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Open research questions in Pressure Ulcer Prevention and Management

71 gap statements mined from Pressure Ulcer Prevention and Management papers in our 4.5M-paper local library, which holds 459 papers on the topic — drawn mostly from each paper's own stated research gap, future-work, challenge and limitation notes, and its abstract. The ones listed below are a selection still marked open; each names the study that raised it, with a DOI link where the paper has one.

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What the literature leaves open

  • Although this observation is reassuring, it should be interpreted with caution, given the limited sample size (n = 135) and short follow-up duration, which are insufficient to detect rare or delayed adverse events.

    A comparison of the effects of Temporin atomizable mucosal liquid dressing vs. routine skin care on wound healing in critically ill patients: a retrospective analysis · 2026 · DOI

  • Therefore, this should be considered one of the limitations of the present study. Finally, 90% of the cases in this study were early-stage (d1–d2), and the utility of PhA for advanced-stage pressure ulcers (D3 or higher) has not been validated.

    Association between pressure ulcers and phase angle in older adults residing in long-term care facilities · 2026 · DOI

  • In light of the limitations of this study, future research should focus on the following areas. Additionally, another limitation of this study is that the evaluation criteria primarily rely on expert image interpretation rather than bedside clinical examination. The absence of this functionality is another limitation of this study.

    Development and preliminary clinical validation of a mobile health application for pressure injury staging in ICU patients · 2026 · DOI

  • There is a lack of studies investigating the effect of progressive mobilization on the incidence of pressure ulcers in patients with impaired consciousness. There is a need for further research on the use of mobilization as a nursing intervention in the intensive care unit.

    Penerapan Mobilisasi Progresif terhadap Kejadian Dekubitus pada Pasien dengan Penurunan Kesadaran di HCU Anggrek 2 Rumah Sakit Dr. Moewardi · 2026 · DOI

  • Future studies can investigate the use of automated control mechanisms for dynamic cushion configuration. Future research can explore the development of intelligent wheelchair seating systems. Future studies can evaluate the effectiveness of the designed cushion in real-world scenarios.

    Optimizing wheelchair cushion design through pressure mapping analysis for pressure ulcer risk reduction · 2026 · DOI

  • The real-world implementation of AI-enabled tools in rural environments remains under-evaluated, particularly regarding contextual factors that influence adoption, sustainability, and equitable impact.

    Monitoring and evaluation of an artificial intelligence-enhanced wound care intervention in a rural health network: defining stakeholder expectations and shared priorities · 2026 · DOI

  • While these results do not provide definitive evidence that ATM improves healing outcomes in pressure ulcers relative to SOC, they do suggest a potential signal warranting further investigation.

    Global burden to local action: A pilot feasibility study of placental-based solutions for complex pressure ulcers using real-world evidence · 2026 · DOI

  • As a result, the study could not evaluate healing trajectories, time to 50% reduction, or non-linear wound healing patterns, an important limitation given the complex trajectory of chronic pressure ulcers.

    Global burden to local action: A pilot feasibility study of placental-based solutions for complex pressure ulcers using real-world evidence · 2026 · DOI

  • There is a lack of studies on the effectiveness of preventive care in improving skin hydration in patients with limited mobility after stroke. Prior work has not addressed the use of daily monitoring of corneometry and sebumetry in high-risk patients.

    Changes in the Biophysical Parameters of the Skin Barrier in Pressure-Prone Areas in Patients with Limited Mobility During Early Post-Stroke Rehabilitation: Clinical Case Reports · 2026 · DOI

  • This scoping review highlights the growing use of objective technological approaches in skin assessment for early pressure injury detection, while simultaneously exposing a critical gap in clinical practice: the lack of evidence examining routine visual and tactile assessment methods. Routine visual assessment remains insufficient, highlighting a critical equity gap.

    Skin Assessment Strategies for Identification of Pressure Injuries in Dark-Skin-Tone Patients: A Scoping Review · 2026 · DOI

  • Future research should explore the development and support of expanded person-centred multidisciplinary team models across broader age groups and community settings to enhance clinical implementation of PI prevention and management strategies.

    Does teamwork make the dream work? A scoping review of multidisciplinary teams in pressure injury prevention and management · 2026 · DOI

  • Serial assessment with the Pressure Ulcer Scale for Healing (PUSH) supports monitoring of pressure ulcers, but the interpretation of early improvement and short-term fluctuations remains uncertain.

    Early PUSH Response, Maintenance, and Short-term Wound DDynamics: A Secondary Landmark Analysis of the RISE_UP Randomized Trial · 2026 · DOI

  • The relationship between subepidermal moisture (SEM) assessment and pain as early indicators of pressure ulcer development remains unclear.

    The Relationship Between Subepidermal Moisture Assessment and Pain Measurements in Predicting Pressure Ulcer Development in At‐Risk Adults · 2026 · DOI

  • Despite the increasing incidence of MDRPIs in critically ill patients, there has been insufficient research focusing specifically on trauma ICU populations in South Korea.

    Characteristics of and Risk Factors for Medical Device-Related Pressure Injuries in Trauma Patients in Intensive Care Units: A Retrospective Case–Control Study · 2025 · DOI

  • Skin tears (ST), a type of traumatic wound commonly seen in the older adult population, are notable for the lack of data on older adults who continue their own care at home.

