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Open research questions in Genetic Mapping and Diversity in Plants and Animals

169 gap statements mined from Genetic Mapping and Diversity in Plants and Animals papers in our 4.5M-paper local library, which holds 877 papers on the topic — drawn mostly from each paper's own stated research gap, future-work, challenge and limitation notes, and its abstract. The ones listed below are a selection still marked open; each names the study that raised it, with a DOI link where the paper has one.

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What the literature leaves open

  • The lack of a climate-adaptive breeding pipeline to develop climate-resilient rice varieties. The need for advanced genomic tools to improve tolerance to extreme temperatures.

    Harnessing climate-adaptive breeding to accelerate tolerance to extreme temperatures in rice · 2026 · DOI

  • Further studies can investigate the genetic basis of NCLB resistance in other maize populations. The development of tailored breeding strategies for durable resistance can be explored.

    Genetic Insights into NCLB Resistance in Maize (Zea Mays L.) Populations Derived from NEHR Landraces Using Generation Mean Analysis · 2026 · DOI

  • There is a need to understand the underlying gene action governing NCLB resistance. Prior work has focused on qualitative resistance, which is often short-lived.

    Genetic Insights into NCLB Resistance in Maize (Zea Mays L.) Populations Derived from NEHR Landraces Using Generation Mean Analysis · 2026 · DOI

  • Abiotic stress remains a critical factor contributing to up to a 3/4th reduction in global crop yields, posing a significant challenge to food security.

    Harnessing genomics and transcriptomics to explore the genetic and molecular basis of abiotic stress tolerance in minor millets – a comprehensive review · 2026 · DOI

  • The study highlights the need for a predictive framework for breeding-relevant prediction of reproductive timing in lettuce. The paper notes that current methods for selecting lettuce varieties for heat tolerance are limited and often rely on labor-intensive and costly phenotyping.

    GWAS-Guided Compact SNP Panels Enable Breeding-Relevant Prediction of Bolting and Flowering Timing of Lettuce · 2026 · DOI

  • Prior studies have focused on QTL mapping, which can miss small effect loci. The genetic basis of domestication in sorghum is not fully understood.

    Insights into the genetic basis of natural selection and domestication from Sorghum · 2026 · DOI

  • The need to integrate multiple omics sciences. The challenge of scaling up genomic approaches to breeding programs.

    Special Issue “Functional and Structural Genomics Studies for Plant Breeding” · 2026 · DOI

  • The need to sustainably enhance crop productivity and quality in the context of climate change. The limitations of traditional breeding strategies in addressing complex agronomic traits. The potential of genomic approaches to transform breeding strategies.

    Special Issue “Functional and Structural Genomics Studies for Plant Breeding” · 2026 · DOI

  • The lack of understanding of the ERG25 gene family in Trametes versicolor and its response to light stress. The need to investigate the potential functional linkage between ergosterol biosynthesis and transport proteins in T. versicolor. The gap in knowledge about the regulation of ergosterol biosynthesis under varying light conditions.

    Analysis of the ERG25 gene family based on the whole-genome sequence in Trametes versicolor and its response to light stress · 2026 · DOI

  • The limited population size and marker density may affect the accuracy of the results. The need to consider trait genetic architecture to enhance predictive abilities is a challenge.

    Genomic prediction of wild-derived powdery mildew resistance for strawberry (Fragaria × ananassa) pre-breeding · 2026 · DOI

  • Some of the critical gaps in the research include the lack of integration of HTP in speed breeding programs, the cost and training barriers preventing the widespread use of HTP, and the need for collaborative tools and databases for utilizing HTP data across projects.

    High-Throughput Phenotyping: Status and Applications in Rice Breeding · 2026 · DOI

  • Identifying key genes controlling mesocotyl length in sorghum is challenging due to limited research in this area. Understanding the molecular mechanisms underlying mesocotyl elongation is complex. Developing a valuable resource for breeding sorghum varieties with long mesocotyls requires a comprehensive understanding of the genetic regulation of mesocotyl length.

    Genome-Wide Association Uncovered SbERF60 Positively Regulates Mesocotyl Length in Sorghum · 2026 · DOI

  • The study has a limited number of genotypes, which was intentionally chosen to allow high-resolution allelic comparison. The study does not estimate genome-wide diversity parameters at the population level.

    Genetic association and diversity pattern among the prominent West Bengal rice (Oryza sativa L.) landraces based on simple sequence repeat (SSR) mapped from chromosome 1 · 2026 · DOI

  • Further studies can investigate genome-wide diversity parameters at the population level. Future research can explore the application of SSR markers in breeding programs.

