Science AI Journal
Neuroscience · Research topic

Open research questions in Neuroethics, Human Enhancement, Biomedical Innovations

224 gap statements mined from Neuroethics, Human Enhancement, Biomedical Innovations papers in our 7.9M-paper local library, which holds 2,705 papers on the topic — drawn mostly from each paper's own stated research gap, future-work, challenge and limitation notes, and its abstract. The ones listed below are a selection still marked open; each names the study that raised it, with a DOI link where the paper has one.

Choosing where to publish on Neuroethics, Human Enhancement, Biomedical Innovations? See the ranked Biology journals.

What the literature leaves open

  • Future research should examine local and subgroup performance, post-deployment monitoring, patient and professional experiences, disability access, distributed accountability, implementation costs, institutional readiness, data governance, and benefit distribution.

    The Incarnate Clinic: Pope Leo XIV’s Magnifica Humanitas, AI Optimization, and the Bioethics of Technological Colonialism in Philippine Healthcare · 2026 · DOI

  • We argue that regulatory or experimental restrictions are warranted only once there is a non-trivial empirical likelihood that a given organoid type can generate valenced experience.

    Neural Organoids: How Should We Handle the Possibility of Sentience? · 2025 · DOI

  • Even if constitutive panpsychism were accepted, the moral relevance of any putative micro experiences would remain undetermined.

    Neural Organoids: How Should We Handle the Possibility of Sentience? · 2025 · DOI

  • Some of the included studies were small-scale, and, therefore, it remains unclear whether the findings could be generalized to the wider population of smart drug enthusiasts.

    Focus on Cognitive Enhancement: A Narrative Overview of Nootropics and “Smart Drug” Use and Misuse · 2025 · DOI

  • Why, then, does it vary in the case of respondents who endorse “foundational distinction”? Further research is needed to clarify this pattern of responses.

    Ethical concerns about embodied brain organoids shaped by foundational distinctions and perceptions of consciousness · 2026 · DOI

  • Generally, NFT collections are limited to a maximum supply of 10,000. Although definitive proof of insider trading is lacking, it is highly likely that this individual acted on insider information, as the requirement to hold 0.

    1. Epigenetics, Preconception Tort Liability, and Public Health, 2. Regulating Cryptocurrency Airdrops, 3. Medical AI, Civil Recourse Theory, and No-Fault Compensation · 2026 · DOI

  • The paper also emphasizes the challenge of ensuring that such experiments are not repeated in the future.

    Stranger things. Neurocientíficos militares y de la CIA en proyectos secretos de experimentación humana en los Estados Unidos (1945-1975) · 2026 · DOI

  • It highlights the need for further research into the involvement of the military and CIA in these projects.

    Stranger things. Neurocientíficos militares y de la CIA en proyectos secretos de experimentación humana en los Estados Unidos (1945-1975) · 2026 · DOI

  • Participants emphasized the need for contextual interpretation of neural data and transparent communication with clients when neurotechnology, including neural data is used. The findings support cautious optimism for the role of neurotechnology in forensic care, contingent on further research and interdisciplinary dialogue.

    Neuroscience informed risk assessment and management in forensic mental healthcare: a qualitative analysis of ethical and legal challenges and practice-oriented recommendations · 2026 · DOI

  • One could, for example, imagine the construction of qualitative maps of continuity, where the traces left by an individual in terms of their technologies, ecological footprints, and mnemonics could be explored. Methodological note: conceptual synthesis under acceleration Futurity philosophy is often not accompanied by a particular empirical methodology because the future is by definition not yet known.

    ENHANCEMENT TO CONTINUITY · 2026 · DOI

  • The paper identifies a gap in the current discourse surrounding artificial intelligence, which focuses primarily on capability rather than the effects of AI on human beings. The paper argues that the preservation of human developmental processes is a crucial challenge in the AI era.

    Delegated Cognition. Generative AI and the Future of Human Development. · 2026 · DOI

  • It remains to be clarified in what sense these two approaches complement and integrate with one another. In what sense do these two approaches together shed light on the desirability of biotechnological interventions in aging?

    Clashing Perspectives? Two Approaches to the Desirability of Biological Aging · 2026 · DOI

  • Further research is needed to explore the ontological underpinning of AI. The relationship between GenAI and the Western cosmocracy of control should be further examined. Alternative regulatory approaches that account for the uncertainty and ambiguity of GenAI should be developed.

    Challenging the Cosmocracy of Certainty and Engaging the AI Hyperpharmakon: Regulation, Ethics, and Resonance · 2026 · DOI

  • The assumption that AI paradoxical effects can be tamed through prescriptive regulatory practices is challenged. The ontological underpinning of AI is not well understood. The relationship between GenAI and the Western cosmocracy of control is not well explored.

    Challenging the Cosmocracy of Certainty and Engaging the AI Hyperpharmakon: Regulation, Ethics, and Resonance · 2026 · DOI

  • LeGall (2020) pointed out that, despite decades of effort by various individuals, the locations of the skulls of Songea Mbano and Mangi Meli remain unknown. The specific purpose of these plaster casts remains unclear. On 19 August, Hambruch noted in his diary: ‘The measurements are not understood, the natives remain shy.

    Changing Ethics of Human Remains · 2026 · DOI

  • It highlights the need to critically evaluate the intersection of these advances with neoliberalism and human life.

    La bioética del transhumanismo o la bioideología neoliberal · 2026 · DOI

  • It highlights the need for a historical and interdisciplinary perspective on these advances.

