population.
Complex trait and environment modeling future research should focus more on developing deep learning models for multi-trait, multi-environment, and timeseries prediction. Based on the analysis conducted, several open challenges and promising avenues for future work can be identified.
There is a lack of information on the genetic and environmental factors influencing egg traits in blue-breasted quail. Previous studies have reported heritability estimates for egg traits in other species, but not in blue-breasted quail.
Estimation of Heritability and Permanent Environmental Effects of Egg Traits in the Blue-Breasted Quail (Synoicus chinensis) · 2026 · DOIThere is a need to evaluate the level of inbreeding in Polish Simmental cows and its effect on lactational milk traits. There is a lack of information on the changes in the composition of ancestors in young cows.
Pedigree analysis: estimation of genetic parameters and the effect of inbreeding on dairy traits in Simmental cattle · 2026 · DOIThere is a gap in knowledge about the fertility traits of Saanen goats in Bursa, Turkey. The study fills this gap by providing a comprehensive analysis of the breed's fertility characteristics.
Fertility Traits and Evaluation of Environmental Factors and Body Measurements in Saanen Goats Raised in Bursa · 2026 · DOIFuture studies can build on the study's findings to further refine GWAS-identified QTLs and pinpoint candidate variants and genes. The study's methods can be applied to other traits and species.
Bayesian fine-mapping pinpoints candidate genes and pleiotropic loci of production traits from a chicken backcrossing scheme · 2026 · DOIThe study notes that the medium density of SNP arrays limits the resolution for fine-mapping causal variants. The study aims to overcome this limitation through imputation and Bayesian fine-mapping methods.
Bayesian fine-mapping pinpoints candidate genes and pleiotropic loci of production traits from a chicken backcrossing scheme · 2026 · DOIThe study faces challenges due to the limited number of males in the dataset. The study highlights the challenge of analyzing qualitative morphological characteristics.
Phenotypic characterization of Landim and Pafúri goat populations in Southern Mozambique based on morpho-structural traits and zoometric indices · 2026 · DOIThe study has a limited number of males (n = 6) in the dataset. The study does not perform inferential analysis (Chi-square test) due to low expected frequencies in some qualitative trait categories.
Phenotypic characterization of Landim and Pafúri goat populations in Southern Mozambique based on morpho-structural traits and zoometric indices · 2026 · DOIThe study had to use simplified persistency indicators due to the lack of repeated longitudinal egg production records.
Growth–maturity–egg production trade-offs and candidate gene associations with egg-laying persistency in slow-growing Thai native chickens · 2026 · DOIThe study highlights the need for further research on the genetic basis of egg-laying persistency.
Growth–maturity–egg production trade-offs and candidate gene associations with egg-laying persistency in slow-growing Thai native chickens · 2026 · DOIExternal fertilization is an environmentally sensitive process. Traditional assessment of reproductive capacity in breeders is often impractical. The true breeding values remain unknown.
A non-linear game for two: genetic parameters and prediction of fertilization success using Bayesian and machine learning frameworks · 2026 · DOIThe true breeding values remain unknown. The concordance between tower outputs and EBVs is moderate. The current configuration of the model should be interpreted as predictive scores rather than direct substitutes for breeding values.
A non-linear game for two: genetic parameters and prediction of fertilization success using Bayesian and machine learning frameworks · 2026 · DOIThe study does not report any specific limitations. However, it can be inferred that the large genome size of Korean pine and the limited number of samples may be limitations of the study.
Genetic diversity study and molecular marker development for economic traits in Korean pine based on RAD-Seq · 2026 · DOIFurther studies can be conducted to validate the developed KASP markers in larger populations. The study's findings can be applied to other conifer species with similar genetic characteristics. Further research can be done to explore the genetic diversity of other conifer species.
Genetic diversity study and molecular marker development for economic traits in Korean pine based on RAD-Seq · 2026 · DOIAlthough there are no clear reports in goose ovaries, based on our multi-omics data showing its positive association with clutch length, we speculate FNDC1 might play a beneficial role in ovarian follicular development, which warrants further investigation (Figure 2).
