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Open research questions in Health and Medical Research Impacts

238 gap statements mined from Health and Medical Research Impacts papers in our 7.9M-paper local library, which holds 2,568 papers on the topic — drawn mostly from each paper's own stated research gap, future-work, challenge and limitation notes, and its abstract. The ones listed below are a selection still marked open; each names the study that raised it, with a DOI link where the paper has one.

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What the literature leaves open

  • Limited time and resources for research engagement. Limited knowledge of research processes and low confidence with research methodologies. Organisational cultures that prioritise service delivery over scholarly activity.

    Barriers to Research and Quality Improvement in Nephrology: Nurses and Allied Health Professionals' Perspectives · 2026 · DOI

  • Limited understanding of the barriers to research engagement among nephrology nurses and allied health professionals. Limited knowledge of the factors that influence research engagement, including capability, opportunity, and motivational factors. Limited research on the perspectives of nephrology nurses and allied health professionals on barriers to research and quality improvement.

    Barriers to Research and Quality Improvement in Nephrology: Nurses and Allied Health Professionals' Perspectives · 2026 · DOI

  • Among Hispanic undergraduate students, the association between research-related coursework and research interest remains largely underexplored.

    Research interest in nursing undergraduate students: an exploration of research-linked courses · 2026 · DOI

  • Future research should explore the implementation and effectiveness of these strategies across varied settings to advance faculty development and the field's scholarly impact.

    Building a program of research in medical education: recommendations from the professional literature · 2025 · DOI

  • Little is known regarding the geographic disparity in the distribution of phase 1-3 clinical trials of new cancer treatments in the US and the associated factors.

    Geographic disparity in the distribution of cancer clinical trials in the United States and the associated factors · 2024 · DOI

  • To explore and summarise published literature with regards to secondments to clinical research and to identify the gaps in research to inform further work.

    Research delivery secondments: A scoping review · 2024 · DOI

  • Although there is a suggestion that secondments could positively impact staff retention, there is limited evidence about the benefit for the organisation or for patient care.

    Research delivery secondments: A scoping review · 2024 · DOI

  • There is a need for context-specific evaluation strategies for BERD programs. There is a lack of understanding of the effectiveness of BERD programs in supporting CTS.

    Advancing Translational Science through Biostatistics, Epidemiology, and Research Design Consultations: A Multi-Perspective Evaluation of the Georgia CTSA BERD Program · 2026 · DOI

  • The limitations of this study mainly include: first, although the quasi-experimental design with natural grouping can reflect real training situations, selection bias cannot be completely excluded; second, single-center research limits the external validity of the results; third, the follow-up time is only 1 year, and the long-term impact on postgraduate graduation achievements cannot be assessed.

    A Quasi-Experimental Study of a Dual-Supervisor Training Model and Self-Reported Research Training Needs among Clinical Professional Degree Postgraduates · 2026 · DOI

  • Future research should examine how dynamics of value alignment and structural opportunity may evolve over time and influence the trajectory of research engagement and RCI across medical training.

    Experiences shaping research career intention among Black, Hispanic, and Indigenous-identifying first-year allopathic medical students in the United States: A qualitative study · 2026 · DOI

  • Research competence is a core attribute of contemporary medical imaging and radiation therapy (MIRT), however, how research skills are taught and assessed across international radiography programs remains poorly understood.

    Exploring how research skills are taught and assessed in medical imaging and radiation therapy higher education: An international snapshot · 2026 · DOI

  • One challenge is the limited availability of comprehensive training for peer review. Another challenge is the need to engage early career researchers in peer reviews.

    Effectiveness of the researcher-led “Peerspectives” peer review training course on review quality, knowledge, and skills among doctoral students in the biomedical sciences: a pre-post study · 2026 · DOI

  • Future research could evaluate the long-term impact of the Peerspectives course on the knowledge and skills of participants. Future research could also explore the effectiveness of the course in different contexts and populations.

    Effectiveness of the researcher-led “Peerspectives” peer review training course on review quality, knowledge, and skills among doctoral students in the biomedical sciences: a pre-post study · 2026 · DOI

  • Methodological choices in defining first-time PI status, including the distinction between start-time and index-time exposures and the confounding role of project lifecycle stage, have not been systematically addressed in workforce analyses of the 2025 disruption.

    Effect of the 2025 National Institutes of Health grants disruption on first-time and mechanism-first principal investigators: a cohort study of 80,976 active awards · 2026 · DOI

  • Limited practical involvement in research among undergraduate dental students. Lack of research methodology courses in the curriculum. Difficulty in applying sequential research procedures among students.

