Science AI Journal
Medicine · Research topic

Open research questions in Airway Management and Intubation Techniques

216 gap statements mined from Airway Management and Intubation Techniques papers in our 7.9M-paper local library, which holds 1,886 papers on the topic — drawn mostly from each paper's own stated research gap, future-work, challenge and limitation notes, and its abstract. The ones listed below are a selection still marked open; each names the study that raised it, with a DOI link where the paper has one.

Choosing where to publish on Airway Management and Intubation Techniques? See the ranked Medicine journals.

What the literature leaves open

  • Owing to the short duration of the follow-up in the present study, the potential for late tissue regrowth after IRE could not be assessed and warrants further investigation.

    Irreversible Electroporation for the Treatment of Pediatric Adenotonsillar Hypertrophy · 2026 · DOI

  • Further multi-center studies are warranted to validate its efficacy and safety in diverse clinical settings and among high-risk (ASA physical status III or IV) pediatric populations.

    A novel nasal cannula versus conventional face mask for preventing hypoxemia during flexible bronchoscopy in children: a randomized controlled trial · 2026 · DOI

  • Second, because spontaneous recovery was not monitored until a TOF ratio ≥ 90% was achieved, differences in recovery between the hand and foot beyond the minimal block remain unknown.

    Comparison of electromyographic recovery from rocuronium-induced neuromuscular block between the adductor pollicis and the flexor hallucis brevis muscles in pediatric patients younger than two years · 2026 · DOI

  • The MASCAN classification shows what this looks like for a single domain; the equivalent work for difficult laryngoscopy and difficult intubation remains to be done. Second, prospective multicentre registries capturing patient, operator, device and environmental variables in parallel, since the latter are systematically absent from current datasets.

    Beyond Mallampati: From Universal Bedside Tests to Precision Airway Risk Stratification · 2026 · DOI

  • Moving forward, there is a clear need for targeted research aimed at refining current strategies and exploring new interventions that may improve both success rates and patient safety. One promising area is the development and implementation of robust, standardized protocols for managing difficult neonatal airways, which could help mitigate the variability in first-pass success rates and reduce TIAEs.

    Neonatal Tracheal Intubation in the NICU: A Literature Review · 2025 · DOI

  • Finally, this review is narrative in nature and we did not conduct a systematic review of the literature on airway management in resource-limited settings; and a few recommendations may lack evidence or generalizability.

    Airway Management in the ICU and Emergency Department in Resource-Limited Settings · 2026 · DOI

  • Although our institutional experience suggests that the technique is relatively easy to learn, these observations are anecdotal and have not been systematically studied.

    A novel endoscopy-guided airway management strategy for lateral decubitus endoscopic procedures · 2026 · DOI

  • However, the specific values of airway positive pressure that can be generated by different oxygen flow rates remain to be further studied.

    A novel nasal cannula versus conventional face mask for preventing hypoxemia during flexible bronchoscopy in children: a randomized controlled trial · 2026 · DOI

  • Recommendations on nasal intubation depths in term or preterm newborns are scarce, although this is the preferred route in some countries.

    Prospective evaluation of recommendations for nasal insertion depths in neonatal intubation: a prospective quality assurance study · 2025 · DOI

  • Consequently, the persistence or progression of atelectasis beyond the early postoperative phase could not be evaluated, and longitudinal postoperative imaging was not assessed. Third, lung ultrasound assessments were limited to the immediate postoperative period, with measurements performed preoperatively and 10 min after airway device removal.

    Laryngeal mask airway versus endotracheal tube for preventing postoperative atelectasis after laparoscopic surgery: a randomized controlled trial · 2026 · DOI

  • Patients with obesity (BMI>30), head and neck pathology, and higher ASA grades were excluded; therefore, applicability of results to these populations remains uncertain.

