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Open research questions in Maternal and Neonatal Healthcare

157 unresolved questions extracted from the limitations and future-work sections of 1,572 Maternal and Neonatal Healthcare papers in our library. Each links back to the study that raised it.

What the literature leaves open

  • The study faces challenges related to data quality and limitations of the retrospective design. There is a need to establish causality between the Apgar index and maternal and obstetric factors.

    ANÁLISE DO ÍNDICE DE APGAR E SUA RELAÇÃO COM FATORES MATERNOS E OBSTÉTRICOS NO MUNICÍPIO DE CASCAVEL-PR (2013 A 2023) · 2026 · DOI

  • The study uses data from a public database, which may have limitations such as subnotifications and lack of specific information. The study has a retrospective design, which may limit the ability to establish causality.

    ANÁLISE DO ÍNDICE DE APGAR E SUA RELAÇÃO COM FATORES MATERNOS E OBSTÉTRICOS NO MUNICÍPIO DE CASCAVEL-PR (2013 A 2023) · 2026 · DOI

  • The implementation of the E-motive strategy may face structural challenges in public maternity hospitals. The use of tranexamic acid as a first-line drug in postpartum hemorrhage may be limited by its availability and cost. The detection of occult hemodynamic instability can be challenging in low-resource settings.

    A importância do manejo ativo na prevenção da hemorragia pós-parto em maternidades públicas: uma revisão das diretrizes FEBRASGO e OMS (2025) · 2026 · DOI

  • The complexity of the etiology of congenital heart diseases. The need for continuous epidemiological surveillance. The challenge of reducing the impact of congenital heart diseases on neonatal health.

    CASOS DE CARDIOPATIAS CONGÊNITAS EM GOIÁS ENTRE 2021 E 2025: UMA PERSPECTIVA EPIDEMIOLÓGICA PERINATAL E MATERNA. · 2026 · DOI

  • Congenital syphilis is often associated with poor prenatal care and late diagnosis. Nursing interventions can be challenging to implement in resource-poor settings. There is a need for more research on effective nursing interventions for preventing congenital syphilis.

    Atuação da enfermagem na prevenção da sífilis congênita: uma pesquisa integrativa · 2026 · DOI

  • The complexity of the relationship between maternal diseases and congenital heart defects. The need for careful management of maternal diseases during pregnancy.

    DOENÇAS MATERNAS E FATORES DE RISCO PARA CARDIOPATIAS CONGÊNITAS: REVISÃO NARRATIVA · 2026 · DOI

  • The complexity of congenital heart diseases. The need for accurate and reliable data on congenital heart diseases. The importance of monitoring and surveillance of congenital heart diseases.

    PERFIL EPIDEMIOLÓGICO E DISTRIBUIÇÃO POR IDADE MATERNA DAS CARDIOPATIAS CONGÊNITAS EM GOIÁS, BRASIL, 2021–2025 · 2026 · DOI

  • The study identified challenges in the implementation of Integrative and Complementary Practices, including lack of knowledge and infrastructure. The study highlights the need for investment in research, education, and financial incentives to support the development of these practices.

    Práticas Integrativas e Complementares: Descrição das Aplicações Feitas na Atenção Primária à Saúde · 2026 · DOI

  • The high burden of septicemia in Maranhão and Piauí. The lack of completeness regarding the variable race/color. The need for improved healthcare assistance in these states.

    INTERNAÇÕES E MORTALIDADE HOSPITALAR POR SEPTICEMIA NO MARANHÃO E PIAUÍ: SÉRIE HISTÓRICA E DISTRIBUIÇÃO SEGUNDO VARIÁVEIS SOCIODEMOGRÁFICAS, 2016–2025 · 2026 · DOI

  • Pediatric trauma has distinct epidemiological characteristics compared to adult trauma. The current evidence base for managing pediatric trauma is limited. Lockdown measures can have unintended consequences on health outcomes.

    IMPACTO DAS MEDIDAS DE LOCKDOWN DA COVID-19 NO TRAUMA PEDIÁTRICO NO BRASIL · 2026 · DOI

  • Early sugar exposure is a significant public health concern. There is a need for education and prevention strategies to reduce early sugar consumption. Healthcare professionals face challenges in providing guidance on healthy eating habits.

    EXPOSIÇÃO PRECOCE DO AÇÚCAR NA ALIMENTAÇÃO INFANTIL E SEUS IMPACTOS A LONGO PRAZO: UMA REVISÃO INTEGRATIVA · 2026 · DOI

  • The challenge of reducing preterm birth risk. The need to develop effective interventions to address maternal risk factors. The difficulty of establishing causality in quasi-experimental designs.

    Risco materno associado à prematuridade em gestantes acompanhadas por gestão de caso · 2026 · DOI

  • Preterm birth is a significant challenge in neonatal health. The study faced limitations due to the small sample size and lack of standardized protocols.