    La bioética del transhumanismo o la bioideología neoliberal · 2026 · DOI

  • There is a need for interdisciplinary discussion on the implications of transhumanism. The study highlights a gap in understanding the opinions and attitudes of experts on transhumanist technologies.

    Transhumanist Scenarios of the (Post)Human Future · 2026 · DOI

  • The God of the Bible ap‑ pears more in control of existence than the Egyptian Ra (limited to the Nile basin), Anu, the Father of the Sumerian gods, or the Babylonian Marduk, who extended his reach through conquests carried out by beloved devotees.

    Technology and Theology, as Artificial Intelligence Comes of Age · 2026 · DOI

  • The systematic construction of a posthuman ethics requires in-depth development, particularly in developing an ethical framework to guide our coexistence with non-human actants—from animals and ecosystems to advanced AI.

    Deconstructing "Cogito": Descartes' Specter and the Emergence of Posthuman Subjects · 2026 · DOI

  • Detection of invasions of mental privacy might arise from intricate neurotechnological systems that function imperceptibly to the user. Attribution of culpable individual may be challenging if cognitive interference transpires. Regulatory design is a further problem.

    Evaluating the Philosophical Necessity of a "Constitutional Right to Mental Privacy" · 2026 · DOI

  • The package includes a physical AI extension: in large-scale physical AI systems, the body may no longer be limited to a humanoid shell, robotic limb, or local sensor-actuator frame.

    SΔϕ-52 — Body as Non-Deferrable Cost Return: Operational Body, Body Theater, and Distributed AI Body Infrastructure (v1.0, AI-Readable Package) · 2026 · DOI

  • The implementation of neuro-rights into functional legal frameworks. The development of advanced regulatory regulation to safeguard cognitive autonomy. The exploration of the intersection of brain-computer interfaces with established civil freedoms.

    Evaluating the Philosophical Necessity of a "Constitutional Right to Mental Privacy" · 2026 · DOI

  • The paper proposes a structured research agenda to operationalize and test the hypothesis of delegated cognition dependency (DCD) across multiple levels of analysis.

    Delegated Cognition. Generative AI and the Future of Human Development. · 2026 · DOI

  • The book identifies a gap in the current understanding of organismal agency in biology and philosophy. The book aims to contribute to the discussion on the role of agency in biology and philosophy.

    Jana Švorcová (vyd.), Organismal Agency. Biological Concepts and Their Philosophical Foundations · 2026 · DOI

Most-cited papers in Neuroethics, Human Enhancement, Biomedical Innovations

Most recent work

Find a gap in your own Neuroethics, Human Enhancement, Biomedical Innovations sub-topic

This page shows what the Neuroethics, Human Enhancement, Biomedical Innovations literature already flags as unresolved. To narrow it to your specific question, search the Research Gap Finder: the search is free with a free account and lists the papers closest to your topic first. Unlocking that topic (50 credits, charged once) fills the comparison table from our 7.9M-paper local library and writes the gaps from its rows.

Open the Research Gap Finder →

Related topics in Neuroscience

Autism Spectrum Disorder Research
2,492 open questions
Alzheimer's disease research and treatments
1,987 open questions
Functional Brain Connectivity Studies
1,482 open questions
Neuroinflammation and Neurodegeneration Mechanisms
1,431 open questions
Neural and Behavioral Psychology Studies
1,095 open questions
Transcranial Magnetic Stimulation Studies
1,024 open questions
EEG and Brain-Computer Interfaces
980 open questions
Neurobiology of Language and Bilingualism
885 open questions
Open questions raised by papers listed on this page include: (1) Further research is needed to clarify this pattern of responses (“Ethical concerns about embodied brain organoids shaped by foundational…”, 2026); (2) Although definitive proof of insider trading is lacking, it is highly likely that this individual acted on insider information, as the requirement to hold 0 (“1. Epigenetics, Preconception Tort Liability, and Public Health, 2. Regulating…”, 2026); (3) Methodological note: conceptual synthesis under acceleration Futurity philosophy is often not accompanied by a particular empirical methodology because the future is by definition not yet known (“ENHANCEMENT TO CONTINUITY”, 2026); (4) It remains to be clarified in what sense these two approaches complement and integrate with one another (“Clashing Perspectives? Two Approaches to the Desirability of Biological Aging”, 2026); (5) Further research is needed to explore the ontological underpinning of AI (“Challenging the Cosmocracy of Certainty and Engaging the AI Hyperpharmakon:…”, 2026). 224 gap statements have been mined from Neuroethics, Human Enhancement, Biomedical Innovations papers in our 7.9M-paper local library, which holds 2,705 papers on the topic; the gaps come from whichever of those papers state one. They are mostly the research gaps the authors state and the papers' abstracts, plus future-work, limitations and challenges passages. The ones listed below are a selection still marked open; each names the study that raised it, with a DOI link where the paper has one, so you can read the original claim in context.

Tools for your next paper

Gaps & Literature SearchFind open questions in any field — 1,100,000+ open gaps mined from our own library.Pre-CheckIs your paper ready? Acceptance odds for top, mid and open/emerging journals, in seconds.Journal FinderA ranked shortlist of target journals from a 17,500-venue index.Duplicate Publication CheckerCheck for prior publication across 7 sources and our local library.Citation GeneratorFreeA DOI or title → APA, MLA, Vancouver, Chicago, BibTeX, RIS. No signup.Graphical Abstract MakerFreeTurn your findings into a colorblind-safe graphical abstract.

How Pre-Check worksHow AI Review works

Compare the category — Honest roundups of the AI research tools, ours listed alongside the alternatives.

Command palette

Jump anywhere, run any action.