    Use of ultrasonography as a novel tool of airway assessment in patients undergoing general anesthesia and surgery and its comparison with Cormack-Lehane classification: a prospective observational study · 2026 · DOI

  • Overinflation of the cuff can compress the pharyngolaryngeal mucosa, causing local tissue ischemia, edema, and even nerve injury. The lack of routine monitoring and standardized safe thresholds for ILMA cuff pressure.

    Individualized regulation of inflatable laryngeal mask airway cuff pressure reduces postoperative pharyngolaryngeal pain in elderly patients: a randomized controlled trial · 2026 · DOI

  • The lack of routine monitoring and standardized safe thresholds for ILMA cuff pressure. The need for an individualized ILMA cuff pressure regulation strategy based on physiological characteristics and sealing principles.

    Individualized regulation of inflatable laryngeal mask airway cuff pressure reduces postoperative pharyngolaryngeal pain in elderly patients: a randomized controlled trial · 2026 · DOI

  • One challenge is the limited availability of human cadavers for research purposes. Another challenge is the need for a controlled laboratory setting to evaluate ventilatory performance.

    Comparison of ventilation with second-generation supraglottic airway devices in a prospective randomized cadaver study · 2026 · DOI

  • The limited exposure of residents and young physicians to real pediatric intubations is a significant gap. The paper identifies the need for high-fidelity simulations to replicate complex clinical scenarios, including emergency situations.

    High Fidelity Simulations to Improve Pediatric Airway Management: A Narrative Review · 2026 · DOI

  • Systematic research on the effects of HFNC therapy on clinical outcomes is necessary. The evaluation of educational programs focusing on the integration of technical and communication skills is essential. Assessments of nurses' emotional intelligence in relation to patient safety should be conducted.

    Nursing Approach to Patients Receiving HFNC Therapy During ERCP · 2026 · DOI

  • There is a need to compare the clinical performance of different SGAs in infant populations. The ideal pediatric SGA should ensure a rapid seal, minimal trauma, and reliable ventilation.

    Comparative efficacy of size 1 I-gel and Air-Q supraglottic airway devices in infants: A randomized controlled trial · 2026 · DOI

  • Future prospective trials are warranted to explore the potential complex relationships between supine CP, position-induced CP changes, and anesthesia duration and to assess the clinical need for continuously regulating LMA cuff pressure after head rotation during prolonged otologic surgeries to optimize postoperative recovery.

    Intraoperative supraglottic airway device, anesthetic, and mechanical factors associated with acute postoperative sore throat in elective tympanoplasty: a retrospective cohort study · 2026 · DOI

  • Lateral head rotation during surgery alters LMA intracuff pressure (CP), but the relationship between these pressure changes and POST remains unclear.

    Intraoperative supraglottic airway device, anesthetic, and mechanical factors associated with acute postoperative sore throat in elective tympanoplasty: a retrospective cohort study · 2026 · DOI

  • Assessment of the posterior laryngeal structuresparticularly the aryepiglottic folds and interarytenoid areais limited by air shadowing on ultrasound.

    Ultrasound evaluation of the upper airway in children: technique and applications · 2026 · DOI

  • AI is expected to play an increasingly important role in airway management as computational capabilities, data availability, and algorithm performance continue to improve. Although current applications are primarily focused on difficult airway prediction and procedural support, future developments may transform multiple aspects of airway assessment, decision-making, training, and clinical practice.

    Artificial Intelligence in Airway Management: Current Evidence and Future Perspectives · 2026 · DOI

  • Since the study population is from a university teaching hospitals that caters to different population subsets from across the country, it may not be applicable for ethnicities from other countries which can explain that Lin et al had a DMV with TT > 6.

