Open research questions in Child Nutrition and Feeding Issues
157 unresolved questions extracted from the limitations and future-work sections of 977 Child Nutrition and Feeding Issues papers in our library. Each links back to the study that raised it.
What the literature leaves open
The study is a secondary analysis of data collected from two independent cohorts. The study only examined cross-sectional associations between household chaos and appetitive traits. Longitudinal and experimental studies are needed to clarify temporality and underlying mechanisms. The study primarily included higher-SES families.
Associations between household chaos and appetitive traits in preschoolers and preadolescents · 2026 · DOIThe mechanisms by which household chaos relates to childhood obesity risk are unclear. Prior research has not fully examined the associations between household chaos and appetitive traits in preschoolers and preadolescents.
Associations between household chaos and appetitive traits in preschoolers and preadolescents · 2026 · DOIThe role of the parenting environment is also theorized as mutually beneficial for both early language and mental health, but the relationship between these three constructs has rarely been studied together.
From child to context: Joint consideration of toddler language and irritability regulation with maternal responsiveness · 2026 · DOIFuture research should focus on clarifying its core elements, goals and outcome measures.
A Systematic Scoping Review to Identify Core Elements of Responsive Feeding Therapy for Children With Paediatric Feeding Disorder · 2026 · DOIFuture research should focus on standardizing diagnostic criteria and developing culturally sensitive interventions.
While these methods are often studied for their nutritional implications, their impact on maternal mental health, particularly generalized anxiety disorder (GAD), remains understudied.
Maternal anxiety during solid food introduction: insights from a comparative feeding practices study · 2025 · DOICurrent data suggest a link between gastrointestinal problems in ASD and the microbiota, but the amount of evidence is limited.
Unraveling the Connections: Eating Issues, Microbiome, and Gastrointestinal Symptoms in Autism Spectrum Disorder · 2025 · DOIBackground/Objectives: Research on the safety and efficacy of high-dose folinic acid in Chinese children with autism spectrum disorder (ASD) is limited, and the impact of folate metabolism gene polymorphisms on its efficacy remains unclear.
Safety and Efficacy of High-Dose Folinic Acid in Children with Autism: The Impact of Folate Metabolism Gene Polymorphisms · 2025 · DOIDespite growing evidence, the link between B12 and ASD remains inconclusive due to inconsistent findings across studies.
The need for dietician and health professional input and support is key, whereas a lack of guidelines acts as a barrier to blended feeding.
BACKGROUND: The main cause of growth and development delays remains unknown, but it can occur as an interaction between genetic, environmental, and socio-economic factors.
Prevalence and socio-economic determinants of growth and developmental delays among Iranian children aged under five years: A cross sectional study · 2024 · DOITheir intake of fruits and vegetables is inadequate and hence their intake of vitamins and minerals is insufficient, contributing to stunting.
The odds of having obesity in Egyptian children with autism spectrum disorders is higher than stunting compared to healthy developing peers: a national survey · 2024 · DOIWhile antibiotics are the primary treatment for SIBO, their effectiveness in promoting weight gain among malnourished children remains uncertain.
Small Intestinal Bacterial Overgrowth and Childhood Malnutrition: A Comprehensive Review of Available Evidence · 2024 · DOIThe etiology and mechanisms of autism and autism spectrum disorder (ASD) are not yet fully understood.
Modulation of Gut Microbiome and Autism Symptoms of ASD Children Supplemented with Biological Response Modifier: A Randomized, Double-Blinded, Placebo-Controlled Pilot Study · 2024 · DOIPrevious studies have found a tendency towards food selectivity with food monotony and difficulties with food texture in children with ASD, but studies in this area, especially in Brazil, are still scarce.
Eating Behavior and Nutritional Profile of Children with Autism Spectrum Disorder in a Reference Center in the Amazon · 2024 · DOIThe review also highlights the need for standardized treatment protocols and further research on the long-term outcomes of these disorders, aiming to enhance therapeutic strategies and family support systems.
Development and Management of Avoidant/Restrictive Food Intake Disorder and Food Neophobia in Pediatric Patients with Food Allergy: A Comprehensive Review · 2024 · DOITherapeutic diets, including ketogenic, high-antioxidant, gluten-free and casein-free, and probiotic-rich diets, show potential in managing ASD symptoms like behavior, communication, GI issues, and oxidative stress, though the evidence is limited.
Investigation of the long-term efficacy and safety of atypical antipsychotics in children with autism spectrum disorder. Further study of emerging therapies, such as microbiota transfer therapy and high-dose folinic acid.
Medical treatment of autism spectrum disorder in children: Current evidence, controversies, and clinical challenges · 2026 · DOILimited understanding of the efficacy and safety of medical treatments for autism spectrum disorder in children. Need for more research on emerging therapies and biomarker-driven interventions.