    Knowledge, attitude, and practices toward scientific research among undergraduate dental students in Davangere city - A questionnaire survey · 2026 · DOI

  • There is a knowledge-practice gap among undergraduate dental students, with strong theoretical awareness but limited practical involvement. Prior studies have reported a lack of research involvement among students despite positive perceptions.

    Knowledge, attitude, and practices toward scientific research among undergraduate dental students in Davangere city - A questionnaire survey · 2026 · DOI

  • The interaction between H2S, sGC activity, and oxidative stress in pulmonary arteries is not fully understood. However, their interaction with immune cells remains insufficiently characterised, and understanding size- and dose-dependent immune effects is essential to reduce inflammatory risks and guide safe biomedical translation.

    Basic Medical Sciences: International Scientific Conference on Medicine and Health Sciences of the University of Latvia, 2026 · 2026 · DOI

  • The IACH will explore new frontiers of hematology, including AI and cell therapy access. The academy will investigate sustainability in healthcare. The IACH will develop new programs for physicians, nurses, pharmacists, and patients.

    The International Academy for Clinical Hematology (IACH) 2026–2030 strategic vision and roadmap: Building the global reference for education, collaboration, and innovation in clinical hematology · 2026 · DOI

  • Where comparison data were available, specialized electives/streams and short-term curricula were associated with increased presentations and/or publications, while other intervention types showed mixed results.

    Promoting Scholarly Activity in Pediatric Postgraduate Training: A Scoping Review · 2025 · DOI

  • Family medicine is generally perceived as a less research-oriented environment. Research during training is considered to compromise the more important task of clinical activities learning.

    Cultivating a Culture of Research in Saudi Board Family Medicine Program · 2026 · DOI

  • Inadequate structural guidance and mentorship limit undergraduate research participation. Developing research aptitude during undergraduate training is essential, but often neglected.

    Integrating research into medical education: the conceptualization and establishment of a student-led undergraduate (UG) research committee in India · 2026 · DOI

  • The absence of baseline (pre-intervention) quantitative data on research knowledge limited statistical comparisons. Outcomes relied on self-reported activity logs and institutional records, which may underreport informal projects. Nonetheless, triangulation from multiple sources and consistent upward trends lend credibility to the findings.

    Integrating research into medical education: the conceptualization and establishment of a student-led undergraduate (UG) research committee in India · 2026 · DOI

  • While prior work has examined URiM-specific barriers to academic medicine careers more broadly, few studies have focused on the early medical school period or investigated how RCI specifically begins to emerge and evolve.

    Experiences shaping research career intention among Black, Hispanic, and Indigenous-identifying first-year allopathic medical students in the United States: A qualitative study · 2026 · DOI

  • Technological adoption barriers in resource-limited regions.

    The International Academy for Clinical Hematology (IACH) 2026–2030 strategic vision and roadmap: Building the global reference for education, collaboration, and innovation in clinical hematology · 2026 · DOI

  • Following the identification of gaps in research education resources and curricula in translational geroscience (2), the NIA funded a proposal to create the Geroscience Education and Training (GET) Network…

    Bringing Geroscience into the Mainstream: From Education to Clinical Practice, What Will It Take? · 2024 · DOI

Most-cited papers in Health and Medical Research Impacts

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Open questions raised by papers listed on this page include: (1) There is a need for context-specific evaluation strategies for BERD programs (“Advancing Translational Science through Biostatistics, Epidemiology, and…”, 2026); (2) Future research should examine how dynamics of value alignment and structural opportunity may evolve over time and influence the trajectory of research engagement and RCI across medical training (“Experiences shaping research career intention among Black, Hispanic, and…”, 2026); (3) Research competence is a core attribute of contemporary medical imaging and radiation therapy (MIRT), however, how research skills are taught and assessed across international radiography programs remains poorly understood (“Exploring how research skills are taught and assessed in medical imaging and…”, 2026); (4) Future research could evaluate the long-term impact of the Peerspectives course on the knowledge and skills of participants (“Effectiveness of the researcher-led “Peerspectives” peer review training course…”, 2026); (5) Prior studies have reported a lack of research involvement among students despite positive perceptions (“Knowledge, attitude, and practices toward scientific research among…”, 2026). 238 gap statements have been mined from Health and Medical Research Impacts papers in our 7.9M-paper local library, which holds 2,568 papers on the topic; the gaps come from whichever of those papers state one. They are mostly the research gaps the authors state and the papers' abstracts, plus future-work, limitations and challenges passages. The ones listed below are a selection still marked open; each names the study that raised it, with a DOI link where the paper has one, so you can read the original claim in context.

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