    Ultrasound Guided Airway Parameters for Predicting Difficult Mask Ventilation: A Prospective Observational Study · 2026 · DOI

  • The complexity of the BMV process - The need for careful consideration of varying factors such as airway patency…

    Bag-Mask Ventilation Is Basic—Or Is It? · 2026 · DOI

  • Gaps in pediatric airway management practice and safety - Underuse of RSI and reliance…

    Evolution in pediatric emergency airway management over a decade at a tertiary center in Pakistan · 2026 · DOI

  • Breaths/min 0–5 cm H2O 6–8 mL/kg ideal body weight <30 cm H2O Tolerate pH $ 7.20 Data from Manthous, Weingart, Mosier et al., and Leatherman.

    Letter to the Editor: Insight into emergency endotracheal intubation in critically ill and strategies beyond equipment · 2026 · DOI

Most-cited papers in Airway Management and Intubation Techniques

Most recent work

Find a gap in your own Airway Management and Intubation Techniques sub-topic

This page shows what the Airway Management and Intubation Techniques literature already flags as unresolved. To narrow it to your specific question, search the Research Gap Finder: the search is free with a free account and lists the papers closest to your topic first. Unlocking that topic (50 credits, charged once) fills the comparison table from our 7.9M-paper local library and writes the gaps from its rows.

Open the Research Gap Finder →

Related topics in Medicine

Artificial Intelligence in Healthcare and Education
4,869 open questions
Dementia and Cognitive Impairment Research
3,297 open questions
Cancer Immunotherapy and Biomarkers
2,687 open questions
Liver Disease Diagnosis and Treatment
2,481 open questions
Substance Abuse Treatment and Outcomes
2,366 open questions
Sports Performance and Training
2,276 open questions
Mosquito-borne diseases and control
2,124 open questions
Parkinson's Disease Mechanisms and Treatments
2,117 open questions
Open questions raised by papers listed on this page include: (1) Further multi-center studies are warranted to validate its efficacy and safety in diverse clinical settings and among high-risk (ASA physical status III or IV) pediatric populations (“A novel nasal cannula versus conventional face mask for preventing hypoxemia…”, 2026); (2) Because spontaneous recovery was not monitored until a TOF ratio ≥ 90% was achieved, differences in recovery between the hand and foot beyond the minimal block remain unknown (“Comparison of electromyographic recovery from rocuronium-induced neuromuscular…”, 2026); (3) The MASCAN classification shows what this looks like for a single domain; the equivalent work for difficult laryngoscopy and difficult intubation remains to be done (“Beyond Mallampati: From Universal Bedside Tests to Precision Airway Risk…”, 2026); (4) The lack of routine monitoring and standardized safe thresholds for ILMA cuff pressure (“Individualized regulation of inflatable laryngeal mask airway cuff pressure…”, 2026); (5) There is a need to compare the clinical performance of different SGAs in infant populations (“Comparative efficacy of size 1 I-gel and Air-Q supraglottic airway devices in…”, 2026). 216 gap statements have been mined from Airway Management and Intubation Techniques papers in our 7.9M-paper local library, which holds 1,886 papers on the topic; the gaps come from whichever of those papers state one. They are mostly the research gaps the authors state and the papers' abstracts, plus future-work, limitations and challenges passages. The ones listed below are a selection still marked open; each names the study that raised it, with a DOI link where the paper has one, so you can read the original claim in context.

Tools for your next paper

Gaps & Literature SearchFind open questions in any field — 1,100,000+ open gaps mined from our own library.Pre-CheckIs your paper ready? Acceptance odds for top, mid and open/emerging journals, in seconds.Journal FinderA ranked shortlist of target journals from a 17,500-venue index.Duplicate Publication CheckerCheck for prior publication across 7 sources and our local library.Citation GeneratorFreeA DOI or title → APA, MLA, Vancouver, Chicago, BibTeX, RIS. No signup.Graphical Abstract MakerFreeTurn your findings into a colorblind-safe graphical abstract.

How Pre-Check worksHow AI Review works

Compare the category — Honest roundups of the AI research tools, ours listed alongside the alternatives.

Command palette

Jump anywhere, run any action.