    Genetic association and diversity pattern among the prominent West Bengal rice (Oryza sativa L.) landraces based on simple sequence repeat (SSR) mapped from chromosome 1 · 2026 · DOI

  • With the development of these components, AI-driven GP will transition from a theoretical framework to the foundational basis for predictive breeding decisions. These systems will speed up genetic gain, and help farming stay viable in a changing climate.

    Beyond QTL and GWAS: how deep learning, graph models, and multi-omics are reshaping plant genomic prediction analysis · 2026 · DOI

  • Limited haploid seed availability prevented advancement of some genotypes to Screening Stage 2. The study relied on a specific dataset of 295 haploid lines.

    A two-stage screening approach integrated with GWAS for rare phenotypes such as spontaneous haploid genome doubling in maize · 2026 · DOI

  • The study used a limited population size, which may affect the accuracy of the results. The study focused on a specific disease, powdery mildew, and the results may not be generalizable to other diseases. The study used a specific genomic prediction approach, GBLUP, and the results may not be applicable to other approaches.

    Genomic prediction of wild-derived powdery mildew resistance for strawberry (Fragaria × ananassa) pre-breeding · 2026 · DOI

  • The application of speed breeding to other crops to improve their resilience to climate change. The development of new genomic tools to improve tolerance to extreme temperatures.

    Harnessing climate-adaptive breeding to accelerate tolerance to extreme temperatures in rice · 2026 · DOI

  • Further study of the genetic loci associated with mesocotyl length. Use of the identified genetic loci in breeding programs. Investigation of other traits associated with seedling emergence and establishment.

    Identification of Genetic Loci for Mesocotyl Length in Rice (Oryza sativa L.) using Genome-Wide Association Approach · 2026 · DOI

  • Studies on cultivar adaptation to a changing Mediterranean climate - Research on high-value cultivars rising in importance - Further analysis of gene regulatory networks and genetic…

    Integrative Genomics and Phenotyping Strategies to Advance Sustainable Cultivation of European Rice Varieties with Enhanced Nutritional Quality · 2026 · DOI

  • The need to understand how rice interacts with its environment and how different varieties have adapted to diverse climates - The need to develop nutritionally enhanced rice…

    Integrative Genomics and Phenotyping Strategies to Advance Sustainable Cultivation of European Rice Varieties with Enhanced Nutritional Quality · 2026 · DOI

  • Further evaluation of the two-stage SHGD screening approach in different environments. Investigation of the genetic mechanisms underlying SHGD. Development of new DH breeding strategies using the identified genotypes with stable SHGD potential.

    A two-stage screening approach integrated with GWAS for rare phenotypes such as spontaneous haploid genome doubling in maize · 2026 · DOI

  • Further investigation of the identified candidate genes and their roles in domestication. Integration of the findings with other research on crop domestication and improvement.

    Insights into the genetic basis of natural selection and domestication from Sorghum · 2026 · DOI

  • The development of advanced network analysis algorithms to identify core regulatory nodes from integrated datasets. The application of emerging technologies, including artificial intelligence, single-cell omics, and Zameer Hussain Jamali and Muhammad Usama Younas. The integration of heterogeneous datasets from genomics, transcriptomics, and other omics platforms.

    Multi-omics and precision breeding strategies for enhancing biotic and abiotic stress resilience in rice · 2026 · DOI

  • The relationships among the six genes lack experimental validation, - More complex regulatory mechanisms involved in ergosterol synthesis need to be verified through further…

    Analysis of the ERG25 gene family based on the whole-genome sequence in Trametes versicolor and its response to light stress · 2026 · DOI

Most-cited papers in Genetic Mapping and Diversity in Plants and Animals

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Open questions raised by papers listed on this page include: (1) The lack of a climate-adaptive breeding pipeline to develop climate-resilient rice varieties (“Harnessing climate-adaptive breeding to accelerate tolerance to extreme…”, 2026); (2) There is a need to understand the underlying gene action governing NCLB resistance (“Genetic Insights into NCLB Resistance in Maize (Zea Mays L.) Populations…”, 2026); (3) The genetic basis of domestication in sorghum is not fully understood (“Insights into the genetic basis of natural selection and domestication from…”, 2026); (4) The lack of understanding of the ERG25 gene family in Trametes versicolor and its response to light stress (“Analysis of the ERG25 gene family based on the whole-genome sequence in…”, 2026); (5) Future research can explore the application of SSR markers in breeding programs (“Genetic association and diversity pattern among the prominent West Bengal rice…”, 2026). 169 gap statements have been mined from Genetic Mapping and Diversity in Plants and Animals papers in our 4.5M-paper local library, which holds 877 papers on the topic; the gaps come from whichever of those papers state one. They are mostly the research gaps the authors state and the papers' abstracts, plus future-work, limitations and challenges passages. The ones listed below are a selection still marked open; each names the study that raised it, with a DOI link where the paper has one, so you can read the original claim in context.

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