Open research questions in Neuroscience and Music Perception
359 unresolved questions extracted from the limitations and future-work sections of 1,489 Neuroscience and Music Perception papers in our library. Each links back to the study that raised it.
What the literature leaves open
The complexity and location of cortico-basal ganglia pathways complicates direct measurement, - EMG signatures are not wholly consistent with pause-then-cancel predictions, - A tractable cognitive model of the pause-then-cancel framework has yet to be proposed
Separating Pause from Cancel? Evaluating the Pause-then-Cancel Model in Complex Stopping Tasks · 2026 · DOILeveraging cognitive models to reconcile purported neural mechanisms with action stopping, - Integrating EMG and EEG with cognitive models, - Mapping neural signatures onto model-derived parameters
Separating Pause from Cancel? Evaluating the Pause-then-Cancel Model in Complex Stopping Tasks · 2026 · DOIInvestigating the causal dynamics of creative cognition, - Using TMS-EEG to study other complex behaviors
No socio-demographic information (e.g., age, sex, education level, cultural background) was collected, - The study had a limited sample size, - The findings should be interpreted as pertaining to the specific sample tested rather than to the general population
Investigate the relationship between music, emotions, and color in different cultures and age groups, - Examine the effect of musical training on the association between tonality, tempo, and emotional responses, - Explore the application of the findings in music therapy and color design
The study only included participants who did not speak Mandarin or Tagalog. The study had a limited sample size of 104 participants. The study relied on self-report measures for demographic information and musical background.
Trusting self-evaluation: predicting music and language performance from subjective ratings · 2026 · DOIInvestigating the relationship between music and language in different populations. Examining the effects of musical training on language processing. Developing more comprehensive measures of musical and linguistic ability.
Trusting self-evaluation: predicting music and language performance from subjective ratings · 2026 · DOIThe study only included 42 university students, which may not be representative of the general population - The study only used a within-subjects design, which may have limitations in terms of external validity - The study did not control for individual differences in music preferences or emotional responses to music - The study only used a limited range of music stimuli, which may not be generalizable to other types of music - The study relied on self-reported measures of emotional state and willingness to help, which may be subject to biases
Investigate the effects of music on prosocial behavior in different cultural contexts - Examine the neural mechanisms underlying the effects of music on prosocial decision-making - Develop and test interventions that use music to promote prosocial behavior in real-world settings - Explore the potential therapeutic applications of music in promoting social bonding and cooperation
There is a lack of comprehensive contemporary literature reviews on improvisation in North Indian classical music. The paper identifies a paucity of research on learning, practice, memorisation, and performance beyond the Western Classical tradition. There is a need for further research on the cognitive processes involved in improvisation and composition in non-Western musical traditions.
Pedagogical strategies for the development of improvisation and composition in North Indian classical music · 2025 · DOIFurther research is needed to clarify the associations between EAP and cognition, - Studies could investigate the use of Gaussian graphical models and Bayesian networks in other populations, - Research could explore the potential of EAP and cognition as early-stage targets or surrogate endpoints in schizophrenia
Clarifying directional dependence among measures of early auditory processing and cognition in schizophrenia: leveraging Gaussian graphical models and Bayesian networks · 2024 · DOIThe gap identified by the paper is the limitation of latent variable models in accounting for relationships among individual measures of cognition and EAP. There is a need for a data-driven approach to identify directional relationships among neurophysiologic and cognitive variables.
Clarifying directional dependence among measures of early auditory processing and cognition in schizophrenia: leveraging Gaussian graphical models and Bayesian networks · 2024 · DOIThe causal mechanisms underlying musical improvisation remain poorly understood. The functional role of premotor regions in orchestrating improvised versus externally cued motor performance is not well understood. There is a need for a more direct and causal understanding of the neural mechanisms underlying musical improvisation.
further interdisciplinary research on learning and memory in non-notated musical systems
Pedagogical strategies for the development of improvisation and composition in North Indian classical music · 2025 · DOIA review of the developmental aspect of episodic memory is needed to elucidate how the events organize themselves to support memory function
However, the attentional mechanisms underlying age-related speech comprehension difficulties in multitalker situations remain unclear.
Both music and language are found in all known human societies, yet no studies have compared similarities and differences between song, speech, and instrumental music on a global scale.
Globally, songs and instrumental melodies are slower and higher and use more stable pitches than speech: A Registered Report · 2024 · DOIHow the brain represents these dimensions and whether their encoding is specialized for music remains unknown.