Medical treatment of autism spectrum disorder in children: Current evidence, controversies, and clinical challenges · 2026 · DOIFuture research should focus on developing effective early identification and intervention strategies for eating disorders in childhood. Future research should investigate the role of family and school contexts in the development and prevention of eating disorders.
Identificação precoce e intervenção dos transtornos alimentares na infância: uma revisão sistematizada do papel da escola e da família · 2026 · DOIThere is a need for early identification and intervention strategies for eating disorders in childhood. The existing literature lacks a comprehensive review of the risk factors and early manifestations of eating disorders in childhood.
Identificação precoce e intervenção dos transtornos alimentares na infância: uma revisão sistematizada do papel da escola e da família · 2026 · DOIIndividuals with eating disorders may experience heightened sensitivity to sensory experiences, leading to anxiety and avoidance. The sensory properties of cutlery can be complex and multifaceted, making it challenging to identify the most important characteristics. There is a need for further research on the relationship between cutlery preferences and eating disorder symptoms.
The role of nonfood objects, such as cutlery, in shaping eating experiences has been largely overlooked. Prior research has focused primarily on food texture, taste, and olfactory cues, as well as environmental factors. There is a need for further research on the sensory properties of cutlery in eating disorder care.
Limited treatment options for ASD. Inconsistent evidence for CAT approaches. Small sample sizes and methodological limitations in prior studies.
Complementary and Alternative Treatments for Autism Spectrum Disorder: A Comprehensive Review · 2026 · DOIThe role of father involvement in complementary feeding practices remains insufficiently synthesized. There is a need to examine the relationship between father involvement and children’s nutritional status.
Father Involvement in Complementary Feeding Practices and Nutritional Status among Children Aged 6–24 Months: A Systematic Review Based on Friedman Family Theory · 2026 · DOI
Most-cited papers in Child Nutrition and Feeding Issues
- Gastrointestinal Symptoms in Autism Spectrum Disorder: A Meta-analysis · PEDIATRICS · 2014 · 716 citations
- Evaluation, Diagnosis, and Treatment of Gastrointestinal Disorders in Individuals With ASDs: A Consensus Report · PEDIATRICS · 2010 · 681 citations
- Comprehensive Feeding Practices Questionnaire: Validation of a New Measure of Parental Feeding Practices · Journal of Pediatric Psychology · 2007 · 609 citations
- Food Selectivity and Sensory Sensitivity in Children with Autism Spectrum Disorders · Journal of the American Dietetic Association · 2010 · 605 citations
- Prospective Appraisal of Complaints of Adverse Reactions to Foods in Children During the First 3 Years of Life · PEDIATRICS · 1987 · 589 citations
- Feeding Problems and Nutrient Intake in Children with Autism Spectrum Disorders: A Meta-analysis and Comprehensive Review of the Literature · Journal of Autism and Developmental Disorders · 2013 · 548 citations
- Food Selectivity in Children with Autism Spectrum Disorders and Typically Developing Children · The Journal of Pediatrics · 2010 · 536 citations
- Studies on 5-hydroxyindole metabolism in autistic and other mentally retarded children · The Journal of Pediatrics · 1961 · 462 citations
- Gastrointestinal Problems in Children with Autism, Developmental Delays or Typical Development · Journal of Autism and Developmental Disorders · 2013 · 454 citations
- A Comparison of Eating Behaviors Between Children with and Without Autism · Journal of Autism and Developmental Disorders · 2004 · 438 citations
Most recent work
- Efficacy and Safety of Micronutrient Treatment for Irritability in Adolescents: 8-Week Double-Blinded Randomized Placebo-Controlled Trial (BEAM) · Journal of the American Academy of Child & Adolescent Psychiatry · 2026
- When Medically Required Food Avoidance Goes Awry: A Conceptual Framework of ARFID as an Underrecognized Clinical Complication of Food Allergy · International Journal of Eating Disorders · 2026
- Clinical Practice Guideline for Diagnosis and Management of Faltering Weight · PEDIATRICS · 2026
- The Impact of Socioeconomic Status and Different Treatment Modalities on Children With Faltering Weight: Technical Report · PEDIATRICS · 2026
- The Benefits and Harms of Endoscopy and Other Diagnostic Tests to Detect Underlying Conditions in Children With Faltering Weight: Technical Report · PEDIATRICS · 2026
- Family meals and behavioral development: The role of feeding strategies and mealtime emotional climate. · Journal of Family Psychology · 2026
- Self-feeding and communicative development from 12 to 24 months of age: An observational study · Child Development · 2026
- Associations between infant growth and cognitive development: Insights from EEG functional connectivity and power spectral density · Child Development · 2026
- Clinicians' Experiences With Providing Compulsory Nasogastric Tube Feeding: A Commentary on Offringa et al. (2025) · International Journal of Eating Disorders · 2026
- Intensive Multidisciplinary Intervention for Young Children With ARFID : Clinical Outcomes and Parental Experiences From a Prospective Cohort Study · International Journal of Eating Disorders · 2026
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