The limitation of pedigree-based methods in detecting distant inbreeding - The potential underestimation of ancient autozygosity using medium-density SNP panels - The need for comprehensive and reliable pedigree…
The need for a comprehensive assessment of inbreeding - The lack of standardization of analytical protocols for inbreeding estimation - The limitation of pedigree-based methods in detecting distant…
The study identifies a gap in the evaluation of the effects of genotype on body parameters and secondary sexual characteristics of Nigerian indigenous cock genotypes.
Genotype effect on growth parameters and secondary sexual characteristics in three Nigerian cock genotypes and their genetic parameters · 2026 · DOIOnly 31 autosomes and a sex chromosome were considered, - The ZJU 1.0 assembly includes only 31 autosomes plus two sex chromosomes, - Limited to duck…
Development and Characterization of a Single Nucleotide Polymorphism Genotyping Panel for Duck Populations · 2026 · DOIFurther genomic studies using the developed SNP panel, - Investigation of the genetic diversity of duck populations, - Application of the SNP panel in breeding…
Development and Characterization of a Single Nucleotide Polymorphism Genotyping Panel for Duck Populations · 2026 · DOI
Most-cited papers in Genetic and phenotypic traits in livestock
- Genome sequence, comparative analysis and haplotype structure of the domestic dog · Nature · 2005 · 1,920 citations
- GAPIT Version 3: Boosting Power and Accuracy for Genomic Association and Prediction · Genomics Proteomics & Bioinformatics · 2021 · 1,190 citations
- OptM : estimating the optimal number of migration edges on population trees using Treemix · Biology Methods and Protocols · 2021 · 404 citations
- A review of deep learning applications for genomic selection · BMC Genomics · 2021 · 357 citations
- Redundancy analysis: A Swiss Army Knife for landscape genomics · Methods in Ecology and Evolution · 2021 · 341 citations
- Review: Genetic selection of high-yielding dairy cattle toward sustainable farming systems in a rapidly changing world · animal · 2021 · 289 citations
- Review: An overview of beef production from pasture and feedlot globally, as demand for beef and the need for sustainable practices increase · animal · 2021 · 258 citations
- Heterosis and Hybrid Crop Breeding: A Multidisciplinary Review · Frontiers in Genetics · 2021 · 223 citations
- Pig genome functional annotation enhances the biological interpretation of complex traits and human disease · Nature Communications · 2021 · 185 citations
- Features and applications of haplotypes in crop breeding · Communications Biology · 2021 · 171 citations
Most recent work
- Predicting enviromically adapted varieties with big data · Genome biology · 2026
- GAPIT version 4: integration of GWAS into genomic prediction · Molecular Biology and Evolution · 2026
- Integrating genomic predictions into an applied Central European wheat breeding program · Theoretical and Applied Genetics · 2026
- BeefAI™ — Prepotency & Heterosis Framework: From Paddock Appeal to Progeny Confidence · Zenodo (CERN European Organization for Nuclear Research) · 2026
- Sharing approaches in predictive genomics across animals, plants and humans · Nature Genetics · 2026
- Strategic global data integration to improve genomic prediction accuracy in tree breeding programs facing resource limitations, a case study in mango · Horticulture Research · 2026
- Deciphering the Regulatory Network of Tail Fat Deposition in Large- and Small-Tailed Han Sheep Through Transcriptome and MicroRNAome Profiling · Biology · 2026
- Sparse testcrossing for early-stage genomic prediction of general combining ability to increase genetic gain in maize hybrid breeding programs · Theoretical and Applied Genetics · 2026
- A century of allopatry: plasticity and rapid selection shape phenotypic trait variability under contrasting environments. · bioRxiv · 2026
- Genetic basis of traits and performance in UK silver birch · bioRxiv · 2026
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