Yet, it remains unknown i) whether emotional connotations and structural features of music elicit discrete bodily sensations and ii) whether these sensations are culturally consistent.
A corollary discharge signal supports this function in animals; however, in humans, its exact origin and temporal dynamics remain unknown.
Nonetheless, how temporal processing evolves across the lifetime as well as the links with the underlying neural substrates remains unclear.
However, the neural mechanisms of this improvement remain unclear due to insufficient neuroimaging evidence.
Five-week music therapy improves overall symptoms in schizophrenia by modulating theta and gamma oscillations · 2024 · DOIFuture studies can use this dataset to investigate the neural mechanisms of auditory attention in individuals with autism spectrum disorder (ASD). The dataset can also be used to study the effects of auditory training on cognitive flexibility in older adults.
A human EEG dataset to study cognitive flexibility during auditory discrimination under real-world distractors · 2026 · DOIThere is a scarcity of EEG datasets that capture the transient neural mechanisms of attention reorientation in the presence of real-world auditory distractors. The ability to discriminate between competing sounds is compromised in conditions like tinnitus and autism spectrum disorder (ASD).
A human EEG dataset to study cognitive flexibility during auditory discrimination under real-world distractors · 2026 · DOIExploring the applications of cBCIs in various fields, including music, art, and neuroscience. Developing new algorithms and methods for extracting and tracking bioharmonic structure and transitional harmony.
The harmonicity of brain dynamics: A neurophenomenological approach to creative biofeedback · 2026 · DOI
Most-cited papers in Neuroscience and Music Perception
- The N1 Wave of the Human Electric and Magnetic Response to Sound: A Review and an Analysis of the Component Structure · Psychophysiology · 1987 · 2,713 citations
- Guidelines for using human event‐related potentials to study cognition: Recording standards and publication criteria · Psychophysiology · 2000 · 1,786 citations
- The role of attention in auditory information processing as revealed by event-related potentials and other brain measures of cognitive function · Behavioral and Brain Sciences · 1990 · 1,330 citations
- Communication of emotions in vocal expression and music performance: Different channels, same code? · Psychological Bulletin · 2003 · 1,220 citations
- Emotional responses to music: The need to consider underlying mechanisms · Behavioral and Brain Sciences · 2008 · 1,175 citations
- On Quantifying Surprise: The Variation of Event‐Related Potentials With Subjective Probability · Psychophysiology · 1977 · 978 citations
- A Scale for the Measurement of the Psychological Magnitude Pitch · The Journal of the Acoustical Society of America · 1937 · 722 citations
- Brain Generators Implicated in the Processing of Auditory Stimulus Deviance: A Topographic Event‐Related Potential Study · Psychophysiology · 1990 · 647 citations
- Varieties of Musical Disorders · Annals of the New York Academy of Sciences · 2003 · 576 citations
- The relationship between spike rate and synchrony in responses of auditory-nerve fibers to single tones · The Journal of the Acoustical Society of America · 1980 · 569 citations
Most recent work
- Approaching environmentalism for high ESG ratings: Evidence from dynamic multi-signal interpretation · Long Range Planning · 2026
- Serial dependence in time perception requires consistent motor responses, not shared memory alone · British Journal of Psychology · 2026
- Concert formats influence how audiences experience live classical music · Humanities and Social Sciences Communications · 2026
- Cerebral glucose utilisation during musical emotions: A multimodal functional PET/MRI study:A multimodal functional PET/MRI study · Åbo Akademi University Research Portal · 2026
- Optimized feature gains explain and predict successes and failures of human selective listening · Nature Human Behaviour · 2026
- Somatosensory rhythms and cerebellar-basal ganglia beta-band dynamics in Parkinson's disease · bioRxiv · 2026
- Duration reproduction under memory pressure: Modeling the roles of visual memory set size in duration encoding and reproduction · Cognition · 2026
- Deep Beats, Deep Thoughts? Predicting General Cognitive Ability from Natural Music-Listening Behavior · Journal of Intelligence · 2026
- Western Adults' Neural Responses to an Ambiguous Rhythm: Effects of Priming With and Without Active Attention · Psychophysiology · 2026
- Polyrhythms in the Brain: Metrical Priming, Acoustic Balance, and Perceptual Biases · Annals of the New York Academy of Sciences · 2026
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