    Skin tears in older adults people receiving home care · 2025 · DOI

  • Future research should explore the long-term impacts of well-trained nursing assistants on patient outcomes and expand the PIPM competencies scope required by nursing assistants.

    Exploring nursing assistants’ competencies in pressure injury prevention and management in nursing homes: a qualitative study using the iceberg model · 2025 · DOI

  • Future research could consider the related findings of SARs as they emerge, similar documents from the rest of the UK, and international perspectives Practical implications This analysis highlights the multitude of complex social and health situations that gives rise to pressure ulcers among people living at home.

    Home pressures: failures of care and pressure ulcer problems in the community – the findings of serious case reviews · 2017 · DOI

  • Limited facility availability of antidecubitus mattresses. Clinical conditions of patients, such as mechanical ventilation or decreased consciousness, limited mobility and made repositioning difficult.

    A Descriptive Study of Nurses’ Implementation of Pressure Ulcer Prevention Bundle Care in Total Care Patients · 2026 · DOI

  • The study did not account for anthropometric variation across Indonesian subpopulations. The study used a limited range of body weights and heights.

    Optimizing wheelchair cushion design through pressure mapping analysis for pressure ulcer risk reduction · 2026 · DOI

  • Limited resources and availability of services in rural and remote settings. Geographical barriers in rural and remote settings. Workforce shortages in rural and remote settings.

    Monitoring and evaluation of an artificial intelligence-enhanced wound care intervention in a rural health network: defining stakeholder expectations and shared priorities · 2026 · DOI

  • Limited mobility increases the risk of skin barrier impairment. Pressure-related skin damage can lead to serious health complications. Current preventive care regimens may not be effective in improving skin hydration.

    Changes in the Biophysical Parameters of the Skin Barrier in Pressure-Prone Areas in Patients with Limited Mobility During Early Post-Stroke Rehabilitation: Clinical Case Reports · 2026 · DOI

  • Hemodynamic instability, sedation, and limited staffing are unique barriers to patient movement in ICU settings. The study had to adjust for the baseline SOFA score to evaluate the effectiveness of the advanced care protocol. The study had to account for the potential impact of the SOFA score on ulcer occurrence and mortality.

    Pressure Ulcers and Nursing-Led Mobilization Protocols in ICU Patients: A Retrospective Observational Cohort Study · 2025 · DOI

  • Futuras pesquisas devem investigar a eficácia de diferentes estratégias de prevenção da lesão por pressão. É necessário desenvolver protocolos de padronização de técnicas para descompressão local, controle da pressão, umidade e temperatura da pele.

    ATUAÇÃO DO ENFERMEIRO NA PREVENÇÃO DA LESÃO POR PRESSÃO: REVISÃO INTEGRATIVA · 2026 · DOI

  • A lesão por pressão é um grave problema de saúde pública, especialmente em pacientes idosos hospitalizados ou em tratamento domiciliar. A prevenção da lesão por pressão é fundamental para evitar complicações e melhorar a qualidade de vida dos pacientes.

    ATUAÇÃO DO ENFERMEIRO NA PREVENÇÃO DA LESÃO POR PRESSÃO: REVISÃO INTEGRATIVA · 2026 · DOI

  • This study represents the first attempt to describe the barriers and facilitators to evidence-based IAPI prevention practices among operating room nurses using the CFIR 2.0 framework.

    A qualitative study of facilitators and barriers to intraoperative acquired pressure injury prevention implementation in operating room nurses based on the CFIR framework · 2026 · DOI

Most-cited papers in Pressure Ulcer Prevention and Management

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Open questions raised by papers listed on this page include: (1) There is a lack of studies investigating the effect of progressive mobilization on the incidence of pressure ulcers in patients with impaired consciousness (“Penerapan Mobilisasi Progresif terhadap Kejadian Dekubitus pada Pasien dengan…”, 2026); (2) Future studies can investigate the use of automated control mechanisms for dynamic cushion configuration (“Optimizing wheelchair cushion design through pressure mapping analysis for…”, 2026); (3) There is a lack of studies on the effectiveness of preventive care in improving skin hydration in patients with limited mobility after stroke (“Changes in the Biophysical Parameters of the Skin Barrier in Pressure-Prone…”, 2026); (4) The relationship between subepidermal moisture (SEM) assessment and pain as early indicators of pressure ulcer development remains unclear (“The Relationship Between Subepidermal Moisture Assessment and Pain Measurements…”, 2026); (5) Skin tears (ST), a type of traumatic wound commonly seen in the older adult population, are notable for the lack of data on older adults who continue their own care at home (“Skin tears in older adults people receiving home care”, 2025). 71 gap statements have been mined from Pressure Ulcer Prevention and Management papers in our 4.5M-paper local library, which holds 459 papers on the topic; the gaps come from whichever of those papers state one. They are mostly the research gaps the authors state and the papers' abstracts, plus future-work, limitations and challenges passages. The ones listed below are a selection still marked open; each names the study that raised it, with a DOI link where the paper has one, so you can read the original claim in context.

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