    APLICAÇÃO DO MÉTODO DE HAMMOCK NA ASSISTÊNCIA A RECÉM-NASCIDOS PREMATUROS COM BAIXO PESO ADMITIDOS EM UNIDADES DE CUIDADOS NEONATAIS · 2026 · DOI

  • The study highlights the challenges of providing qualified nursing care to women with gestational hypertensive syndrome. There is a need for nurses to go beyond technical skills to provide emotional support and build trust with patients.

    ASSISTÊNCIA DE ENFERMAGEM SEM ACOMPANHAMENTO PRÉ-NATAL A MULHERES COM SÍNDROME HIPERTENSIVA GESTACIONAL · 2026 · DOI

  • Interindividual variability in PK/PD, immune response, and genetic background. The risk of adverse effects, including hypersensitivity reactions and pancreatitis. The need for personalized treatment strategies to improve treatment outcomes.

    Optimización del tratamiento con L-asparaginasa en la leucemia linfoblástica aguda pediátrica: revisión del impacto de la farmacocinética, la farmacodinámica y los biomarcadores genéticos · 2026 · DOI

  • The study highlights the importance of addressing the socio-assistance inequities that contribute to mortality from epilepsy. The development of targeted interventions to address these inequities is necessary. The study suggests that public policies are needed to prevent deaths from epilepsy and improve access to specialized care.

    MORTALIDADE POR EPILEPSIA EM ALAGOAS, BRASIL: DESIGUALDADES E PADRÕES EPIDEMIOLÓGICOS (2013–2024) · 2026 · DOI

  • The study faced challenges in terms of the small sample size. The retrospective design of the study may have limited the generalizability of the results.

    Perfil epidemiológico do traumatismo crânioencefálico em lactantes internados na Santa Casa de Campo Grande · 2026 · DOI

  • The lack of awareness and understanding of obstetric violence among health professionals. The need for humanized obstetric care that prioritizes women's autonomy and dignity. The challenge of preventing obstetric violence in healthcare settings.

    VIOLÊNCIA OBSTÉTRICA E SUAS CONSEQUÊNCIA NO PÓS-PARTO SOB À ÓTICA DO ENFERMEIRO OBSTETRA · 2026 · DOI

  • The complexity of symptoms, which favors multimodal approaches. The heterogeneity of the disease, which requires personalized treatments. The need for a combination of strategies, including pharmacological, rehabilitative, psychological, and surgical treatments.

    BENEFÍCIOS DA ABORDAGEM MULTIMODAL NO TRATAMENTO DA ENDOMETRIOSE · 2026 · DOI

  • Assessing joint range of motion in elderly women can be challenging due to age-related changes and health conditions. There is a need for effective and reliable assessment tools for this population.

    Validação Concorrente do Protocolo Normal Flex para Avaliação da Amplitude de Movimento Articular em Mulheres Idosas: Estudo Comparativo com Métodos Goniométricos · 2026 · DOI

  • The disease is chronic and infectious, making it difficult to control. The virus can remain latent in infected animals, making diagnosis challenging.

    LEUCOSE ENZOÓTICA BOVINA EM REBANHO DE CORTE DA REGIÃO METROPOLITANA DO RECIFE, PERNAMBUCO: ASPECTOS CLÍNICOS, SOROLÓGICOS E ANATOMOPATOLÓGICOS · 2026 · DOI

  • The study faces challenges in terms of the limited sample size and the potential biases of the online questionnaire. The research highlights the need for institutional support to promote health literacy and commitment to safe sex.

    DESCOMPASSO ENTRE CONHECIMENTO E PRÁTICA · 2026 · DOI

  • The challenge of visualizing the biliary tract during laparoscopic cholecystectomy. The risk of iatrogenic injuries during the procedure. The need for accurate and safe techniques for fluorescent cholangiography.

    Vía intravesicular VS. Endovenosa para colangiografía fluorescente con verde de indocianina: estudio comparativo · 2026 · DOI

  • There is a need for a validated tool for sepsis screening in pediatric patients. The current tools and protocols may not be effective in early detection and treatment of sepsis.

    Desempenho do Escore Pediátrico de Alerta Simplificado para Rastreio da Sepse na Emergência · 2026 · DOI

  • The influence of private financing on the development of clinical trials. The disparity between the private and public sectors in terms of research protocols and financing. The limited number of protocols and financing in the public sector.

    Caracterización de los protocolos de investigación del sistema de salud público de CABA en el período 2019-2023: ¿qué se investiga, qué se financia y en qué hospitales? · 2026 · DOI

Most-cited papers in Maternal and Neonatal Healthcare

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157 open questions have been extracted from the limitations and future-work passages of 1,572 Maternal and Neonatal Healthcare papers in our library. Each one below links back to the study that raised it, so you can read the original claim in context.

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